arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2005.00387cs.HCcs.GR
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Bionic Tracking:在虚拟现实中使用眼动追踪来跟踪生物细胞

Bionic Tracking: Using Eye Tracking to Track Biological Cells in Virtual Reality

Ulrik Günther, Kyle I. S. Harrington, Raimund Dachselt, Ivo F. Sbalzarini

摘要:

我们提出了仿生跟踪,一种新的方法来解决生物细胞跟踪问题的眼动追踪在虚拟现实使用商品硬件。使用凝视数据,特别是平滑追踪眼球运动,我们能够跟踪细胞的时间序列的三维体积数据集。跟踪细胞的问题在发育生物学中是普遍存在的,其中每天都要采集大量的体积显微镜数据集,通常包括数百或数千个跨越数小时或数天的时间点。然而,图像数据只是达到目的的一种手段,科学家们通常对细胞轨迹和细胞谱系树的重建感兴趣。在许多时间点上在拥挤的三维空间中可靠地跟踪细胞仍然是一个悬而未决的问题,并且许多当前的方法依赖于繁琐的手动注释和管理。在我们的仿生跟踪方法中,我们用虚拟现实头戴设备中的眼动追踪代替了通常的2D点击注释来跟踪细胞,用户只需在3D空间中用眼睛跟踪细胞即可跟踪它。我们详细介绍了我们方法的交互设计,并解释了用于连接不同时间点的基于图形的算法,同时考虑了遮挡和用户分心。我们使用两个不同的生物数据集的例子来演示我们的细胞跟踪方法。最后,我们报告了一个用户研究与七个细胞跟踪专家,展示了我们的方法比手动点和点击跟踪的好处。

英文摘要:

We present Bionic Tracking, a novel method for solving biological cell tracking problems with eye tracking in virtual reality using commodity hardware. Using gaze data, and especially smooth pursuit eye movements, we are able to track cells in time series of 3D volumetric datasets. The problem of tracking cells is ubiquitous in developmental biology, where large volumetric microscopy datasets are acquired on a daily basis, often comprising hundreds or thousands of time points that span hours or days. The image data, however, is only a means to an end, and scientists are often interested in the reconstruction of cell trajectories and cell lineage trees. Reliably tracking cells in crowded three-dimensional space over many timepoints remains an open problem, and many current approaches rely on tedious manual annotation and curation. In our Bionic Tracking approach, we substitute the usual 2D point-and-click annotation to track cells with eye tracking in a virtual reality headset, where users simply have to follow a cell with their eyes in 3D space in order to track it. We detail the interaction design of our approach and explain the graph-based algorithm used to connect different time points, also taking occlusion and user distraction into account. We demonstrate our cell tracking method using the example of two different biological datasets. Finally, we report on a user study with seven cell tracking experts, demonstrating the benefits of our approach over manual point-and-click tracking.

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