Causal theory is now widely developed with many applications to medicine and public health. However within the discipline of reliability, although causation is a key concept in this field, there has been much less theoretical attention. In this paper, we will demonstrate how some aspects of established causal methodology can be translated via trees, and more specifically chain event graphs, into domain of reliability theory to help the probability modeling of failures. We further show how various domain specific concepts of causality particular to reliability can be imported into more generic causal algebras and so demonstrate how these disciplines can inform each other. This paper is informed by a detailed analysis of maintenance records associated with a large electrical distribution company. Causal hypotheses embedded within these natural language texts are extracted and analyzed using the new graphical framework we introduced here.
Iowa State University（爱荷华州立大学）；Department of Computer Science（计算机科学系）
We use the implicitization procedure to generate polynomial equality constraints on the set of distributions induced by local interventions on variables governed by a causal Bayesian network with hidden variables. We show how we may reduce the complexity of the implicitization problem and make the problem tractable in certain causal Bayesian networks. We also show some preliminary results on the algebraic structure of polynomial constraints. The results have applications in distinguishing between causal models and in testing causal models with combined observational and experimental data.
Max-Planck Institute for Biological Cybernetics（马克斯·普朗克生物控制论研究所）
Discovering causal relationships is a hard task, often hindered by the need for intervention, and often requiring large amounts of data to resolve statistical uncertainty. However, humans quickly arrive at useful causal relationships. One possible reason is that humans extrapolate from past experience to new, unseen situations: that is, they encode beliefs over causal invariances, allowing for sound generalization from the observations they obtain from directly acting in the world. Here we outline a Bayesian model of causal induction where beliefs over competing causal hypotheses are modeled u…
Mila - Québec AI Institute（米拉-魁北克人工智能研究所）；McGill University（麦吉尔大学）；ÉTS Montréal（蒙特利尔高等技术学院）
Learning predictors that do not rely on spurious correlations involves building causal representations. However, learning such a representation is very challenging. We, therefore, formulate the problem of learning a causal representation from high dimensional data and study causal recovery with synthetic data. This work introduces a latent variable decoder model, Decoder BCD, for Bayesian causal discovery and performs experiments in mildly supervised and unsupervised settings. We present a series of synthetic experiments to characterize important factors for causal discovery and show that usin…
Cornell University（康奈尔大学）；Indian Institute of Science（印度科学学院）；MIT（麻省理工学院）
We consider testing and learning problems on causal Bayesian networks as defined by Pearl (Pearl, 2009). Given a causal Bayesian network $\mathcal{M}$ on a graph with $n$ discrete variables and bounded in-degree and bounded `confounded components', we show that $O(\log n)$ interventions on an unknown causal Bayesian network $\mathcal{X}$ on the same graph, and $\tilde{O}(n/ε^2)$ samples per intervention, suffice to efficiently distinguish whether $\mathcal{X}=\mathcal{M}$ or whether there exists some intervention under which $\mathcal{X}$ and $\mathcal{M}$ are farther than $ε$ in total variati…
Continuous time Bayesian networks are investigated with a special focus on their ability to express causality. A framework is presented for doing inference in these networks. The central contributions are a representation of the intensity matrices for the networks and the introduction of a causality measure. A new model for high-frequency financial data is presented. It is calibrated to market data and by the new causality measure it performs better than older models.
TU Graz（格拉茨技术大学）；ETH Zürich（苏黎世联邦理工学院）；MPI for Intelligent Systems（马克斯·普朗克智能系统研究所）；University of Cambridge（剑桥大学）
Causal discovery and causal reasoning are classically treated as separate and consecutive tasks: one first infers the causal graph, and then uses it to estimate causal effects of interventions. However, such a two-stage approach is uneconomical, especially in terms of actively collected interventional data, since the causal query of interest may not require a fully-specified causal model. From a Bayesian perspective, it is also unnatural, since a causal query (e.g., the causal graph or some causal effect) can be viewed as a latent quantity subject to posterior inference -- other unobserved qua…
Bayesian probability theory is one of the most successful frameworks to model reasoning under uncertainty. Its defining property is the interpretation of probabilities as degrees of belief in propositions about the state of the world relative to an inquiring subject. This essay examines the notion of subjectivity by drawing parallels between Lacanian theory and Bayesian probability theory, and concludes that the latter must be enriched with causal interventions to model agency. The central contribution of this work is an abstract model of the subject that accommodates causal interventions in a…
How should we intervene on an unknown structural equation model to maximize a downstream variable of interest? This setting, also known as causal Bayesian optimization (CBO), has important applications in medicine, ecology, and manufacturing. Standard Bayesian optimization algorithms fail to effectively leverage the underlying causal structure. Existing CBO approaches assume noiseless measurements and do not come with guarantees. We propose the model-based causal Bayesian optimization algorithm (MCBO) that learns a full system model instead of only modeling intervention-reward pairs. MCBO prop…
We offer a graphical interpretation of unfairness in a dataset as the presence of an unfair causal path in the causal Bayesian network representing the data-generation mechanism. We use this viewpoint to revisit the recent debate surrounding the COMPAS pretrial risk assessment tool and, more generally, to point out that fairness evaluation on a model requires careful considerations on the patterns of unfairness underlying the training data. We show that causal Bayesian networks provide us with a powerful tool to measure unfairness in a dataset and to design fair models in complex unfairness sc…
The goal of causal inference is to understand the outcome of alternative courses of action. However, all causal inference requires assumptions. Such assumptions can be more influential than in typical tasks for probabilistic modeling, and testing those assumptions is important to assess the validity of causal inference. We develop model criticism for Bayesian causal inference, building on the idea of posterior predictive checks to assess model fit. Our approach involves decomposing the problem, separately criticizing the model of treatment assignments and the model of outcomes. Conditioned on …
Multivariate functional data arise in a wide range of applications. One fundamental task is to understand the causal relationships among these functional objects of interest, which has not yet been fully explored. In this article, we develop a novel Bayesian network model for multivariate functional data where the conditional independence and causal structure are both encoded by a directed acyclic graph. Specifically, we allow the functional objects to deviate from Gaussian process, which is adopted by most existing functional data analysis models. The more reasonable non-Gaussian assumption i…
We extend the empirical results from the structural equation model (SEM) published in the paper Assortment Planning for Retail Buying, Retail Store Operations, and Firm Performance [1] by implementing the directed acyclic graph as a causal Bayesian neural network. Neural network convergence is shown to improve with the removal of the node with the weakest SEM path when variational inference is provided by perturbing weights with Flipout layers, while results from perturbing weights at the output with the Vadam optimizer are inconclusive.
A major problem for the learning of Bayesian networks (BNs) is the exponential number of parameters needed for conditional probability tables. Recent research reduces this complexity by modeling local structure in the probability tables. We examine the use of log-linear local models. While log-linear models in this context are not new (Whittaker, 1990; Buntine, 1991; Neal, 1992; Heckerman and Meek, 1997), for structure learning they are generally subsumed under a naive Bayes model. We describe an alternative interpretation, and use a Minimum Message Length (MML) (Wallace, 1987) metric for stru…
Stanford University（斯坦福大学）；Facebook AI Research（Facebook人工智能研究院）；University of California, Los Angeles（加州大学洛杉矶分校）
A structural equation model (SEM) is an effective framework to reason over causal relationships represented via a directed acyclic graph (DAG). Recent advances have enabled effective maximum-likelihood point estimation of DAGs from observational data. However, a point estimate may not accurately capture the uncertainty in inferring the underlying graph in practical scenarios, wherein the true DAG is non-identifiable and/or the observed dataset is limited. We propose Bayesian Causal Discovery Nets (BCD Nets), a variational inference framework for estimating a distribution over DAGs characterizi…
It is common practice in using regression type models for inferring causal effects, that inferring the correct causal relationship requires extra covariates are included or ``adjusted for''. Without performing this adjustment erroneous causal effects can be inferred. Given this phenomenon it is common practice to include as many covariates as possible, however such advice comes unstuck in the presence of M-bias. M-Bias is a problem in causal inference where the correct estimation of treatment effects requires that certain variables are not adjusted for i.e. are simply neglected from inclusion …
University of Warwick（华威大学）；The Alan Turing Institute（艾伦·图灵研究所）；Amazon（亚马逊）
This paper studies the problem of globally optimizing a variable of interest that is part of a causal model in which a sequence of interventions can be performed. This problem arises in biology, operational research, communications and, more generally, in all fields where the goal is to optimize an output metric of a system of interconnected nodes. Our approach combines ideas from causal inference, uncertainty quantification and sequential decision making. In particular, it generalizes Bayesian optimization, which treats the input variables of the objective function as independent, to scenario…
Goal-Oriented Sequential Bayesian Experimental Design for Causal Learning
Department of Computer Science and Engineering（计算机科学与工程系）；Department of Mechanical Engineering（机械工程系）；Gilbert S. Omenn Department of Computational Medicine and Bioinformatics（Gilbert S. Omenn 计算医学与生物信息学部门）
University of Warwick（华威大学）；The Alan Turing Institute（阿兰·图灵研究所）；Microsoft Research Cambridge（微软剑桥研究院）
This paper studies the problem of performing a sequence of optimal interventions in a causal dynamical system where both the target variable of interest and the inputs evolve over time. This problem arises in a variety of domains e.g. system biology and operational research. Dynamic Causal Bayesian Optimization (DCBO) brings together ideas from sequential decision making, causal inference and Gaussian process (GP) emulation. DCBO is useful in scenarios where all causal effects in a graph are changing over time. At every time step DCBO identifies a local optimal intervention by integrating both…
We consider learning the possible causal direction of two observed variables in the presence of latent confounding variables. Several existing methods have been shown to consistently estimate causal direction assuming linear or some type of nonlinear relationship and no latent confounders. However, the estimation results could be distorted if either assumption is actually violated. In this paper, we first propose a new linear non-Gaussian acyclic structural equation model with individual-specific effects that allows latent confounders to be considered. We then propose an empirical Bayesian app…
School of Mathematical and Data Science（数学与数据科学学院）；West Virginia University（西弗吉尼亚大学）；Department of Chemical and Biomedical Engineering（化学与生物医学工程系）；The Medical College of Wisconsin（威斯康星医学院）；Department of Biostatistics and Bioinformatics（生物统计学与生物信息学系）
Università Cattolica del Sacro Cuore（天主教圣心大学）；Università degli Studi di Milano-Bicocca（米兰比可卡大学）
Directed Acyclic Graphs (DAGs) provide a powerful framework to model causal relationships among variables in multivariate settings; in addition, through the do-calculus theory, they allow for the identification and estimation of causal effects between variables also from pure observational data. In this setting, the process of inferring the DAG structure from the data is referred to as causal structure learning or causal discovery. We introduce BCDAG, an R package for Bayesian causal discovery and causal effect estimation from Gaussian observational data, implementing the Markov chain Monte Ca…
Our approach to Mendelian Randomization (MR) analysis is designed to increase reproducibility of causal effect "discoveries" by: (i) using a Bayesian approach to inference; (ii) replacing the point null hypothesis with a region of practical equivalence consisting of values of negligible magnitude for the effect of interest, while exploiting the ability of Bayesian analysis to quantify the evidence of the effect falling inside/outside the region; (iii) rejecting the usual binary decision logic in favour of a ternary logic where the hypothesis test may result in either an acceptance or a rejecti…
COBRA-PPM: A Causal Bayesian Reasoning Architecture Using Probabilistic Programming for Robot Manipulation Under Uncertainty
Oxford Robotics Institute, Dept. Engineering Science, University of Oxford, UK（牛津大学机器人研究所）；Microsoft Research, Redmond, WA, USA（微软研究院）；Bristol Robotics Laboratory, School of Engineering, University of the West of England, Bristol, UK（布里斯托尔机器人实验室）
University of Sussex（萨塞克斯大学）；Surgo Foundation（苏尔戈基金会）；Harvard T.H. Chan School of Public Health（哈佛大学陈曾熙公共卫生学院）；University of Washington（华盛顿大学）
In solving real-world problems like changing healthcare-seeking behaviors, designing interventions to improve downstream outcomes requires an understanding of the causal links within the system. Causal Bayesian Networks (BN) have been proposed as one such powerful method. In real-world applications, however, confidence in the results of BNs are often moderate at best. This is due in part to the inability to validate against some ground truth, as the DAG is not available. This is especially problematic if the learned DAG conflicts with pre-existing domain doctrine. At the policy level, one must…
Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex multi-level systems. We go one step further and advocate for the consideration of causal representations of the interactions in living systems.We present the causal formalism and bring it out in the context of biological networks, when the data is observational. We also discuss its ability to decipher the causal information flow as observed in gene expression.…
The use of genetic variants as instrumental variables - an approach known as Mendelian randomization - is a popular epidemiological method for estimating the causal effect of an exposure (phenotype, biomarker, risk factor) on a disease or health-related outcome from observational data. Instrumental variables must satisfy strong, often untestable assumptions, which means that finding good genetic instruments among a large list of potential candidates is challenging. This difficulty is compounded by the fact that many genetic variants influence more than one phenotype through different causal pa…
Motivated by environmental policy questions, we address the challenges of estimation, change point detection, and uncertainty quantification of a causal exposure-response function (CERF). Under a potential outcome framework, the CERF describes the relationship between a continuously varying exposure (or treatment) and its causal effect on an outcome. We propose a new Bayesian approach that relies on a Gaussian process (GP) model to estimate the CERF nonparametrically. To achieve the desired separation of design and analysis phases, we parametrize the covariance (kernel) function of the GP to m…
Analysts often use data-driven approaches to supplement their substantive knowledge when selecting covariates for causal effect estimation. Multiple variable selection procedures tailored for causal effect estimation have been devised in recent years, but additional developments are still required to adequately address the needs of data analysts. In this paper, we propose a Generalized Bayesian Causal Effect Estimation (GBCEE) algorithm to perform variable selection and produce double robust estimates of causal effects for binary or continuous exposures and outcomes. GBCEE employs a prior dist…
Discrete Causal Representations from Heterogeneous Domains: A Bayesian Approach with Social Survey Applications
Department of Statistics, University of Chicago（芝加哥大学统计学系）；University of Tübingen（图宾根大学）；Department of Statistics & Data Science Institute, University of Chicago（芝加哥大学统计学与数据科学研究所）；Seminars for Statistics, ETH Zürich（苏黎世联邦理工学院统计系）
Helsinki Institute for Information Technology（赫尔辛基信息技术研究所）；University of Helsinki（赫尔辛基大学）
Methods for automated discovery of causal relationships from non-interventional data have received much attention recently. A widely used and well understood model family is given by linear acyclic causal models (recursive structural equation models). For Gaussian data both constraint-based methods (Spirtes et al., 1993; Pearl, 2000) (which output a single equivalence class) and Bayesian score-based methods (Geiger and Heckerman, 1994) (which assign relative scores to the equivalence classes) are available. On the contrary, all current methods able to utilize non-Gaussianity in the data (Shimi…
Gaussian process (GP) covariance function is proposed as a matching tool in GPMatch within a full Bayesian framework under relatively weaker causal assumptions. The matching is accomplished by utilizing GP prior covariance function to define matching distance. We show that GPMatch provides a doubly robust estimate of the averaged treatment effect (ATE) much like the G-estimation, the ATE is correctly estimated when either conditions are satisfied: 1) the GP mean function correctly specifies potential outcome \(Y^{(0)}\); or 2) the GP covariance function correctly specifies matching structure. …
Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput genetic data. A typical approach consists of a series of conditional independence tests on the covariance structure meant to progressively reduce the space of possible causal models. We propose a novel efficient Bayesian method for discovering the local causal relationships among triplets of (normally distributed) variables. In our approach, we score the patter…
