Retinal imaging serves as a valuable tool for diagnosis of various diseases. However, reading retinal images is a difficult and time-consuming task even for experienced specialists. The fundamental step towards automated retinal image analysis is vessel segmentation and artery/vein classification, which provide various information on potential disorders. To improve the performance of the existing automated methods for retinal image analysis, we propose a two-step vessel classification. We adopt a UNet-based model, SeqNet, to accurately segment vessels from the background and make prediction on the vessel type. Our model does segmentation and classification sequentially, which alleviates the problem of label distribution bias and facilitates training. To further refine classification results, we post-process them considering the structural information among vessels to propagate highly confident prediction to surrounding vessels. Our experiments show that our method improves AUC to 0.98 for segmentation and the accuracy to 0.92 in classification over DRIVE dataset.
Accurate measurements of abnormalities like Artery-Vein ratio and tortuosity in fundus images is an actively researched task. Most of the research seems to compute such features independently. However, in this work, we have devised a fully automated technique to measure any vascular abnormalities. This paper is a follow-up paper on vessel topology estimation and extraction, we use the extracted topology to perform A-V state-of-the-art Artery-Vein classification, AV ratio calculation, and vessel tortuosity measurement, all fully automated. Existing techniques tend to only work on the partial re…
Deep learning-driven pulmonary artery and vein segmentation reveals demography-associated vasculature anatomical differences
King Abdullah University of Science and Technology (KAUST)(阿卜杜拉国王科技大学);The First Affiliated Hospital of Harbin Medical University(哈尔滨医科大学附属第一医院);Northeast Forestry University(东北林业大学);The Fourth Hospital of Harbin Medical University(哈尔滨医科大学附属第四医院);China-Japan Friendship Hospital(中日友好医院);Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School(南京大学医学院附属南京鼓楼医院);Renji Hospital, School of Medicine, Shanghai Jiao Tong University(上海交通大学医学院附属仁济医院)
School of Informatics, Xiamen University(厦门大学信息学院)
Retinal artery/vein (A/V) classification is a critical technique for diagnosing diabetes and cardiovascular diseases. Although deep learning based methods achieve impressive results in A/V classification, their performances usually degrade severely when being directly applied to another database, due to the domain shift, e.g., caused by the variations in imaging protocols. In this paper, we propose a novel vessel-mixing based consistency regularization framework, for cross-domain learning in retinal A/V classification. Specially, to alleviate the severe bias to source domain, based on the labe…
We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very challenging because vessels cross each other in a 2D image, obscuring their true paths. We quantitatively validated the usefulness of our extraction method by using it to achieve comparable state-of-the-art results in retinal artery-vein classification. Our proposed approach works as follows: We first segment the retinal vessels using our previously developed sta…
Institute of Medical Robotics, Shanghai Jiao Tong University(上海交通大学医学机器人研究所);School of Computer Science and Technology, Guizhou University(贵州大学计算机科学与技术学院);Shanghai Chest Hospital, Shanghai Jiao Tong University(上海交通大学附属胸科医院);Université de Lyon, INSA Lyon, CREATIS, CNRS, INSERM(里昂大学、里昂国立应用科学学院、CREATIS实验室、法国国家科学研究中心、法国国家健康与医学研究院)
Training convolutional neural networks (CNNs) for segmentation of pulmonary airway, artery, and vein is challenging due to sparse supervisory signals caused by the severe class imbalance between tubular targets and background. We present a CNNs-based method for accurate airway and artery-vein segmentation in non-contrast computed tomography. It enjoys superior sensitivity to tenuous peripheral bronchioles, arterioles, and venules. The method first uses a feature recalibration module to make the best use of features learned from the neural networks. Spatial information of features is properly i…
Force Sensing Guided Artery-Vein Segmentation via Sequential Ultrasound Images
Institute of Automation, Chinese Academy of Sciences(中国科学院自动化研究所);School of Artificial Intelligence, University of Chinese Academy of Sciences(中国科学院大学人工智能学院);Centre for Artificial Intelligence and Robotics, HK Institute of Science & Innovation, Chinese Academy of Sciences(中国科学院香港创新研究院人工智能与机器人中心);City University of Hong Kong(香港城市大学)
Objective Automatic artery/vein (A/V) segmentation from fundus images is required to track blood vessel changes occurring with many pathologies including retinopathy and cardiovascular pathologies. One of the clinical measures that quantifies vessel changes is the arterio-venous ratio (AVR) which represents the ratio between artery and vein diameters. This measure significantly depends on the accuracy of vessel segmentation and classification into arteries and veins. This paper proposes a fast, novel method for semantic A/V segmentation combining deep learning and graph propagation. Methods A …
Youtu Lab, Tencent(腾讯优图实验室);School of Information Science and Engineering, Xiamen University(厦门大学信息科学与工程学院)
Retinal artery/vein (A/V) classification plays a critical role in the clinical biomarker study of how various systemic and cardiovascular diseases affect the retinal vessels. Conventional methods of automated A/V classification are generally complicated and heavily depend on the accurate vessel segmentation. In this paper, we propose a multi-task deep neural network with spatial activation mechanism that is able to segment full retinal vessel, artery and vein simultaneously, without the pre-requirement of vessel segmentation. The input module of the network integrates the domain knowledge of w…
Fuzhou University(福州大学);Fujian Medical University Union Hospital(福建医科大学附属协和医院)
With the development of medical computer-aided diagnostic systems, pulmonary artery-vein(A/V) separation plays a crucial role in assisting doctors in preoperative planning for lung cancer surgery. However, distinguishing arterial from venous irrigation in chest CT images remains a challenge due to the similarity and complex structure of the arteries and veins. We propose a novel method for automatic separation of pulmonary arteries and veins from chest CT images. The method consists of three parts. First, global connection information and local feature information are used to construct a compl…
Henan University of Chinese Medicine(河南中医药大学);Beijing University of Posts and Telecommunications(北京邮电大学);Institute of Automation, Chinese Academy of Sciences(中国科学院自动化研究所)
In recent years, deep convolution neural networks (DCNNs) have achieved great prospects in coronary artery vessel segmentation. However, it is difficult to deploy complicated models in clinical scenarios since high-performance approaches have excessive parameters and high computation costs. To tackle this problem, we propose \textbf{LightVessel}, a Similarity Knowledge Distillation Framework, for lightweight coronary artery vessel segmentation. Primarily, we propose a Feature-wise Similarity Distillation (FSD) module for semantic-shift modeling. Specifically, we calculate the feature similarit…
Retinal artery/vein (A/V) classification lays the foundation for the quantitative analysis of retinal vessels, which is associated with potential risks of various cardiovascular and cerebral diseases. The topological connection relationship, which has been proved effective in improving the A/V classification performance for the conventional graph based method, has not been exploited by the deep learning based method. In this paper, we propose a Topology Ranking Generative Adversarial Network (TR-GAN) to improve the topology connectivity of the segmented arteries and veins, and further to boost…
University College London(伦敦大学学院);UCL(伦敦大学学院);NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology(英国国家健康研究所摩尔菲尔德眼科医院NHS基金会信托与伦敦大学学院眼科研究所生物医学研究中心);Wellcome/EPSRC Centre for Interventional and Surgical Sciences(惠康/英国工程与物理科学研究委员会介入与外科科学中心)
Estimating clinically-relevant vascular features following vessel segmentation is a standard pipeline for retinal vessel analysis, which provides potential ocular biomarkers for both ophthalmic disease and systemic disease. In this work, we integrate these clinical features into a novel vascular feature optimised loss function (VAFO-Loss), in order to regularise networks to produce segmentation maps, with which more accurate vascular features can be derived. Two common vascular features, vessel density and fractal dimension, are identified to be sensitive to intra-segment misclassification, wh…
Carotid artery vessel wall thickness measurement is an essential step in the monitoring of patients with atherosclerosis. This requires accurate segmentation of the vessel wall, i.e., the region between an artery's lumen and outer wall, in black-blood magnetic resonance (MR) images. Commonly used convolutional neural networks (CNNs) for semantic segmentation are suboptimal for this task as their use does not guarantee a contiguous ring-shaped segmentation. Instead, in this work, we cast vessel wall segmentation as a multi-task regression problem in a polar coordinate system. For each carotid a…
Improve Retinal Artery/Vein Classification via Channel Couplin
Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China(北京大学医学部医学技术研究所);Department of Biomedical Engineering, Peking University, Beijing, China(北京大学生物医学工程系);National Biomedical Imaging Center, Peking University, Beijing, China(北京大学国家生物医学成像中心);Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology(佐治亚理工学院生物医学工程系);Emory University, Atlanta, GA, USA(埃默里大学)
4D-CAT: Synthesis of 4D Coronary Artery Trees from Systole and Diastole
School of Computer Science and Engineering, Sun Yat-sen University(中山大学计算机科学与工程学院);Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine(上海交通大学医学院附属仁济医院);Punan Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine(上海交通大学医学院附属仁济医院浦南分院)
Imaging technology center, Fujifilm corporation(富士胶片株式会社影像技术中心);Center for Artificial Intelligence Research, University of Tsukuba(筑波大学人工智能研究中心);Department of Computer science and engineering, Waseda university(早稻田大学计算机科学与工程系)
Reconstructing Portal Vein and Hepatic Vein trees from contrast enhanced abdominal CT scans is a prerequisite for preoperative liver surgery simulation. Existing deep learning based methods treat vascular tree reconstruction as a semantic segmentation problem. However, vessels such as hepatic and portal vein look very similar locally and need to be traced to their source for robust label assignment. Therefore, semantic segmentation by looking at local 3D patch results in noisy misclassifications. To tackle this, we propose a novel multi-task deep learning architecture for vessel tree reconstru…
Artery and vein (AV) classification of retinal images is a key to necessary tasks, such as automated measurement of arteriolar-to-venular diameter ratio (AVR). This paper comprehensively reviews the state-of-the art in AV classification methods. To improve on previous methods, a new Local Bi- nary Pattern-based method (LBP) is proposed. Beside its simplicity, LBP is robust against low contrast and low quality fundus images; and it helps the process by including additional AV texture and shape information. Experimental results compare the performance of the new method with the state-of-the art;…
Self-adaptive vision-language model for 3D segmentation of pulmonary artery and vein
National Clinical Research Center for Cancer/Cancer Hospital Shenzhen Hospital(国家癌症临床研究中心/肿瘤医院深圳医院);Key Laboratory of System Software (Chinese Academy of Sciences)(系统软件重点实验室(中国科学院));State Key Laboratory of Computer Science(计算机科学国家重点实验室);Institute of Software, Chinese Academy of Sciences(中国科学院软件研究所);Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences(中国科学院大学杭州高等研究院);School of Computer Science and Engineering, Beihang University(北京航空航天大学计算机科学与工程学院);Guangzhou Jiayi Software Technology Co., Ltd.(广州嘉益软件科技有限公司);R&D Center, Guangxi Huayi Artificial Intelligence Medical Technology Co., Ltd(广西华奕人工智能医疗科技有限公司研发中心);Department of Computer Science, University of Exeter(埃克塞特大学计算机科学系);Department of Cardiovascular & Metabolic Medicine, University of Liverpool(利物浦大学心血管与代谢医学系)
Learning Wall Segmentation in 3D Vessel Trees using Sparse Annotations
Institute of Computer-Assisted Cardiovascular Medicine, Charité - Universitätsmedizin Berlin(柏林夏里特医学院计算机辅助心血管医学研究所);Fraunhofer MEVIS(弗劳恩霍夫梅维斯研究所);DZHK (German Centre for Cardiovascular Research)(德国心血管研究中心);Physikalisch-Technische Bundesanstalt(德国联邦物理技术研究院);Medical Center—University of Freiburg, University of Freiburg(弗莱堡大学医学中心、弗莱堡大学)
Robust automatic brain vessel segmentation in 3D CTA scans using dynamic 4D-CTA data
Northeastern University, Boston, USA(东北大学);Washington University in St. Louis, St, Louis, USA(华盛顿大学);Dana-Farber Cancer Institute, Boston, USA(达纳-法伯癌症研究所);Brigham and Women's Hospital, Boston, USA(布里奇曼和妇女医院);Harvard Medical School, Boston, USA(哈佛医学院)
A topology-preserving three-stage framework for fully-connected coronary artery extraction
Center for Digital Media Computing, School of Film, School of Informatics, Xiamen University(厦门大学电影学院、信息学院数字媒体计算中心);Institute of Artificial Intelligence, Xiamen University(厦门大学人工智能研究院);Peking Union Medical College Hospital(北京协和医院);Shanghai United Imaging Intelligence Co., Ltd.(上海联影智能医疗科技有限公司);City University of Hong Kong(香港城市大学);Shanghai Clinical Research and Trial Center(上海临床研究与试验中心)
Shanghai Jiao Tong University(上海交通大学);Peking Union Medical College Hospital(北京协和医院)
The segmentation of coronary arteries by convolutional neural network is promising yet requires a large amount of labor-intensive manual annotations. Transferring knowledge from retinal vessels in widely-available public labeled fundus images (FIs) has a potential to reduce the annotation requirement for coronary artery segmentation in X-ray angiograms (XAs) due to their common tubular structures. However, it is challenged by the cross-anatomy domain shift due to the intrinsically different vesselness characteristics in different anatomical regions under even different imaging protocols. To so…
Carotid Artery Plaque Analysis in 3D Based on Distance Encoding in Mesh Representations
Institute of Computer-Assisted Cardiovascular Medicine(计算机辅助心血管医学研究所);Deutsches Herzzentrum der Charité(Charité心脏中心);Fraunhofer MEVIS(弗劳恩霍夫医学影像研究所);DZHK (German Centre for Cardiovascular Research)(德国心血管研究中心);Physikalisch-Technische Bundesanstalt (PTB)(物理技术联邦机构)
We propose a novel deep-learning-based system for vessel segmentation. Existing methods using CNNs have mostly relied on local appearances learned on the regular image grid, without considering the graphical structure of vessel shape. To address this, we incorporate a graph convolutional network into a unified CNN architecture, where the final segmentation is inferred by combining the different types of features. The proposed method can be applied to expand any type of CNN-based vessel segmentation method to enhance the performance. Experiments show that the proposed method outperforms the cur…
Centro de Investigación CITIC(CITIC研究中心);Universidade da Coruña(拉科鲁尼亚大学);Instituto de Investigación Biomédica de A Coruña (INIBIC)(拉科鲁尼亚生物医学研究所(INIBIC))
The study of the retinal vasculature is a fundamental stage in the screening and diagnosis of many diseases. A complete retinal vascular analysis requires to segment and classify the blood vessels of the retina into arteries and veins (A/V). Early automatic methods approached these segmentation and classification tasks in two sequential stages. However, currently, these tasks are approached as a joint semantic segmentation task, as the classification results highly depend on the effectiveness of the vessel segmentation. In that regard, we propose a novel approach for the simultaneous segmentat…
Tsinghua University(清华大学);Beijing Anzhen Hospital, Capital Medical University(首都医科大学附属北京安贞医院);The First Affiliated Hospital of Zhengzhou University(郑州大学第一附属医院)
Coronary angiography is an indispensable assistive technique for cardiac interventional surgery. Segmentation and extraction of blood vessels from coronary angiography videos are very essential prerequisites for physicians to locate, assess and diagnose the plaques and stenosis in blood vessels. This article proposes a new video segmentation framework that can extract the clearest and most comprehensive coronary angiography images from a video sequence, thereby helping physicians to better observe the condition of blood vessels. This framework combines a 3D convolutional layer to extract spati…
HTC-SGA Former: A Hybrid Transformer-CNN Network with Self-Guided Attention and a New Boundary-Weighted Adaptive Loss for Coronary DSA Vessel Segmentation
Shenzhen Institutes of Advanced Technology (SIAT)(深圳先进技术研究院);University of Chinese Academy of Sciences (UCAS)(中国科学院大学);Department of Biomedical Engineering and Systems, Faculty of Engineering(工程学院生物医学工程与系统系);Cairo University(开罗大学)
RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation
The University of Queensland(昆士兰大学);University of Technology Sydney(悉尼科技大学);Australian National University(澳大利亚国立大学);University of New South Wales(新南威尔士大学);Victoria University(维多利亚大学);Deakin University(迪肯大学)
Peripancreatic vessel segmentation and anatomical labeling play extremely important roles to assist the early diagnosis, surgery planning and prognosis for patients with pancreatic tumors. However, most current techniques cannot achieve satisfactory segmentation performance for peripancreatic veins and usually make predictions with poor integrity and connectivity. Besides, unsupervised labeling algorithms cannot deal with complex anatomical variation while fully supervised methods require a large number of voxel-wise annotations for training, which is very labor-intensive and time-consuming. T…
ImageCAS-X: a dataset and benchmark for coronary artery segmentation and centerline extraction in coronary CT angiography
DTU Compute, Technical University of Denmark(丹麦技术大学DTU计算学院);Cardiovascular Research Unit, Copenhagen University Hospital – Rigshospitalet(哥本哈根大学医院——国立医院心血管研究科)
Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR)(新加坡科技研究局生物信息学研究所);Hwa Chong Institution (College)(华侨中学(高中部));National Heart Centre Singapore(新加坡国家心脏中心);Duke-NUS Medical School(杜克-新加坡国立大学医学院);School of Computing, National University of Singapore(新加坡国立大学计算学院);Singapore Eye Research Institute (SERI)(新加坡眼科研究所);Rehabilitation Research Institute of Singapore(新加坡康复研究所);Institute of Bioengineering and Nanotechnology, A*STAR(新加坡科技研究局生物工程与纳米技术研究所)
The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies have attempted to automate this process, but few have demonstrated an integrated suite of algorithms for the end-to-end analysis of angiograms. We report an automated analysis pipeline based on deep learning to rapidly and objectively assess coronary angiograms, highlight coronary vessels of interest, and quantify potential stenosis. We propose a 3-stage auto…
Coronary Artery Segmentation and Vessel-Type Classification in X-Ray Angiography
School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran(计算机科学学院,基础科学研究所(IPM),德黑兰,伊朗);Department of Physics, Shahid Beheshti University, Tehran, Iran(物理系,肖德·贝赫什提大学,德黑兰,伊朗);Brain Mapping Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran(脑图谱研究中心,肖德·贝赫什提医学科学大学,德黑兰,伊朗);Gilan University of Medical Sciences, Rasht, Gilan, Iran(加利良医学科学大学,拉什特,加利良,伊朗);Department of Physics, Simon Fraser University, Burnaby, Canada(物理系,西蒙·弗雷泽大学,本比,加拿大);Fatemeh Zahra Hospital, Alborz University of Medical Sciences, Eshtehard, Iran(法特梅·扎拉医院,阿尔博兹医学科学大学,埃什泰尔德,伊朗);Rajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, Iran(拉贾伊心血管医学与研究学院,伊朗医学科学大学,德黑兰,伊朗)
ArteryX: A Reliable End-to-End Toolbox for Standardized Intracranial Artery Feature Extraction from 3D TOF-MRA
Department of Neurology, University of Rochester(罗切斯特大学神经科部);Department of Physics, University of Rochester(罗切斯特大学物理系);Department of Imaging Sciences, University of Rochester(罗切斯特大学影像科学系);Department of Electrical & Computer Engineering, University of Rochester(罗切斯特大学电气与计算机工程系);Department of Biomedical Engineering, University of Rochester(罗切斯特大学生物医学工程系)
In this report we want to present our method and results for the Carotid Artery Vessel Wall Segmentation Challenge. We propose an image-based pipeline utilizing the U-Net architecture and location priors to solve the segmentation problem at hand.
INESC-ID(里斯本系统与计算机工程研究所);Instituto Superior Técnico, University of Lisbon(里斯本大学高等技术学院);Lisbon School of Medicine, University of Lisbon(里斯本大学里斯本医学院)
Coronary X-ray angiography is a crucial clinical procedure for the diagnosis and treatment of coronary artery disease, which accounts for roughly 16% of global deaths every year. However, the images acquired in these procedures have low resolution and poor contrast, making lesion detection and assessment challenging. Accurate coronary artery segmentation not only helps mitigate these problems, but also allows the extraction of relevant anatomical features for further analysis by quantitative methods. Although automated segmentation of coronary arteries has been proposed before, previous approa…
We present a fully automated method for top-down segmentation of the pulmonary arterial tree in low-dose thoracic CT images. The main basal pulmonary arteries are identified near the lung hilum by searching for candidate vessels adjacent to known airways, identified by our previously reported airway segmentation method. Model cylinders are iteratively fit to the vessels to track them into the lungs. Vessel bifurcations are detected by measuring the rate of change of vessel radii, and child vessels are segmented by initiating new trackers at bifurcation points. Validation is accomplished using …
University Medical Center Utrecht(乌得勒支大学医学中心);Utrecht University(乌得勒支大学)
Coronary artery centerline extraction in cardiac CT angiography (CCTA) images is a prerequisite for evaluation of stenoses and atherosclerotic plaque. We propose an algorithm that extracts coronary artery centerlines in CCTA using a convolutional neural network (CNN). A 3D dilated CNN is trained to predict the most likely direction and radius of an artery at any given point in a CCTA image based on a local image patch. Starting from a single seed point placed manually or automatically anywhere in a coronary artery, a tracker follows the vessel centerline in two directions using the predictions…
DSCA: A Digital Subtraction Angiography Sequence Dataset and Spatio-Temporal Model for Cerebral Artery Segmentation
Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences(中国科学院宁波材料技术与工程研究所);School of Cyber Science and Engineering, Ningbo University of Technology(宁波工程学院网络空间安全学院);Shandong Artificial Intelligence Institute, Qilu University of Technology(齐鲁工业大学山东省人工智能研究院);School of Intelligence Science and Technology, Nanjing University(南京大学智能科学与技术学院);Erasmus MC, University Medical Center(伊拉斯姆斯大学医学中心);Department of Biomedical Engineering, Eindhoven University of Technology(埃因霍温理工大学生物医学工程系);First Affiliated Hospital of Zhengzhou University(郑州大学第一附属医院)
Nara Institute of Science and Technology(奈良先端科学技术大学院大学);Technische Universität München(慕尼黑工业大学);National Cerebral and Cardiovascular Center(国立循环器病研究中心)
Purpose: The motion of the common carotid artery tissue layers along the vessel axis during the cardiac cycle, observed in ultrasound imaging, is associated with the presence of established cardiovascular risk factors. However, the vast majority of the methods are based on the tracking of a single point, thus failing to capture the overall motion of the entire arterial wall. The aim of this work is to introduce a motion tracking framework able to simultaneously extract the trajectory of a large collection of points spanning the entire exploitable width of the image. Method: The longitudinal mo…
University of California, Los Angeles(加利福尼亚大学洛杉矶分校);Stein Eye Institute(斯坦眼科研究所);VoxelCloud, Inc.(体素云公司)
The retinal vasculature provides important clues in the diagnosis and monitoring of systemic diseases including hypertension and diabetes. The microvascular system is of primary involvement in such conditions, and the retina is the only anatomical site where the microvasculature can be directly observed. The objective assessment of retinal vessels has long been considered a surrogate biomarker for systemic vascular diseases, and with recent advancements in retinal imaging and computer vision technologies, this topic has become the subject of renewed attention. In this paper, we present a novel…
University of Maryland, College Park(马里兰大学帕克分校);Intuitive Surgical, Inc(直观外科公司)
Semantic image segmentation plays an important role in modeling patient-specific anatomy. We propose a convolution neural network, called Kid-Net, along with a training schema to segment kidney vessels: artery, vein and collecting system. Such segmentation is vital during the surgical planning phase in which medical decisions are made before surgical incision. Our main contribution is developing a training schema that handles unbalanced data, reduces false positives and enables high-resolution segmentation with a limited memory budget. These objectives are attained using dynamic weighting, ran…