This paper presents a robust deep learning framework developed to detect respiratory diseases from recordings of respiratory sounds. The complete detection process firstly involves front end feature extraction where recordings are transformed into spectrograms that convey both spectral and temporal information. Then a back-end deep learning model classifies the features into classes of respiratory disease or anomaly. Experiments, conducted over the ICBHI benchmark dataset of respiratory sounds, evaluate the ability of the framework to classify sounds. Two main contributions are made in this paper. Firstly, we provide an extensive analysis of how factors such as respiratory cycle length, time resolution, and network architecture, affect final prediction accuracy. Secondly, a novel deep learning based framework is proposed for detection of respiratory diseases and shown to perform extremely well compared to state of the art methods.
Austria Institute of Technology（奥地利技术研究所）；Queen Mary University of London（伦敦玛丽女王大学）；University of Lübeck（吕贝克大学）；Singapore Institute of Technology（新加坡理工学院）
This paper presents an inception-based deep neural network for detecting lung diseases using respiratory sound input. Recordings of respiratory sound collected from patients are firstly transformed into spectrograms where both spectral and temporal information are well presented, referred to as front-end feature extraction. These spectrograms are then fed into the proposed network, referred to as back-end classification, for detecting whether patients suffer from lung-relevant diseases. Our experiments, conducted over the ICBHI benchmark meta-dataset of respiratory sound, achieve competitive I…
Respiratory diseases are among the most common causes of severe illness and death worldwide. Prevention and early diagnosis are essential to limit or even reverse the trend that characterizes the diffusion of such diseases. In this regard, the development of advanced computational tools for the analysis of respiratory auscultation sounds can become a game changer for detecting disease-related anomalies, or diseases themselves. In this work, we propose a novel learning framework for respiratory auscultation sound data. Our approach combines state-of-the-art feature extraction techniques and adv…
University of Kent（肯特大学）；Queen Mary University of London（伦敦玛丽女王大学）；University of Lübeck（吕贝克大学）；Singapore Institute of Technology（新加坡理工学院）
This paper presents and explores a robust deep learning framework for auscultation analysis. This aims to classify anomalies in respiratory cycles and detect disease, from respiratory sound recordings. The framework begins with front-end feature extraction that transforms input sound into a spectrogram representation. Then, a back-end deep learning network is used to classify the spectrogram features into categories of respiratory anomaly cycles or diseases. Experiments, conducted over the ICBHI benchmark dataset of respiratory sounds, confirm three main contributions towards respiratory-sound…
Center for Digital Safety & Security, Austria Institute of Technology（奥地利技术研究所数字安全与安保中心）；School of Computer Science and Electronic Engineering, University of Essex（埃塞克斯大学计算机科学与电子工程学院）；FPT Software Company Limited（FPT软件有限公司）；Singapore Institute of Technology（新加坡理工学院）
In this paper, we evaluate various deep learning frameworks for detecting respiratory anomalies from input audio recordings. To this end, we firstly transform audio respiratory cycles collected from patients into spectrograms where both temporal and spectral features are presented, referred to as the front-end feature extraction. We then feed the spectrograms into back-end deep learning networks for classifying these respiratory cycles into certain categories. Finally, results from high-performed deep learning frameworks are fused to obtain the best score. Our experiments on ICBHI benchmark da…
A Deep Learning Architecture with Spatio-Temporal Focusing for Detecting Respiratory Anomalies
School of Electronic Engineering and Computer Science, Queen Mary University of London（伦敦玛丽女王大学电子工程与计算机科学学院）；School of Computer Science and Electronic Engineering, University of Essex（埃塞克斯大学计算机科学与电子工程学院）；Center for Digital Safety & Security, Austrian Institute of Technology（奥地利技术研究所数字安全与安保中心）；Amazon Alexa（亚马逊Alexa）；Nuffield Department of Clinical Neurosciences, University of Oxford（牛津大学纳菲尔德临床神经科学系）
The issue in respiratory sound classification has attained good attention from the clinical scientists and medical researcher's group in the last year to diagnosing COVID-19 disease. To date, various models of Artificial Intelligence (AI) entered into the real-world to detect the COVID-19 disease from human-generated sounds such as voice/speech, cough, and breath. The Convolutional Neural Network (CNN) model is implemented for solving a lot of real-world problems on machines based on Artificial Intelligence (AI). In this context, one dimension (1D) CNN is suggested and implemented to diagnose …
An Inception-Residual-Based Architecture with Multi-Objective Loss for Detecting Respiratory Anomalies
Queen Mary University of London（伦敦玛丽女王大学）；University of Essex（埃塞克斯大学）；Austrian Institute of Technology（奥地利技术研究所）；Amazon Alexa（亚马逊Alexa）；University of Oxford（牛津大学）
XAI-Driven Spectral Analysis of Cough Sounds for Respiratory Disease Characterization
Universidad de Valladolid（巴利亚多利德大学）；Instituto de Neurociencias de Castilla y León (INCYL)（卡斯蒂利亚-莱昂神经科学研究所（INCYL））；Complejo Asistencial Universitario de Salamanca（萨拉曼卡大学医疗综合体）
The World Health Organization (WHO) has announced a COVID-19 was a global pandemic in March 2020. It was initially started in china in the year 2019 December and affected an expanding number of nations in various countries in the last few months. In this particular situation, many techniques, methods, and AI-based classification algorithms are put in the spotlight in reacting to fight against it and reduce the rate of such a global health crisis. COVID-19's main signs are heavy temperature, different cough, cold, breathing shortness, and a combination of loss of sense of smell and chest tightn…
Towards reliable respiratory disease diagnosis based on cough sounds and vision transformers
Luca Healthcare（卢卡医疗）；Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院附属瑞金医院）；Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Disease（上海市呼吸道传染病应急防控诊治重点实验室）
In this study, a machine learning model was developed for automatically detecting respiratory system sounds such as sneezing and coughing in disease diagnosis. The automatic model and approach development of breath sounds, which carry valuable information, results in early diagnosis and treatment. A successful machine learning model was developed in this study, which was a strong response to the challenge called the "Pfizer digital medicine challenge" on the "OSFHOME" open access platform. "Environmental sound classification" called ESC-50 and AudioSet sound files were used to prepare the data…
Optimising MFCC parameters for the automatic detection of respiratory diseases
Institute of Data Science, Maastricht University（数据科学研究所，马斯特里赫特大学）；Department of Respiratory Medicine, NUTRIM Research Institute of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University（呼吸科系，营养与代谢转化研究 institute，健康医学与生命科学学院，马斯特里赫特大学）；Department of Respiratory Medicine, Maastricht University Medical Centre（呼吸科系，马斯特里赫特大学医学中心）；Department of Research and Development, Ciro（研发部，Ciro）
Tri-MTL: A Triple Multitask Learning Approach for Respiratory Disease Diagnosis
Department of Psychiatry, Wonkwang University Hospital（精神医学科，Wonkwang大学医院）；RSC LAB, MODULABS（RSC实验室，MODULABS）；The State University of New York, Korea, Republic of Korea（纽约州立大学，韩国）；Department of Pediatrics, Seoul National University Bundang Hospital（儿科，首尔国立大学医院 Bundang 分院）；Department of Pediatrics, Seoul National University College of Medicine（儿科，首尔国立大学医学院）
Developing a reliable sound detection and recognition system offers many benefits and has many useful applications in different industries. This paper examines the difficulties that exist when attempting to perform sound classification as it relates to respiratory disease classification. Some methods which have been employed such as independent component analysis and blind source separation are examined. Finally, an examination on the use of deep learning and long short-term memory networks is performed in order to identify how such a task can be implemented.
UAEU（阿拉伯联合酋长国大学）；Staffordshire University（斯塔福德郡大学）；Tianjin University of Technology（天津理工大学）
Respiratory symptoms can be a caused by different underlying conditions, and are often caused by viral infections, such as Influenza-like illnesses or other emerging viruses like the Coronavirus. These respiratory viruses, often, have common symptoms, including coughing, high temperature, congested nose, and difficulty breathing. However, early diagnosis of the type of the virus, can be crucial, especially in cases such as the recent COVID-19 pandemic. One of the factors that contributed to the spread of the pandemic, was the late diagnosis or confusing it with regular flu-like symptoms. Scien…
Patch-Mix Contrastive Learning with Audio Spectrogram Transformer on Respiratory Sound Classification
KAIST AI（韩国科学技术院人工智能学院）；Department of AI, Kyungpook National University（庆北国立大学人工智能系）；SmartSound（SmartSound公司）；Dongguk University（东国大学）；MODULABS（MODULABS机构）
Respiratory infections and chronic respiratory diseases impose a heavy health burden worldwide. Coughing is one of the most common symptoms of many such infections, and can be indicative of flare-ups of chronic respiratory diseases. Whether at a clinical or public health level, the capacity to identify bouts of coughing can aid understanding of population and individual health status. Developing health monitoring models in the context of respiratory diseases and also seasonal diseases with symptoms such as cough has the potential to improve quality of life, help clinicians and public health au…
A Cross-Lingual Acoustic Disease-Alignment Framework for Respiratory Health Assessment from Spontaneous Speech
University of Maryland, College Park（马里兰大学学院公园分校）；Sylhet MAG Osmani Medical College Hospital（锡尔赫特MAG奥斯马尼医学院医院）；Dr. M R Khan Shishu Hospital & Institute of Child Health（M R 汗儿童医院与儿童健康研究所）；Line Reflection Ltd.（Line Reflection 有限公司）
University of Cambridge（剑桥大学）；Alan Turing Institute（艾伦·图灵研究所）
Audio signals generated by the human body (e.g., sighs, breathing, heart, digestion, vibration sounds) have routinely been used by clinicians as indicators to diagnose disease or assess disease progression. Until recently, such signals were usually collected through manual auscultation at scheduled visits. Research has now started to use digital technology to gather bodily sounds (e.g., from digital stethoscopes) for cardiovascular or respiratory examination, which could then be used for automatic analysis. Some initial work shows promise in detecting diagnostic signals of COVID-19 from voice …
Imperial College London（帝国理工学院）；Griffith University（格里菲斯大学）；University of Augsburg（奥格斯堡大学）
Respiratory sound classification is an important tool for remote screening of respiratory-related diseases such as pneumonia, asthma, and COVID-19. To facilitate the interpretability of classification results, especially ones based on deep learning, many explanation methods have been proposed using prototypes. However, existing explanation techniques often assume that the data is non-biased and the prediction results can be explained by a set of prototypical examples. In this work, we develop a unified example-based explanation method for selecting both representative data (prototypes) and out…
Queen Mary University of London（伦敦玛丽女王大学）；University of Luebeck（吕贝克大学）
This thesis focuses on dealing with the task of acoustic scene classification (ASC), and then applied the techniques developed for ASC to a real-life application of detecting respiratory disease. To deal with ASC challenges, this thesis addresses three main factors that directly affect the performance of an ASC system. Firstly, this thesis explores input features by making use of multiple spectrograms (log-mel, Gamma, and CQT) for low-level feature extraction to tackle the issue of insufficiently discriminative or descriptive input features. Next, a novel Encoder network architecture is introd…
Remote screening of respiratory diseases has been widely studied as a non-invasive and early instrument for diagnosis purposes, especially in the pandemic. The respiratory sound classification task has been realized with numerous deep neural network (DNN) models due to their superior performance. However, in the high-stake medical domain where decisions can have significant consequences, it is desirable to develop interpretable models; thus, providing understandable reasons for physicians and patients. To address the issue, we propose a prototype learning framework, that jointly generates exem…
Auscultation of respiratory sounds is the primary tool for screening and diagnosing lung diseases. Automated analysis, coupled with digital stethoscopes, can play a crucial role in enabling tele-screening of fatal lung diseases. Deep neural networks (DNNs) have shown a lot of promise for such problems, and are an obvious choice. However, DNNs are extremely data hungry, and the largest respiratory dataset ICBHI has only 6898 breathing cycles, which is still small for training a satisfactory DNN model. In this work, RespireNet, we propose a simple CNN-based model, along with a suite of novel tec…
University of Augsburg（奥格斯堡大学）；Imperial College（帝国理工学院）；University Hospital Augsburg（奥格斯堡大学医院）；Ludwig-Maximilians-University Munich（慕尼黑路德维希-马克西米利安大学）
Chronic obstructive pulmonary disease (COPD) causes lung inflammation and airflow blockage leading to a variety of respiratory symptoms; it is also a leading cause of death and affects millions of individuals around the world. Patients often require treatment and hospitalisation, while no cure is currently available. As COPD predominantly affects the respiratory system, speech and non-linguistic vocalisations present a major avenue for measuring the effect of treatment. In this work, we present results on a new COPD dataset of 20 patients, showing that, by employing personalisation through spe…
The primary objective of this paper is to build classification models and strategies to identify breathing sound anomalies (wheeze, crackle) for automated diagnosis of respiratory and pulmonary diseases. In this work we propose a deep CNN-RNN model that classifies respiratory sounds based on Mel-spectrograms. We also implement a patient specific model tuning strategy that first screens respiratory patients and then builds patient specific classification models using limited patient data for reliable anomaly detection. Moreover, we devise a local log quantization strategy for model weights to r…
Mitigating Stethoscope-Induced Shortcuts in Respiratory Sound Classification under Federated Domain Generalization with Causality-Inspired Interventions
University of Illinois Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；RSC LAB（RSC实验室）；Wonkwang University（Wonkwang大学）
Recognizing patterns in lung sounds is crucial to detecting and monitoring respiratory diseases. Current techniques for analyzing respiratory sounds demand domain experts and are subject to interpretation. Hence an accurate and automatic respiratory sound classification system is desired. In this work, we took a data-driven approach to classify abnormal lung sounds. We compared the performance using three different feature extraction techniques, which are short-time Fourier transformation (STFT), Mel spectrograms, and Wav2vec, as well as three different classifiers, including pre-trained ResNe…
Sound-Dr: Reliable Sound Dataset and Baseline Artificial Intelligence System for Respiratory Illnesses
AI Center, FPT Software Company Limited（FPT软件公司人工智能中心）；Reliable Machine Learning Group（可靠机器学习小组）；School of Computer Science and Information Technology, University College Cork, Ireland（University College Cork信息科学与技术学院）
Speaker-Disentangled Remote Speech Detection of Asthma and COPD Exacerbations
Institute of Data Science, Maastricht University（数据科学研究所，马斯特里赫特大学）；NUTRIM Research Institute of Nutrition and Translational Research in Metabolism, Faculty of Health Medicine and Life Sciences, Maastricht University（营养与代谢转化研究营养研究所，健康医学与生命科学学院，马斯特里赫特大学）；Maastricht University Medical Centre（马斯特里赫特大学医学中心）
CycleGuardian: A Framework for Automatic RespiratorySound classification Based on Improved Deep clustering and Contrastive Learning
School of BioMedical Engineering, Hainan University（海南大学生物医学工程学院）；School of Electronic Information and Communications, Huazhong University of Science and Technology（华中科技大学电子信息与通信学院）；School of Information and Communication, Hainan University（海南大学信息与通信学院）
East China Normal University（华东师范大学）；Shanghai Jiao Tong University（上海交通大学）
Cough is a common symptom of respiratory and lung diseases. Cough detection is important to prevent, assess and control epidemic, such as COVID-19. This paper proposes a model to detect cough events from cough audio signals. The models are trained by the dataset combined ESC-50 dataset with self-recorded cough recordings. The test dataset contains inpatient cough recordings collected from inpatients of the respiratory disease department in Ruijin Hospital. We totally build 15 cough detection models based on different feature numbers selected by Random Frog, Uninformative Variable Elimination (…
