人类多能干细胞数学模型的最新进展
The recent advances in the mathematical modelling of human pluripotent stem cells
摘要:
人类多能干细胞为再生医学和药物设计的发展带来了巨大的希望。干细胞及其特性的数学建模对于理解和量化关键行为以及开发非侵入性预后建模工具以帮助优化实验室实验是必要的。在这里,讨论了hPSC的数学建模的最新进展,包括细胞运动学,细胞增殖和集落形成,以及多能性和分化。
英文摘要:
Human pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。