Exact analytical channel models for molecular communication via diffusion (MCvD) systems involving multiple fully absorbing receivers (FARs) in a three-dimensional (3- D) medium are hard to obtain due to the mathematical intractability of corresponding diffusion equations. This work, therefore, consider an MCvD system with two spherical FARs in a 3-D diffusion-limited medium and develop several insights using an approximate analytical expression for the hitting probability of information molecule (IM). Further, based on the hitting probability, a novel approximate closed-form analytical expression for the area under the receiver operating characteristic curve (AUC) is derived to analyze the detection performance at each FAR in the presence of other FAR. Finally, simulation results are presented to validate the analytical results using the particle-based and Monte-Carlo simulations and to yield important insights into the MCvD system performance with two FARs
This work considers the problem of flow-induced diffusive molecular communication under various mobility conditions such as (i) both transmitter (TX) and receiver (RX) nanomachines are mobile, (ii) TX is mobile and RX is fixed, and (iii) TX is fixed and RX is mobile. Closed-form expressions for the probability density function (PDF) of the first hitting time under the aforementioned mobile scenarios are derived, by characterizing the movement of the nanomachines and information molecules using Brownian motion with positive drift. The derived PDF expressions are validated through particle-based…
This letter introduces an analytical model that gives the asymptotic cumulative number of molecules absorbed by spherical receivers in a diffusive multiple-input multiple-output (MIMO) molecular communication (MC) system with pointwise transmitters. In the proposed model, the reciprocal effect among the fully absorbing (FA) receivers is described by using the concept of fictitious pointwise negative source of molecules, the best position of which for each spherical receiver being defined by its absorption barycenter. We show that there is an agreement between the proposed asymptotic model and …
Molecular communication is a promising solution to enable intra-body communications among nanomachines. However, malicious and non-cooperative receivers can degrade the performance, compromising these systems' security. Analyzing the communication and security performance of these systems requires accurate channel models. However, such models are not present in the literature. In this work, we develop an analytical framework to derive the hitting probability of a molecule on a fully absorbing receiver (FAR) in the presence of other FARs, which can be either be cooperative or malicious. We firs…
This paper presents a stochastic analysis of the time-variant channel impulse response (CIR) of a three dimensional diffusive mobile molecular communication (MC) system where the transmitter, the absorbing receiver, and the molecules can freely diffuse. In our analysis, we derive the mean, variance, probability density function (PDF), and cumulative distribution function (CDF) of the CIR. We also derive the PDF and CDF of the probability p that a released molecule is absorbed at the receiver during a given time period. The obtained analytical results are employed for the design of drug deliver…
The performance of molecular communication is significantly impacted by the reception process of the messenger molecules. The receptors' size and density, however, have yet to be investigated. In this letter, we analyze the effect of receptor density and size on the signal reception of an absorbing receiver with receptors. The results show that, when the total receptor area is the same, better hitting probability is achieved by using a higher number of relatively small receptors. In addition, deploying receptors, which cover a small percentage of the receiver surface, is able to create an effe…
Molecular communication (MC) can enable the transfer of information between nanomachines using molecules as the information carrier. In MC systems, multiple receiver nanomachines often co-exist in the same communication channel to serve common or different purposes. However, the analytical channel model for a system with multiple fully absorbing receivers (FARs) does not exist in the literature, which is significantly different from the single FAR system due to the mutual influence of FARs. The analytical channel model is essential in analyzing systems with multiple FARs, including MIMO, SIMO,…
Motivated by the numerous healthcare applications of molecular communication (MC) inside blood vessels, this work considers relay/cooperative nanomachine (CN)-assisted mobile MC between a source nanomachine (SN) and a destination nanomachine (DN) where each nanomachine is mobile in a flow-induced diffusive channel. Using the first hitting time model, the impact of an intermediate CN on the performance of the CN-assisted diffusive mobile MC system with fully absorbing receivers is analyzed in the presence of inter-symbol interference, multi-source interference, and counting errors. For this pur…
Diffusive molecular communication (DMC) is one of the most promising approaches for realizing nano-scale communications in biological environments for healthcare applications. In this paper, a DMC system in biological cylindrical environment is considered, inspired by blood vessel structures in the body. The internal surface of the cylinder boundary is assumed to be covered by the biological receptors which may irreversibly react with hitting molecules. Also, information molecules diffusing in the fluid medium are subject to a degradation reaction and flow. The concentration Green's function o…
A molecular communication channel is determined by the received signal. Received signal models form the basis for studies focused on modulation, receiver design, capacity, and coding depend on the received signal models. Therefore, it is crucial to model the number of received molecules until time $t$ analytically. Modeling the diffusion-based molecular communication channel with the first-hitting process is an open issue for a spherical transmitter. In this paper, we utilize the artificial neural networks technique to model the received signal for a spherical transmitter and a perfectly absor…
In this paper an analytical model is introduced to describe the impulse response of the diffusive channel between a pointwise transmitter and a given fully-absorbing (FA) receiver in a molecular communication (MC) system. The presence of neighbouring FA nanomachines in the environment is taken into account by describing them as sources of negative molecules. The channel impulse responses of all the receivers are linked in a system of integral equations. The solution of the system with two receivers is obtained analytically. For a higher number of receivers the system of integral equations is s…
In this paper, we consider molecular communications in one-dimensional flow-induced diffusion channels with a perfectly absorbing receiver. In such channels, the random propagation delay until the molecules are absorbed follows an inverse Gaussian (IG) distribution and is referred to as first hitting time. Knowing the distribution for the difference of the first hitting times of two molecules is very important if the information is encoded by a limited set of molecules and the receiver exploits their arrival time and/or order. Hence, we propose a moment matching approximation by a normal inver…
This paper proposes a novel imperfect transmitter (TX) model, namely the membrane fusion (MF)-based TX, that adopts MF between a vesicle and the TX membrane to release molecules encapsulated within the vesicle. For the MF-based TX, the molecule release probability and the fraction of molecules released from the TX membrane are derived. Incorporating molecular degradation and a fully-absorbing receiver (RX), the channel impulse response (CIR) is derived for two scenarios: 1) Both TX and RX are static, and 2) both TX and RX are diffusion-based mobile. Moreover, a sequence of bits transmitted fro…
A one-dimensional (1-D) anomalous-diffusive molecular communication channel is considered, wherein the devices (transmitter (TX) and receiver (RX)) can move in either direction along the axis. For modeling the anomalous diffusion of information carrying molecules (ICM) as well as that of the TX and RX, the concept of time-scaled Brownian motion is explored. In this context, a novel closed-form expression for the first hitting time density (FHTD) is derived. Further, the derived FHTD is validated through particle-based simulation. For the transmission of binary information, the timing modulatio…
Molecular communication is an emerging paradigm for systems that rely on the release of molecules as information carriers. Communication via molecular diffusion is a popular strategy that is ubiquitous in nature and very fast over distances on the order of a micron or less. Existing closed-form analysis of the diffusion channel impulse response generally assumes that the transmitter is a point source. In this paper, channel impulse responses are derived for spherical transmitters with either a passive or absorbing receiver. The derived channel impulse responses are in closed-form for a one-dim…
In this paper, we present an analytical model for a diffusive molecular communication (MC) system with a reversible adsorption receiver in a fluid environment. The time-varying spatial distribution of the information molecules under the reversible adsorption and desorption reaction at the surface of a bio-receiver is analytically characterized. Based on the spatial distribution, we derive the number of newly-adsorbed information molecules expected in any time duration. Importantly, we present a simulation framework for the proposed model that accounts for the diffusion and reversible reaction.…
Molecular communication often involves coexisting links where certain links may have priority over others. In this work, we consider a system in three-dimensional (3-D) space with two coexisting communication links, each between a point transmitter and fully-absorbing spherical receiver (FAR), where the one link (termed primary) has priority over the second link (termed secondary). The system implements the underlay cognitive-communication strategy for the co-existence of both links, which use the same type of molecules for information transfer. Mutual influence of FARs existing in the same co…
In this paper, we present an analytical framework to derive the performance of a molecular communication system where a transmitter bio-nano-machine (TBN) is communicating with a fully-absorbing spherical receiver bio-nano-machine (RBN) in a diffusive propagation medium in the presence of other TBNs. We assume that transmit bits at each TBN is random and different than transmit bits at other TBNs. We model the TBNs using a marked Poisson point process (PPP) with their locations as points of PPP and transmit symbols as marks. We consider both inter-symbol interference (ISI) and co-channel inter…
