Nowadays the term 'sign problem' is used to identify two different problems. The ideas to overcome the first type of the 'sign problem' of strongly oscillating complex valued imtegrand in the Feynman path integrals comes from Picard-Lefschetz theory and a complex version of Morse theory. The main idea is to select Lefschetz thimbles as the cycle approaching the critical point at the path-integration, where the imaginary part of the complex action stays constant. Since the imaginary part of the action is constant on each thimble, the sign problem disappears and the integral can be calculated much more effectively. Here based on the Metropolis -- Hastings algorithm a new method of calculations of the integral of the strongly oscillating integrands has been prosed. Some simple test calculation and comparison with available analytical results have been carried out. The second type of the 'sign problem' arises at studies Fermi systems by path integral approach and is caused by the requirement of antisymmetrization of the real valued matrix elements of the density matrix. An explicit analytical expression for effective pair pseudopotential in phase space has been discussed in Wigner formulation of quantum mechanics. Obtained pseudopotential allow to account for Fermi statistical effects as realizes the Pauli blocking of fermions due to the repulsion between identical fermions, which prevents their occupation of same phase space cell. To test this approach, calculations of the momentum distribution function of the ideal system of Fermi particles have been presented over a wide range of momentum and degeneracy parameter.
In this paper, we investigate DNA denaturation through Statistical Mechanics and show that exceptional polynomials lead to DNA mutation. We consider a DNA model with two chains connected by Morse potential representing the H bonds, and then we calculate the partition function for this model. The partition function is converted into a Schrödinger like an equation. We exploit the techniques of SUSY quantum mechanics to model DNA mutation. We also compute the thermal denaturation of DNA for each mutated state.
The statistical mechanics method is developed for determination of generating function of like-sign spin clusters' size distribution in Ising model as modification of Ising-Potts model by K. K. Murata (1979). It is applied to the ferromagnetic Ising model on Bethe lattice. The analytical results for the field-temperature percolation phase diagram of + spin clusters and their size distribution are obtained. The last appears to be proportional to that of the classical non-correlated bond percolation with the bond probability, which depends on temperature and Ising model parameters.
This note presents a minimal approach to the origin of life, following standard ideas. We pay special attention to the point of view of non-equilibrium statistical mechanics, and in particular to detailed balance. As a consequence we propose a characterization of pre-biological states.
These are the lecture notes for quantum and statistical mechanics courses that are given by DC at Ben-Gurion University. They are complementary to "Lecture Notes in Quantum Mechanics" [arXiv: quant-ph/0605180]. Some additional topics are covered, including: introduction to master equations; non-equilibrium processes; fluctuation theorems; linear response theory; adiabatic transport; the Kubo formalism; and the scattering approach to mesoscopics.
