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arXiv 2602.00391cs.CV

使用动态4D-CTA数据进行3D CTA扫描中鲁棒的自动脑血管分割

Robust automatic brain vessel segmentation in 3D CTA scans using dynamic 4D-CTA data

Northeastern University, Boston, USA(东北大学);Washington University in St. Louis, St, Louis, USA(华盛顿大学);Dana-Farber Cancer Institute, Boston, USA(达纳-法伯癌症研究所);Brigham and Women's Hospital, Boston, USA(布里奇曼和妇女医院);Harvard Medical School, Boston, USA(哈佛医学院)

Alberto Mario Ceballos-Arroyo, Shrikanth M. Yadav, Chu-Hsuan Lin, Jisoo Kim, Geoffrey S. Young, Lei Qin, Huaizu Jiang

AI总结:

本文提出了一种基于动态4D-CTA数据的鲁棒自动脑血管分割方法,通过扩大数据集和增强鲁棒性,提升了分割精度和敏感度。

摘要:

在本研究中,我们开发了一种新的方法,用于使用动态4D-CTA头部扫描来标注大脑血管。通过使用动态CTA采集的多个时间点,我们减去骨骼和软组织以增强动脉和静脉的可视化,从而减少获取手动标注大脑血管所需的努力。然后,我们通过使用动态4D-CTA集合中的多个阶段相同的分割来训练深度学习模型,有效地将我们的数据集扩大了4到5倍,并诱导出对对比阶段的鲁棒性。总共,我们的数据集包含来自25名患者的110张训练图像和来自14名患者的165张测试图像。与两个同样规模的CTA基于大脑血管分割数据集相比,使用我们数据集训练的nnUNet模型在所有血管区域都能实现显著更好的分割效果,与TopBrain数据集相比,动脉的平均mDC为0.846,静脉为0.957。此外,平均定向Hausdorff距离(adHD)和拓扑敏感度(tSens)等指标也反映了相似的趋势:使用我们的数据集导致低误差范围(动脉的adHD为0.304毫米,静脉为0.078)和高敏感度(动脉的tSens为0.877,静脉为0.974),表明在捕捉血管形态方面具有极高的准确性。我们的代码和模型权重可在https://github.com/alceballosa/robust-vessel-segmentation上在线获取。

英文摘要:

In this study, we develop a novel methodology for annotating the brain vasculature using dynamic 4D-CTA head scans. By using multiple time points from dynamic CTA acquisitions, we subtract bone and soft tissue to enhance the visualization of arteries and veins, reducing the effort required to obtain manual annotations of brain vessels. We then train deep learning models on our ground truth annotations by using the same segmentation for multiple phases from the dynamic 4D-CTA collection, effectively enlarging our dataset by 4 to 5 times and inducing robustness to contrast phases. In total, our dataset comprises 110 training images from 25 patients and 165 test images from 14 patients. In comparison with two similarly-sized datasets for CTA-based brain vessel segmentation, a nnUNet model trained on our dataset can achieve significantly better segmentations across all vascular regions, with an average mDC of 0.846 for arteries and 0.957 for veins in the TopBrain dataset. Furthermore, metrics such as average directed Hausdorff distance (adHD) and topology sensitivity (tSens) reflected similar trends: using our dataset resulted in low error margins (adHD of 0.304 mm for arteries and 0.078 for veins) and high sensitivity (tSens of 0.877 for arteries and 0.974 for veins), indicating excellent accuracy in capturing vessel morphology. Our code and model weights are available online at https://github.com/alceballosa/robust-vessel-segmentation

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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