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arXiv 2003.12886q-bio.OT
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SARS-CoV-2(COVID-19)编号

SARS-CoV-2 (COVID-19) by the numbers

Yinon M. Bar-On, Avi I. Flamholz, Rob Phillips, Ron Milo

摘要:

目前的SARS-CoV-2大流行是一个严酷的提醒,无论是在单一的人类宿主中,还是在各大洲的感染浪潮中,病毒动态往往是一个关于数字的故事。在这张快照中,我们的目标是为关键数字提供一站式,精心策划的图形来源,帮助我们了解驱动当前全球危机的病毒。讨论围绕两个广泛的主题:1)病毒本身的生物学和2)单一人类宿主感染的特征。我们的一页摘要提供了与SARS-CoV-2有关的关键数字,主要基于同行评议的文献。下文附有注释的参考资料证实了以摘要格式报告的数字。我们敦促读者记住,仍然存在许多不确定性,对这一大流行病及其驱动病毒的了解正在迅速发展。在下面的段落中,我们提供了“信封背面”的计算,这些计算说明了通过了解一些关键数字和使用定量逻辑可以获得的见解。这些计算有助于通过健全性检查来改善我们的直觉,但不能取代详细的流行病学分析。

英文摘要:

The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a one-stop, curated graphical source for the key numbers that help us understand the virus driving our current global crisis. The discussion is framed around two broad themes: 1) the biology of the virus itself and 2) the characteristics of the infection of a single human host. Our one-page summary provides the key numbers pertaining to SARS-CoV-2, based mostly on peer-reviewed literature. The numbers reported in summary format are substantiated by the annotated references below. Readers are urged to remember that much uncertainty remains and knowledge of this pandemic and the virus driving it is rapidly evolving. In the paragraphs below we provide "back of the envelope" calculations that exemplify the insights that can be gained from knowing some key numbers and using quantitative logic. These calculations serve to improve our intuition through sanity checks, but do not replace detailed epidemiological analysis.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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