呼吸性窦性心律失常对心输出量影响的数学和临床前研究
Mathematical and Preclinical Investigation of Respiratory Sinus Arrhythmia Effects on Cardiac Output
摘要：
呼吸性窦性心律不齐（RSA）是一种心率〈动〉<动>与呼吸同步的变异性疾病，其功能意义尚不明确。窦性心律失常的消失可能表明潜在的心力衰竭或疾病;因此，了解其如何工作和影响心肺系统将具有很大的优势，特别是通过提供数学模型。为此，基于与RSA相关的左心室弹性，利用Windkessel模型和心血管偏微分方程来获得心输出量。通过求解相应的方程，有可能提出一个新的模型来预测RSA对心输出量的影响。
英文摘要：
Respiratory sinus arrhythmia (RSA) is heart rate variability in synchrony with respiration although its functional significance not clear. The loss of sinus arrhythmia may indicate underlying heart failure or disease; therefore, there would be a great advantage of knowing how it works and affects the cardio-respiratory system, especially by providing a mathematical model. To this end, Windkessel model and cardiovascular partial differential equations are used to obtain cardiac output based on the elasticity of left ventricle, which is related to RSA. By solving the corresponding equations, it would be possible to propose a new model to predict the RSA effects on cardiac output.
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