石墨烯基纳米分子通讯接收器的制备与微流控分析
Graphene-based Nanoscale Molecular Communication Receiver: Fabrication and Microfluidic Analysis
摘要：
生物启发分子通信（MC），其中分子用于传输信息，是实现纳米物联网（IoNT）的最有前途的技术，这要归功于其固有的生物相容性，能源效率和生理相关环境中的可靠性。尽管大量的理论工作，关于MC，缺乏实际的微/纳米MC设备和MC测试平台，导致研究人员作出过于简化的假设的影响的信道条件和物理架构的实际收发器在开发理论模型和设计的MC通信方法。另一方面，MC提出了独特的挑战，从高度复杂的，非线性的，随时间变化的信道特性，不能总是解决传统的信息和通信工具和技术（ICT）。因此，现有的MC方法的可靠性，这主要是采用从电磁通信和实际测试台验证，是非常值得怀疑的。作为消除这种差异的第一步，在这项研究中，我们报告了基于石墨烯场效应晶体管生物传感器的纳米级MC接收器的制造。我们在定制设计的微流控MC系统中进行ICT表征，并将信息编码到单链DNA分子的浓度中。这个实验平台是第一个实际实现的微/纳米MC系统与纳米MC接收器，并可以作为一个测试平台，开发现实的MC方法和IoNT应用。
英文摘要：
Bio-inspired molecular communications (MC), where molecules are used to transfer information, is the most promising technique to realise the Internet of Nano Things (IoNT), thanks to its inherent biocompatibility, energy-efficiency, and reliability in physiologically-relevant environments. Despite a substantial body of theoretical work concerning MC, the lack of practical micro/nanoscale MC devices and MC testbeds has led researchers to make overly simplifying assumptions about the implications of the channel conditions and the physical architectures of the practical transceivers in developing theoretical models and devising communication methods for MC. On the other hand, MC imposes unique challenges resulting from the highly complex, nonlinear, time-varying channel properties that cannot be always tackled by conventional information and communication tools and technologies (ICT). As a result, the reliability of the existing MC methods, which are mostly adopted from electromagnetic communications and not validated with practical testbeds, is highly questionable. As the first step to remove this discrepancy, in this study, we report on the fabrication of a nanoscale MC receiver based on graphene field-effect transistor biosensors. We perform its ICT characterisation in a custom-designed microfluidic MC system with the information encoded into the concentration of single-stranded DNA molecules. This experimental platform is the first practical implementation of a micro/nanoscale MC system with nanoscale MC receivers, and can serve as a testbed for developing realistic MC methods and IoNT applications.
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