Cardiac kinematic parameters computed from video of $\textit{in situ}$ beating heart
Lorenzo Fassina, Giacomo Rozzi, Stefano Rossi, Simone Scacchi, Maricla Galetti, Francesco Paolo Lo Muzio, Fabrizio Del Bianco, Piero Colli Franzone, Giuseppe Pe… 展开作者
Lorenzo Fassina, Giacomo Rozzi, Stefano Rossi, Simone Scacchi, Maricla Galetti, Francesco Paolo Lo Muzio, Fabrizio Del Bianco, Piero Colli Franzone, Giuseppe Petrilli, Giuseppe Faggian, Michele Miragoli
Mechanical function of the heart during open-chest cardiac surgery is exclusively monitored by echocardiographic techniques. However, little is known about local kinematics, particularly for the reperfused regions after ischemic events. We report a novel imaging modality, which extracts local and global kinematic parameters from videos of $\textit{in situ}$ beating hearts, displaying live video cardiograms of the contraction events. A custom algorithm tracked the movement of a video marker positioned $\textit{ad hoc}$ onto a selected area and analyzed, during the entire recording, the contraction trajectory, displacement, velocity, acceleration, kinetic energy and force. Moreover, global epicardial velocity and vorticity were analyzed by means of Particle Image Velocimetry tool. We validated our new technique by i) computational modeling of cardiac ischemia, ii) video recordings of ischemic/reperfused rat hearts, iii) videos of beating human hearts before and after coronary artery bypass graft, and iv) local Frank-Starling effect. In rats, we observed a decrement of kinematic parameters during acute ischemia and a significant increment in the same region after reperfusion. We detected similar behavior in operated patients. This modality adds important functional values on cardiac outcomes and supports the intervention in a contact-free and non-invasive mode. Moreover, it does not require particular operator-dependent skills.
Towards the Emulation of the Cardiac Conduction System for Pacemaker Testing
Department of Electrical and Computer Engineering, the University of Auckland（奥克兰大学电气与计算机工程系）；Auckland Bioengineering Institute, the University of Auckland（奥克兰大学生物医学研究所）
SDF4CHD: Generative Modeling of Cardiac Anatomies with Congenital Heart Defects
Stanford University（斯坦福大学）；Cardiovascular Institute（心血管研究所）；ETH Zurich and University Zurich（苏黎世联邦理工学院和苏黎世大学）；Institute for Biomedical Engineering（生物医学工程研究所）
Integrating anatomy and electrophysiology in the healthy human heart: Insights from biventricular statistical shape analysis using universal coordinates
From Raw Segmentations to Simulation-Ready Cardiac Meshes: An Automated Framework for Anatomical Reconstruction and Virtual Cohort Generation
Gran Sasso Science Institute (GSSI)（大萨索科学研究所）；European Hospital（欧洲医院）；University of Edinburgh（爱丁堡大学）；Physics of Fluids Group, University of Twente（特温特大学流体物理小组）；INFN–Laboratori Nazionali del Gran Sasso（意大利国家核物理研究所大萨索国家实验室）
