We present a data-driven approach to compensate for optical aberration in calibration-free quantitative phase imaging (QPI). Unlike existing methods that require additional measurements or a background region to correct aberrations, we exploit deep learning techniques to model the physics of aberration in an imaging system. We demonstrate the generation of a single-shot aberration-corrected field image by using a U-net-based deep neural network that learns a translation between an optical field with aberrations and an aberration-corrected field. The high fidelity of our method is demonstrated on 2D and 3D QPI measurements of various confluent eukaryotic cells, benchmarking against the conventional method using background subtractions.
Coordinate-based Speed of Sound Recovery for Aberration-Corrected Photoacoustic Computed Tomography
Northwestern University(西北大学);California Institute of Technology(加州理工学院);Tsinghua University(清华大学);NSF-Simons AI Institute for the Sky (SkAI)(NSF-模拟斯通AI天空研究所(SkAI))
Quantitative Jones matrix imaging using vectorial Fourier ptychography
本文提出了一种显微成像技术,使用可变角度照明恢复复杂的偏振特性的标本在高分辨率和大视场。该方法扩展了傅立叶重叠关联成像,这是一种基于合成孔径的成像方法,可以通过无相位测量来提高分辨率,以额外考虑光的矢量性质。在使用配备有LED照明阵列和两个偏振器的标准显微镜获取图像后,我们的矢量傅立叶重叠关联(vFP)算法求解了每个解析空间位置处感兴趣的各向异性样本的复杂2x2琼斯矩阵。我们引入了一个新的顺序高斯-牛顿为基础的求解器,另外联合估计和消除偏振相关的成像系统像差。我们证明了有效的vFP性能,通过生成大面积(29 mm $^2$),高分辨率(1.24 $μ$ m全间距)的样品吸收,相位,取向,二向衰减和延迟的各种校准样品和生物标本的重建。
CalibFPA: A Focal Plane Array Imaging System based on Online Deep-Learning Calibration
ASELSAN(ASELSAN公司);Nanodev Scientific(Nanodev Scientific公司);Ostim Technical University(奥斯蒂姆技术大学);National Magnetic Resonance Research Center (UMRAM)(国家磁共振研究中心(UMRAM));Bilkent University(比尔肯特大学)