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arXiv 2006.16155math.AP
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细胞极化模型中的抛物型自由边界问题

A parabolic free boundary problem arising in a model of cell polarization

Anna Logioti, Barbara Niethammer, Matthias Röger, Juan J. L. Velázquez

摘要:

外部信号的放大是生物细胞方向感测的关键步骤。我们考虑一个简单的模型的响应依赖于时间的信号,这是以前提出的最后三个作者。该模型由体-表面反应-扩散模型组成。我们证明了在一个适当的渐近极限系统收敛到一个体表面抛物障碍型问题。对于这个模型和减少到一个非局部表面方程,我们显示了一个L1收缩属性,并在时间常数信号的情况下,稳定的稳态。

英文摘要:

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model consists of a bulk-surface reaction-diffusion model. We prove that in a suitable asymptotic limit the system converges to a bulk-surface parabolic obstacle type problem. For this model and a reduction to a nonlocal surface equation we show an L1-contraction property and, in the case of time-constant signals, the stability of stationary states.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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