Epidemics of infectious diseases are an important threat to public health and global economies. Yet, the development of prevention strategies remains a challenging process, as epidemics are non-linear and complex processes. For this reason, we investigate a deep reinforcement learning approach to automatically learn prevention strategies in the context of pandemic influenza. Firstly, we construct a new epidemiological meta-population model, with 379 patches (one for each administrative district in Great Britain), that adequately captures the infection process of pandemic influenza. Our model balances complexity and computational efficiency such that the use of reinforcement learning techniques becomes attainable. Secondly, we set up a ground truth such that we can evaluate the performance of the 'Proximal Policy Optimization' algorithm to learn in a single district of this epidemiological model. Finally, we consider a large-scale problem, by conducting an experiment where we aim to learn a joint policy to control the districts in a community of 11 tightly coupled districts, for which no ground truth can be established. This experiment shows that deep reinforcement learning can be used to learn mitigation policies in complex epidemiological models with a large state space. Moreover, through this experiment, we demonstrate that there can be an advantage to consider collaboration between districts when designing prevention strategies.
We study the benefits of reinforcement learning (RL) environments based on agent-based models (ABM). While ABMs are known to offer microfoundational simulations at the cost of computational complexity, we empirically show in this work that their non-deterministic dynamics can improve the generalization of RL agents. To this end, we examine the control of an epidemic SIR environments based on either differential equations or ABMs. Numerical simulations demonstrate that the intrinsic noise in the ABM-based dynamics of the SIR model not only improve the average reward but also allow the RL agent …
Vrije Universiteit Brussel（布鲁塞尔自由大学）；National University of Ireland Galway（爱尔兰国立大学戈尔韦分校）；University of Antwerp（安特卫普大学）；Hasselt University（哈瑟尔特大学）；HU University of Applied Sciences Utrecht（乌得勒支应用科学大学）
Infectious disease outbreaks can have a disruptive impact on public health and societal processes. As decision making in the context of epidemic mitigation is hard, reinforcement learning provides a methodology to automatically learn prevention strategies in combination with complex epidemic models. Current research focuses on optimizing policies w.r.t. a single objective, such as the pathogen's attack rate. However, as the mitigation of epidemics involves distinct, and possibly conflicting criteria (i.a., prevalence, mortality, morbidity, cost), a multi-objective approach is warranted to lear…
In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the economy. On the one hand, the health and safety of the population is the principal consideration for most countries. On the other hand, we cannot ignore the potential for long-term economic damage caused by strict nation-wide lockdowns. In this working paper, we present a quantitative way to compute lockdown decisions for individual cities or regions, while balan…
Reward Engineering for Spatial Epidemic Simulations: A Reinforcement Learning Platform for Individual Behavioral Learning
Department of Computer Science University of British Columbia（计算机科学系，不列颠哥伦比亚大学）；Department of Mathematics and Institute of Applied Mathematics University of British Columbia（数学系和应用数学研究所，不列颠哥伦比亚大学）
Peking University（北京大学）；University of California, Berkeley（加州大学伯克利分校）；Carnegie Mellon University（卡内基梅隆大学）
Microscopic epidemic models are powerful tools for government policy makers to predict and simulate epidemic outbreaks, which can capture the impact of individual behaviors on the macroscopic phenomenon. However, existing models only consider simple rule-based individual behaviors, limiting their applicability. This paper proposes a deep-reinforcement-learning-powered microscopic model named Microscopic Pandemic Simulator (MPS). By replacing rule-based agents with rational agents whose behaviors are driven to maximize rewards, the MPS provides a better approximation of real world dynamics. To …
The recent outbreak of COVID-19 poses a serious threat to people's lives. Epidemic control strategies have also caused damage to the economy by cutting off humans' daily commute. In this paper, we develop an Individual-based Reinforcement Learning Epidemic Control Agent (IDRLECA) to search for smart epidemic control strategies that can simultaneously minimize infections and the cost of mobility intervention. IDRLECA first hires an infection probability model to calculate the current infection probability of each individual. Then, the infection probabilities together with individuals' health st…
Naloxone, an opioid antagonist, has been widely used to save lives from opioid overdose, a leading cause for death in the opioid epidemic. However, naloxone has short brain retention ability, which limits its therapeutic efficacy. Developing better opioid antagonists is critical in combating the opioid epidemic.Instead of exhaustively searching in a huge chemical space for better opioid antagonists, we adopt reinforcement learning which allows efficient gradient-based search towards molecules with desired physicochemical and/or biological properties. Specifically, we implement a deep reinforce…
This work examines the use of reinforcement learning (RL) to optimize cyclic lockdowns, which is one of the methods available for control of the COVID-19 pandemic. The problem is structured as an optimal control system for tracking a reference value, corresponding to the maximum usage level of a critical resource, such as ICU beds. However, instead of using conventional optimal control methods, RL is used to find optimal control policies. A framework was developed to calculate optimal cyclic lockdown timings using an RL-based on-off controller. The RL-based controller is implemented as an RL a…
Istituto di Analisi dei Sistemi ed Informatica “A. Ruberti”, Consiglio Nazionale delle Ricerche（意大利国家研究委员会“A.鲁贝尔蒂”系统分析与信息研究所）；University of Catania（卡塔尼亚大学）；Politecnico di Torino（都灵理工大学）
We characterize the reachability probabilities in stochastic directed graphs by means of reinforcement learning methods. In particular, we show that the dynamics of the transition probabilities in a stochastic digraph can be modeled via a difference inclusion, which, in turn, can be interpreted as a Markov decision process. Using the latter framework, we offer a methodology to design reward functions to provide upper and lower bounds on the reachability probabilities of a set of nodes for stochastic digraphs. The effectiveness of the proposed technique is demonstrated by application to the dif…
Deep reinforcement learning is actively used for training autonomous car policies in a simulated driving environment. Due to the large availability of various reinforcement learning algorithms and the lack of their systematic comparison across different driving scenarios, we are unsure of which ones are more effective for training autonomous car software in single-agent as well as multi-agent driving environments. A benchmarking framework for the comparison of deep reinforcement learning in a vision-based autonomous driving will open up the possibilities for training better autonomous car driv…
Recent developments in deep reinforcement learning are concerned with creating decision-making agents which can perform well in various complex domains. A particular approach which has received increasing attention is multi-agent reinforcement learning, in which multiple agents learn concurrently to coordinate their actions. In such multi-agent environments, additional learning problems arise due to the continually changing decision-making policies of agents. This paper surveys recent works that address the non-stationarity problem in multi-agent deep reinforcement learning. The surveyed metho…
GRASP Laboratory（GRASP实验室）；University of Pennsylvania（宾夕法尼亚大学）
In this paper, we explore using deep reinforcement learning for problems with multiple agents. Most existing methods for deep multi-agent reinforcement learning consider only a small number of agents. When the number of agents increases, the dimensionality of the input and control spaces increase as well, and these methods do not scale well. To address this, we propose casting the multi-agent reinforcement learning problem as a distributed optimization problem. Our algorithm assumes that for multi-agent settings, policies of individual agents in a given population live close to each other in p…
Learning-based approaches for solving large sequential decision making problems have become popular in recent years. The resulting agents perform differently and their characteristics depend on those of the underlying learning approach. Here, we consider a benchmark planning problem from the reinforcement learning domain, the Racetrack, to investigate the properties of agents derived from different deep (reinforcement) learning approaches. We compare the performance of deep supervised learning, in particular imitation learning, to reinforcement learning for the Racetrack model. We find that im…
Reinforcement Learning and the Evolutionary Strategy are two major approaches in addressing complicated control problems. Both are strong contenders and have their own devotee communities. Both groups have been very active in developing new advances in their own domain and devising, in recent years, leading-edge techniques to address complex continuous control tasks. Here, in the context of Deep Reinforcement Learning, we formulate a parallelized version of the Proximal Policy Optimization method and a Deep Deterministic Policy Gradient method. Moreover, we conduct a thorough comparison betwee…
In deep reinforcement learning, building policies of high-quality is challenging when the feature space of states is small and the training data is limited. Despite the success of previous transfer learning approaches in deep reinforcement learning, directly transferring data or models from an agent to another agent is often not allowed due to the privacy of data and/or models in many privacy-aware applications. In this paper, we propose a novel deep reinforcement learning framework to federatively build models of high-quality for agents with consideration of their privacies, namely Federated …
DeepMind（深度思维）；Imperial College London（伦敦帝国理工学院）；Santa Fe Institute（圣塔菲研究所）
We characterise the problem of abstraction in the context of deep reinforcement learning. Various well established approaches to analogical reasoning and associative memory might be brought to bear on this issue, but they present difficulties because of the need for end-to-end differentiability. We review developments in AI and machine learning that could facilitate their adoption.
University of Electronic Science and Technology of China（电子科技大学）
With the rapid development of deep learning, deep reinforcement learning (DRL) began to appear in the field of resource scheduling in recent years. Based on the previous research on DRL in the literature, we introduce online resource scheduling algorithm DeepRM2 and the offline resource scheduling algorithm DeepRM_Off. Compared with the state-of-the-art DRL algorithm DeepRM and heuristic algorithms, our proposed algorithms have faster convergence speed and better scheduling efficiency with regarding to average slowdown time, job completion time and rewards.
Missouri University of Science and Technology（密苏里科技大学）
The real-time strategy game of StarCraft II has been posed as a challenge for reinforcement learning by Google's DeepMind. This study examines the use of an agent based on the Monte-Carlo Tree Search algorithm for optimizing the build order in StarCraft II, and discusses how its performance can be improved even further by combining it with a deep reinforcement learning neural network. The experimental results accomplished using Monte-Carlo Tree Search achieves a score similar to a novice human player by only using very limited time and computational resources, which paves the way to achieving …
This paper presents 'SimpleDS', a simple and publicly available dialogue system trained with deep reinforcement learning. In contrast to previous reinforcement learning dialogue systems, this system avoids manual feature engineering by performing action selection directly from raw text of the last system and (noisy) user responses. Our initial results, in the restaurant domain, show that it is indeed possible to induce reasonable dialogue behaviour with an approach that aims for high levels of automation in dialogue control for intelligent interactive agents.
Max Planck Institute for Intelligent Systems（马克斯·普朗克智能系统研究所）；ETH Zürich（苏黎世联邦理工学院）；Imperial College（帝国理工学院）
Simulating the spread of infectious diseases in human communities is critical for predicting the trajectory of an epidemic and verifying various policies to control the devastating impacts of the outbreak. Many existing simulators are based on compartment models that divide people into a few subsets and simulate the dynamics among those subsets using hypothesized differential equations. However, these models lack the requisite granularity to study the effect of intelligent policies that influence every individual in a particular way. In this work, we introduce a simulator software capable of m…
Recent advances in Reinforcement Learning, grounded on combining classical theoretical results with Deep Learning paradigm, led to breakthroughs in many artificial intelligence tasks and gave birth to Deep Reinforcement Learning (DRL) as a field of research. In this work latest DRL algorithms are reviewed with a focus on their theoretical justification, practical limitations and observed empirical properties.
Carnegie Mellon University（卡内基梅隆大学）；California Institute of Technology（加州理工学院）；Harvard University（哈佛大学）
We study reinforcement learning (RL) in a setting with a network of agents whose states and actions interact in a local manner where the objective is to find localized policies such that the (discounted) global reward is maximized. A fundamental challenge in this setting is that the state-action space size scales exponentially in the number of agents, rendering the problem intractable for large networks. In this paper, we propose a Scalable Actor Critic (SAC) framework that exploits the network structure and finds a localized policy that is an $O(ρ^κ)$-approximation of a stationary point of th…
We present a new deep meta reinforcement learner, which we call Deep Episodic Value Iteration (DEVI). DEVI uses a deep neural network to learn a similarity metric for a non-parametric model-based reinforcement learning algorithm. Our model is trained end-to-end via back-propagation. Despite being trained using the model-free Q-learning objective, we show that DEVI's model-based internal structure provides `one-shot' transfer to changes in reward and transition structure, even for tasks with very high-dimensional state spaces.
Aiming at a comprehensive and concise tutorial survey, recap of variational inference and reinforcement learning with Probabilistic Graphical Models are given with detailed derivations. Reviews and comparisons on recent advances in deep reinforcement learning are made from various aspects. We offer detailed derivations to a taxonomy of Probabilistic Graphical Model and Variational Inference methods in deep reinforcement learning, which serves as a complementary material on top of the original contributions.
Deep reinforcement learning is the combination of reinforcement learning (RL) and deep learning. This field of research has been able to solve a wide range of complex decision-making tasks that were previously out of reach for a machine. Thus, deep RL opens up many new applications in domains such as healthcare, robotics, smart grids, finance, and many more. This manuscript provides an introduction to deep reinforcement learning models, algorithms and techniques. Particular focus is on the aspects related to generalization and how deep RL can be used for practical applications. We assume the r…
National University of Ireland, Galway（爱尔兰国立大学戈尔韦分校）
In recent years, a specific machine learning method called deep learning has gained huge attraction, as it has obtained astonishing results in broad applications such as pattern recognition, speech recognition, computer vision, and natural language processing. Recent research has also been shown that deep learning techniques can be combined with reinforcement learning methods to learn useful representations for the problems with high dimensional raw data input. This chapter reviews the recent advances in deep reinforcement learning with a focus on the most used deep architectures such as autoe…
We propose DeepSim, a reinforcement learning environment build toolkit for ROS and Gazebo. It allows machine learning or reinforcement learning researchers to access the robotics domain and create complex and challenging custom tasks in ROS and Gazebo simulation environments. This toolkit provides building blocks of advanced features such as collision detection, behaviour control, domain randomization, spawner, and many more. DeepSim is designed to reduce the boundary between robotics and machine learning communities by providing Python interface. In this paper, we discuss the components and d…
Deep reinforcement learning is revolutionizing the artificial intelligence field. Currently, it serves as a good starting point for constructing intelligent autonomous systems which offer a better knowledge of the visual world. It is possible to scale deep reinforcement learning with the use of deep learning and do amazing tasks such as use of pixels in playing video games. In this paper, key concepts of deep reinforcement learning including reward function, differences between reinforcement learning and supervised learning and models for implementation of reinforcement are discussed. Key chal…
University of Washington（华盛顿大学）；Microsoft Research（微软研究院）
This paper introduces a novel architecture for reinforcement learning with deep neural networks designed to handle state and action spaces characterized by natural language, as found in text-based games. Termed a deep reinforcement relevance network (DRRN), the architecture represents action and state spaces with separate embedding vectors, which are combined with an interaction function to approximate the Q-function in reinforcement learning. We evaluate the DRRN on two popular text games, showing superior performance over other deep Q-learning architectures. Experiments with paraphrased acti…
The use of deep neural networks as function approximators has led to striking progress for reinforcement learning algorithms and applications. Yet the knowledge we have on decision boundary geometry and the loss landscape of neural policies is still quite limited. In this paper we propose a framework to investigate the decision boundary and loss landscape similarities across states and across MDPs. We conduct experiments in various games from Arcade Learning Environment, and discover that high sensitivity directions for neural policies are correlated across MDPs. We argue that these high sensi…
Reinforcement Learning has applications in field of mechatronics, robotics, and other resource-constrained control system. Problem of resource allocation is primarily solved using traditional predefined techniques and modern deep learning methods. The drawback of predefined and most deep learning methods for resource allocation is failing to meet the requirements in cases of uncertain system environment. We can approach problem of resource allocation in uncertain system environment alongside following certain criteria using deep reinforcement learning. Also, reinforcement learning has ability …
Aristotle University of Thessaloniki（塞萨洛尼基亚里士多德大学）
Recent developments in deep reinforcement learning have enabled the creation of agents for solving a large variety of games given a visual input. These methods have been proven successful for 2D games, like the Atari games, or for simple tasks, like navigating in mazes. It is still an open question, how to address more complex environments, in which the reward is sparse and the state space is huge. In this paper we propose a divide and conquer deep reinforcement learning solution and we test our agent in the first person shooter (FPS) game of Doom. Our work is based on previous works in deep r…
Intel Labs（英特尔研究院）；University of California, Berkeley（加州大学伯克利分校）
Many real-world systems problems require reasoning about the long term consequences of actions taken to configure and manage the system. These problems with delayed and often sequentially aggregated reward, are often inherently reinforcement learning problems and present the opportunity to leverage the recent substantial advances in deep reinforcement learning. However, in some cases, it is not clear why deep reinforcement learning is a good fit for the problem. Sometimes, it does not perform better than the state-of-the-art solutions. And in other cases, random search or greedy algorithms cou…
Deep reinforcement learning has been shown to be a powerful framework for learning policies from complex high-dimensional sensory inputs to actions in complex tasks, such as the Atari domain. In this paper, we explore output representation modeling in the form of temporal abstraction to improve convergence and reliability of deep reinforcement learning approaches. We concentrate on macro-actions, and evaluate these on different Atari 2600 games, where we show that they yield significant improvements in learning speed. Additionally, we show that they can even achieve better scores than DQN. We …
Deep reinforcement learning is poised to revolutionise the field of AI and represents a step towards building autonomous systems with a higher level understanding of the visual world. Currently, deep learning is enabling reinforcement learning to scale to problems that were previously intractable, such as learning to play video games directly from pixels. Deep reinforcement learning algorithms are also applied to robotics, allowing control policies for robots to be learned directly from camera inputs in the real world. In this survey, we begin with an introduction to the general field of reinf…
New York University（纽约大学）；University of Strathclyde（思克莱德大学）；University of Hertfordshire（赫特福德大学）；Maastricht University（马斯特里赫特大学）
Deep reinforcement learning has learned to play many games well, but failed on others. To better characterize the modes and reasons of failure of deep reinforcement learners, we test the widely used Asynchronous Actor-Critic (A2C) algorithm on four deceptive games, which are specially designed to provide challenges to game-playing agents. These games are implemented in the General Video Game AI framework, which allows us to compare the behavior of reinforcement learning-based agents with planning agents based on tree search. We find that several of these games reliably deceive deep reinforceme…
University of Cambridge（剑桥大学）；rlcore；Helmut Schmidt University（赫尔穆特·施密特大学）
Reinforcement learning (RL) tasks are challenging to implement, execute and test due to algorithmic instability, hyper-parameter sensitivity, and heterogeneous distributed communication patterns. We argue for the separation of logical component composition, backend graph definition, and distributed execution. To this end, we introduce RLgraph, a library for designing and executing reinforcement learning tasks in both static graph and define-by-run paradigms. The resulting implementations are robust, incrementally testable, and yield high performance across different deep learning frameworks an…
Universidad Central de Chile（智利中央大学）；Deakin University（迪肯大学）；Universidade de Pernambuco（伯南布哥大学）
Robots are extending their presence in domestic environments every day, being more common to see them carrying out tasks in home scenarios. In the future, robots are expected to increasingly perform more complex tasks and, therefore, be able to acquire experience from different sources as quickly as possible. A plausible approach to address this issue is interactive feedback, where a trainer advises a learner on which actions should be taken from specific states to speed up the learning process. Moreover, deep reinforcement learning has been recently widely utilized in robotics to learn the en…
National University of Singapore（新加坡国立大学）；National University Hospital（国立大学医院）
Owe to the recent advancements in Artificial Intelligence especially deep learning, many data-driven decision support systems have been implemented to facilitate medical doctors in delivering personalized care. We focus on the deep reinforcement learning (DRL) models in this paper. DRL models have demonstrated human-level or even superior performance in the tasks of computer vision and game playings, such as Go and Atari game. However, the adoption of deep reinforcement learning techniques in clinical decision optimization is still rare. We present the first survey that summarizes reinforcemen…
University of Cambridge（剑桥大学）；Google DeepMind（谷歌DeepMind）；UC Berkeley（加州大学伯克利分校）
Reinforcement learning holds the promise of enabling autonomous robots to learn large repertoires of behavioral skills with minimal human intervention. However, robotic applications of reinforcement learning often compromise the autonomy of the learning process in favor of achieving training times that are practical for real physical systems. This typically involves introducing hand-engineered policy representations and human-supplied demonstrations. Deep reinforcement learning alleviates this limitation by training general-purpose neural network policies, but applications of direct deep reinf…
