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arXiv 2005.06769stat.APecon.EM
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结合人群和研究数据推断事件发生率

Combining Population and Study Data for Inference on Event Rates

Christoph Rothe

摘要:

本说明考虑的问题进行统计推断的份额的个人在一些亚组的人口经历一些事件。具体的复杂性是需要估计亚组的大小,而经历该事件的个体的数量是已知的。这个问题是由Streeck等人(2020)最近的研究引起的,他们估计了2020年2月中旬经历超级传播事件的德国城镇SARS-CoV-2感染的感染死亡率(IFR)。在他们的情况下,感兴趣的亚组由所有感染的个体组成,事件是由感染引起的死亡。我们澄清问题的精确定义的目标参数在这种情况下,并提出置信区间(CI)的基础上,经典的统计原理,导致良好的覆盖性能。

英文摘要:

This note considers the problem of conducting statistical inference on the share of individuals in some subgroup of a population that experience some event. The specific complication is that the size of the subgroup needs to be estimated, whereas the number of individuals that experience the event is known. The problem is motivated by the recent study of Streeck et al. (2020), who estimate the infection fatality rate (IFR) of SARS-CoV-2 infection in a German town that experienced a super-spreading event in mid-February 2020. In their case the subgroup of interest is comprised of all infected individuals, and the event is death caused by the infection. We clarify issues with the precise definition of the target parameter in this context, and propose confidence intervals (CIs) based on classical statistical principles that result in good coverage properties.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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