This paper introduces a new Plug-and-Play (PnP) alternating direction of multipliers (ADMM) scheme based on a recently proposed denoiser using the Schroedinger equation's solutions of quantum physics. The efficiency of the proposed algorithm is evaluated for Poisson image deconvolution, which is very common for imaging applications, such as, for example, limited photon acquisition. Numerical results show the superiority of the proposed scheme compared to recent state-of-the-art techniques, for both low and high signal-to-noise-ratio scenarios. This performance gain is mostly explained by the flexibility of the embedded quantum denoiser for different types of noise affecting the observations.
We present a new convolutional neural network (CNN) based ImageJ plugin for fluorescence microscopy image denoising with an average improvement of 7.5 dB in peak signal-to-noise ratio (PSNR) and denoising instantly within 80 msec.
A Zero-Shot Deep Image Prior Framework for Denoising and Deconvolution in Fluorescence Microscopy
Wenzhou Key Laboratory of Biomedical Imaging（温州生物医学成像重点实验室）；Zhejiang Key Laboratory of Soft Matter Biomedical Materials（浙江软物质生物医学材料重点实验室）；Wenzhou Institute, University of Chinese Academy of Sciences（中国科学院大学温州研究院）；Postgraduate Training Base Alliance of Wenzhou Medical University（温州医学院研究生联合培养基地联盟）
UCA（蔚蓝海岸大学）；CNRS（法国国家科学研究中心）；INRIA（法国国家信息与自动化研究所）；University of Bath（巴斯大学）
The spatial resolution of images of living samples obtained by fluorescence microscopes is physically limited due to the diffraction of visible light, which makes the study of entities of size less than the diffraction barrier (around 200 nm in the x-y plane) very challenging. To overcome this limitation, several deconvolution and super-resolution techniques have been proposed. Within the framework of inverse problems, modern approaches in fluorescence microscopy reconstruct a super-resolved image from a temporal stack of frames by carefully designing suitable hand-crafted sparsity-promoting r…
Tensor decomposition has proven to be a strong tool in various 3D image processing tasks such as denoising and super-resolution. In this context, we recently proposed a canonical polyadic decomposition (CPD) based algorithm for single image super-resolution (SISR). The algorithm has shown to be an order of magnitude faster than popular optimization-based techniques. In this work, we investigated the added value brought by Tucker decomposition. While CPD allows a joint implementation of the denoising and deconvolution steps of the SISR model, with Tucker decomposition the denoising is realized …
Plug and play (P&P) algorithms iteratively apply highly optimized image denoisers to impose priors and solve computational image reconstruction problems, to great effect. However, in general the "effective noise", that is the difference between the true signal and the intermediate solution, within the iterations of P&P algorithms is neither Gaussian nor white. This fact makes existing denoising algorithms suboptimal. In this work, we propose a CNN architecture for removing colored Gaussian noise and combine it with the recently proposed VDAMP algorithm, whose effective noise follows a predicta…
Due to the development of deep learning-based denoisers, the plug-and-play strategy has achieved great success in image restoration problems. However, existing plug-and-play image restoration methods are designed for non-blind Gaussian denoising such as zhang et al (2022), the performance of which visibly deteriorate for unknown noises. To push the limits of plug-and-play image restoration, we propose a novel framework with blind Gaussian prior, which can deal with more complicated image restoration problems in the real world. More specifically, we build up a new image restoration model by reg…
Collaborative Innovation Center for Biomedical Engineering, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology（华中科技大学武汉光电国家研究中心生物医学工程协同创新中心）；Britton Chance Center and MOE Key Laboratory for Biomedical Photonics, School of Engineering Sciences, Huazhong University of Science and Technology（华中科技大学工程科学学院Britton Chance中心及教育部生物医学光子学重点实验室）；School of Mathematics and Economics, Hubei University of Education（湖北第二师范学院数学与经济学院）
Convolution system is linear and time invariant, and can describe the optical imaging process. Based on convolution system, many deconvolution techniques have been developed for optical image analysis, such as boosting the space resolution of optical images, image denoising, image enhancement and so on. Here, we gave properties on N-dimensional convolution. By using these properties, we proposed image deconvolution method. This method uses a series of convolution operations to deconvolute image. We demonstrated that the method has the similar deconvolution results to the state-of-art method. T…
A Deep Unrolling Model with Hybrid Optimization Structure for Hyperspectral Image Deconvolution
Department of Computer Engineering and Informatics, Patras University（计算机工程与信息学院，帕特拉大学）；Department Digital Media and Communication, Ionian University（数字媒体与通信系，伊奥尼亚大学）
This paper presents a novel deformable registration framework, leveraging an image prior specified through a denoising function, for severely noise-corrupted placental images. Recent work on plug-and-play (PnP) priors has shown the state-of-the-art performance of reconstruction algorithms under such priors in a range of imaging applications. Integration of powerful image denoisers into advanced registration methods provides our model with a flexibility to accommodate datasets that have low signal-to-noise ratios (SNRs). We demonstrate the performance of our method under a wide variety of denoi…
This paper presents a novel method for restoring digital videos via a Deep Plug-and-Play (PnP) approach. Under a Bayesian formalism, the method consists in using a deep convolutional denoising network in place of the proximal operator of the prior in an alternating optimization scheme. We distinguish ourselves from prior PnP work by directly applying that method to restore a digital video from a degraded video observation. This way, a network trained once for denoising can be repurposed for other video restoration tasks. Our experiments in video deblurring, super-resolution, and interpolation …
We propose a general framework for solving inverse problems in the presence of noise that requires no signal prior, no noise estimate, and no clean training data. We only require that the forward model be available and that the noise be statistically independent across measurement dimensions. We build upon the theory of $\mathcal{J}$-invariant functions (Batson & Royer 2019, arXiv:1901.11365) and show how self-supervised denoising \emph{à la} Noise2Self is a special case of learning a noise-tolerant pseudo-inverse of the identity. We demonstrate our approach by showing how a convolutional neur…
Plug-and-Play optimization recently emerged as a powerful technique for solving inverse problems by plugging a denoiser into a classical optimization algorithm. The denoiser accounts for the regularization and therefore implicitly determines the prior knowledge on the data, hence replacing typical handcrafted priors. In this paper, we extend the concept of plug-and-play optimization to use denoisers that can be parameterized for non-constant noise variance. In that aim, we introduce a preconditioning of the ADMM algorithm, which mathematically justifies the use of such an adjustable denoiser. …
Centre Suisse d’Electronique et de Microtechnique (CSEM)（瑞士电子与微技术中心（CSEM））；School of Computer and Communication Sciences, École Polytechnique Fédérale de Lausanne (EPFL)（洛桑联邦理工学院（EPFL）计算机与通信科学学院）
Plug-and-play denoisers can be used to perform generic image restoration tasks independent of the degradation type. These methods build on the fact that the Maximum a Posteriori (MAP) optimization can be solved using smaller sub-problems, including a MAP denoising optimization. We present the first end-to-end approach to MAP estimation for image denoising using deep neural networks. We show that our method is guaranteed to minimize the MAP denoising objective, which is then used in an optimization algorithm for generic image restoration. We provide theoretical analysis of our approach and show…
Score-Based Turbo Message Passing for Plug-and-Play Compressive Image Recovery
Department of Information Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR（信息工程系，香港中文大学（深圳校区））；National Key Lab. of Wireless Commun., Uni. of Electronic Sci. and Tech. of China, Chengdu, China（无线通信国家重点实验室，电子科技大学，成都，中国）
The Plug-and-Play (PnP) ADMM algorithm is a powerful image restoration framework that allows advanced image denoising priors to be integrated into physical forward models to generate high quality image restoration results. However, despite the enormous number of applications and several theoretical studies trying to prove the convergence by leveraging tools in convex analysis, very little is known about why the algorithm is doing so well. The goal of this paper is to fill the gap by discussing the performance of PnP ADMM. By restricting the denoisers to the class of graph filters under a linea…
The Plug-and-Play (PnP) framework makes it possible to integrate advanced image denoising priors into optimization algorithms, to efficiently solve a variety of image restoration tasks generally formulated as Maximum A Posteriori (MAP) estimation problems. The Plug-and-Play alternating direction method of multipliers (ADMM) and the Regularization by Denoising (RED) algorithms are two examples of such methods that made a breakthrough in image restoration. However, while the former method only applies to proximal algorithms, it has recently been shown that there exists no regularization that exp…
A new Plug-and-Play (PnP) alternating direction of multipliers (ADMM) scheme is proposed in this paper, by embedding a recently introduced adaptive denoiser using the Schroedinger equation's solutions of quantum physics. The potential of the proposed model is studied for Poisson image deconvolution, which is a common problem occurring in number of imaging applications, such as limited photon acquisition or X-ray computed tomography. Numerical results show the efficiency and good adaptability of the proposed scheme compared to recent state-of-the-art techniques, for both high and low signal-to-…
Recent work has shown the effectiveness of the plug-and-play priors (PnP) framework for regularized image reconstruction. However, the performance of PnP depends on the quality of the denoisers used as priors. In this letter, we design a novel PnP denoising prior, called multiple self-similarity net (MSSN), based on the recurrent neural network (RNN) with self-similarity matching using multi-head attention mechanism. Unlike traditional neural net denoisers, MSSN exploits different types of relationships among non-local and repeating features to remove the noise in the input image. We numerical…
In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and specificity. A medical image could be corrupted by both intrinsic noise, due to the device limitations, and, by extrinsic signal perturbations during image acquisition. Nowadays, CAD deep learning applications pre-process images with image denoising models to reinforce learning and prediction. In this work, an innovative and lightweight deep multiscale convol…
Purdue University（普渡大学）；Lawrence Berkeley National Laboratory（劳伦斯伯克利国家实验室）；Los Alamos National Laboratory（洛斯阿拉莫斯国家实验室）；Air Force Research Laboratory（美国空军研究实验室）
Many material and biological samples in scientific imaging are characterized by non-local repeating structures. These are studied using scanning electron microscopy and electron tomography. Sparse sampling of individual pixels in a 2D image acquisition geometry, or sparse sampling of projection images with large tilt increments in a tomography experiment, can enable high speed data acquisition and minimize sample damage caused by the electron beam. In this paper, we present an algorithm for electron tomographic reconstruction and sparse image interpolation that exploits the non-local redundanc…
Washington University in St. Louis（圣路易斯华盛顿大学）；University of California, Riverside（加州大学河滨分校）；Los Alamos National Laboratory（洛斯阿拉莫斯国家实验室）
The plug-and-play priors (PnP) and regularization by denoising (RED) methods have become widely used for solving inverse problems by leveraging pre-trained deep denoisers as image priors. While the empirical imaging performance and the theoretical convergence properties of these algorithms have been widely investigated, their recovery properties have not previously been theoretically analyzed. We address this gap by showing how to establish theoretical recovery guarantees for PnP/RED by assuming that the solution of these methods lies near the fixed-points of a deep neural network. We also pre…
During the past few years, inverse problem formulations of ultrasound beamforming have attracted a growing interest. They usually pose beamforming as a minimization problem of a fidelity term resulting from the measurement model plus a regularization term that enforces a certain class on the resulting image. Herein, we take advantages of alternating direction method of multipliers to propose a flexible framework in which each term is optimized separately. Furthermore, the proposed beamforming formulation is extended to replace the regularization term by a denoising algorithm, based on the rece…
University of California, Los Angeles（加州大学洛杉矶分校）；Texas A&M University（得克萨斯农工大学）
Plug-and-play (PnP) is a non-convex framework that integrates modern denoising priors, such as BM3D or deep learning-based denoisers, into ADMM or other proximal algorithms. An advantage of PnP is that one can use pre-trained denoisers when there is not sufficient data for end-to-end training. Although PnP has been recently studied extensively with great empirical success, theoretical analysis addressing even the most basic question of convergence has been insufficient. In this paper, we theoretically establish convergence of PnP-FBS and PnP-ADMM, without using diminishing stepsizes, under a c…
Beijing Institute of Technology（北京理工大学）；University of Cambridge（剑桥大学）；Shanghai Jiao Tong University（上海交通大学）；Beijing Normal University（北京师范大学）
Plug-and-Play (PnP) is a non-convex optimization framework that combines proximal algorithms, for example, the alternating direction method of multipliers (ADMM), with advanced denoising priors. Over the past few years, great empirical success has been obtained by PnP algorithms, especially for the ones that integrate deep learning-based denoisers. However, a key challenge of PnP approaches is the need for manual parameter tweaking as it is essential to obtain high-quality results across the high discrepancy in imaging conditions and varying scene content. In this work, we present a class of t…
Analysis and Synthesis Denoisers for Forward-Backward Plug-and-Play Algorithms
Laboratoire Interdisciplinaire des Sciences du Numériques, Inria, Université Paris-Saclay, CNRS, Gif-sur-Yvette, France（跨学科数字科学实验室，法国国家信息与自动化研究所，巴黎-萨克雷大学，法国国家科学研究中心，法国吉夫-sur-伊夫特）；Inria, Université Paris-Saclay, CEA, Palaiseau, France（法国国家信息与自动化研究所，巴黎-萨克雷大学，法国原子能委员会，法国帕莱索）；School of Mathematics and Computer Sciences and School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, UK（数学与计算机科学学院和工程与物理科学学院，赫里奥特-瓦特大学，英国爱丁堡）；Maxwell Institute for Mathematical Sciences, Edinburgh, UK（数学科学麦克斯韦研究所，英国爱丁堡）
We propose a simple, interpretable framework for solving a wide range of image reconstruction problems such as denoising and deconvolution. Given a corrupted input image, the model synthesizes a spatially varying linear filter which, when applied to the input image, reconstructs the desired output. The model parameters are learned using supervised or self-supervised training. We test this model on three tasks: non-uniform motion blur removal, lossy-compression artifact reduction and single image super resolution. We demonstrate that our model substantially outperforms state-of-the-art methods …
Plug-and-play priors (PnP) is an image reconstruction framework that uses an image denoiser as an imaging prior. Unlike traditional regularized inversion, PnP does not require the prior to be expressible in the form of a regularization function. This flexibility enables PnP algorithms to exploit the most effective image denoisers, leading to their state-of-the-art performance in various imaging tasks. In this paper, we propose a new denoiser scaling technique to explicitly control the amount of PnP regularization. Traditionally, the performance of PnP algorithms is controlled via intrinsic par…
Plug-and-play (PnP) method is a recent paradigm for image regularization, where the proximal operator (associated with some given regularizer) in an iterative algorithm is replaced with a powerful denoiser. Algorithmically, this involves repeated inversion (of the forward model) and denoising until convergence. Remarkably, PnP regularization produces promising results for several restoration applications. However, a fundamental question in this regard is the theoretical convergence of the PnP iterations, since the algorithm is not strictly derived from an optimization framework. This question …
Iterative denoising algorithms (IDAs) have been tremendously successful in a range of linear inverse problems arising in signal and image processing. The classic instance of this is the famous Iterative Soft-Thresholding Algorithm (ISTA), based on soft-thresholding of wavelet coefficients. More modern approaches to IDAs replace soft-thresholding with a black-box denoiser, such as BM3D or a learned deep neural network denoiser. These are often referred to as ``plug-and-play" (PnP) methods because, in principle, an off-the-shelf denoiser can be used for a variety of different inverse problems. T…
Bell Labs（贝尔实验室）；Massachusetts Institute of Technology（麻省理工学院）；Tsinghua University（清华大学）
We consider the reconstruction problem of video snapshot compressive imaging (SCI), which captures high-speed videos using a low-speed 2D sensor (detector). The underlying principle of SCI is to modulate sequential high-speed frames with different masks and then these encoded frames are integrated into a snapshot on the sensor and thus the sensor can be of low-speed. On one hand, video SCI enjoys the advantages of low-bandwidth, low-power and low-cost. On the other hand, applying SCI to large-scale problems (HD or UHD videos) in our daily life is still challenging and one of the bottlenecks li…
Technion Israel Institute of Technology（以色列理工学院）；Google Research（谷歌研究院）
Inverse problems in image processing are typically cast as optimization tasks, consisting of data-fidelity and stabilizing regularization terms. A recent regularization strategy of great interest utilizes the power of denoising engines. Two such methods are the Plug-and-Play Prior (PnP) and Regularization by Denoising (RED). While both have shown state-of-the-art results in various recovery tasks, their theoretical justification is incomplete. In this paper, we aim to bridge between RED and PnP, enriching the understanding of both frameworks. Towards that end, we reformulate RED as a convex op…
New York University（纽约大学）；Washington University in St. Louis（圣路易斯华盛顿大学）；Tandon School of Engineering（坦登工程学院）；Department of Electrical and Computer Engineering（电子与计算机工程系）；Department of Computer Science and Engineering（计算机科学与工程系）；Department of Electrical and Systems Engineering（电气与系统工程系）
The past few years have seen a surge of activity around integration of deep learning networks and optimization algorithms for solving inverse problems. Recent work on plug-and-play priors (PnP), regularization by denoising (RED), and deep unfolding has shown the state-of-the-art performance of such integration in a variety of applications. However, the current paradigm for designing such algorithms is inherently Euclidean, due to the usage of the quadratic norm within the projection and proximal operators. We propose to broaden this perspective by considering a non-Euclidean setting based on t…
Nanjing University of Posts and Telecommunications（南京邮电大学）；The Chinese University of Hong Kong（香港中文大学）
The Retinex model is one of the most representative and effective methods for low-light image enhancement. However, the Retinex model does not explicitly tackle the noise problem, and shows unsatisfactory enhancing results. In recent years, due to the excellent performance, deep learning models have been widely used in low-light image enhancement. However, these methods have two limitations: i) The desirable performance can only be achieved by deep learning when a large number of labeled data are available. However, it is not easy to curate massive low/normal-light paired data; ii) Deep learni…
Deep-learning-based hyperspectral image (HSI) restoration methods have gained great popularity for their remarkable performance but often demand expensive network retraining whenever the specifics of task changes. In this paper, we propose to restore HSIs in a unified approach with an effective plug-and-play method, which can jointly retain the flexibility of optimization-based methods and utilize the powerful representation capability of deep neural networks. Specifically, we first develop a new deep HSI denoiser leveraging gated recurrent convolution units, short- and long-term skip connecti…
East China Normal University（华东师范大学）；The University of Hong Kong（香港大学）
Aiming at high-dimensional (HD) data acquisition and analysis, snapshot compressive imaging (SCI) obtains the 2D compressed measurement of HD data with optical imaging systems and reconstructs HD data using compressive sensing algorithms. While the Plug-and-Play (PnP) framework offers an emerging solution to SCI reconstruction, its intrinsic denoising process is still a challenging problem. Unfortunately, existing denoisers in the PnP framework either suffer limited performance or require extensive training data. In this paper, we propose an efficient and effective shallow-learning-based algor…
