ADN: Artifact Disentanglement Network for Unsupervised Metal Artifact Reduction
University of Rochester（罗切斯特大学）；University of Maryland, College Park（马里兰大学帕克分校）；Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；Peng Cheng Laboratory（鹏城实验室）
Haofu Liao, Wei-An Lin, S. Kevin Zhou, Jiebo Luo
备注：
This is the extended version of arXiv:1906.01806. This paper is accepted to IEEE Transactions on Medical Imaging
Current deep neural network based approaches to computed tomography (CT) metal artifact reduction (MAR) are supervised methods that rely on synthesized metal artifacts for training. However, as synthesized data may not accurately simulate the underlying physical mechanisms of CT imaging, the supervised methods often generalize poorly to clinical applications. To address this problem, we propose, to the best of our knowledge, the first unsupervised learning approach to MAR. Specifically, we introduce a novel artifact disentanglement network that disentangles the metal artifacts from CT images in the latent space. It supports different forms of generations (artifact reduction, artifact transfer, and self-reconstruction, etc.) with specialized loss functions to obviate the need for supervision with synthesized data. Extensive experiments show that when applied to a synthesized dataset, our method addresses metal artifacts significantly better than the existing unsupervised models designed for natural image-to-image translation problems, and achieves comparable performance to existing supervised models for MAR. When applied to clinical datasets, our method demonstrates better generalization ability over the supervised models. The source code of this paper is publicly available at https://github.com/liaohaofu/adn.
University of Rochester（罗切斯特大学）；University of Maryland, College Park（马里兰大学帕克分校）；Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）
Current deep neural network based approaches to computed tomography (CT) metal artifact reduction (MAR) are supervised methods which rely heavily on synthesized data for training. However, as synthesized data may not perfectly simulate the underlying physical mechanisms of CT imaging, the supervised methods often generalize poorly to clinical applications. To address this problem, we propose, to the best of our knowledge, the first unsupervised learning approach to MAR. Specifically, we introduce a novel artifact disentanglement network that enables different forms of generations and regulariz…
The Pennsylvania State University（宾夕法尼亚州立大学）；Johns Hopkins University（约翰斯·霍普金斯大学）；Houston Methodist Hospital（休斯顿卫理公会医院）
Accurate infarct segmentation in non-contrast CT (NCCT) images is a crucial step toward computer-aided acute ischemic stroke (AIS) assessment. In clinical practice, bilateral symmetric comparison of brain hemispheres is usually used to locate pathological abnormalities. Recent research has explored asymmetries to assist with AIS segmentation. However, most previous symmetry-based work mixed different types of asymmetries when evaluating their contribution to AIS. In this paper, we propose a novel Asymmetry Disentanglement Network (ADN) to automatically separate pathological asymmetries and int…
Deep neural network based methods have achieved promising results for CT metal artifact reduction (MAR), most of which use many synthesized paired images for training. As synthesized metal artifacts in CT images may not accurately reflect the clinical counterparts, an artifact disentanglement network (ADN) was proposed with unpaired clinical images directly, producing promising results on clinical datasets. However, without sufficient supervision, it is difficult for ADN to recover structural details of artifact-affected CT images based on adversarial losses only. To overcome these problems, h…
Z 2 Sky Technologies Inc.（Z 2 天工科技公司）；University of Rochester（罗切斯特大学）；Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS（中国科学院计算技术研究所 中国科学院智能信息处理重点实验室）；University of Science and Technology of China（中国科学技术大学）；Suzhou Institute for Advance Research, University of Science and Technology of China（中国科学技术大学苏州高等研究院）
Spinal surgery planning necessitates automatic segmentation of vertebrae in cone-beam computed tomography (CBCT), an intraoperative imaging modality that is widely used in intervention. However, CBCT images are of low-quality and artifact-laden due to noise, poor tissue contrast, and the presence of metallic objects, causing vertebra segmentation, even manually, a demanding task. In contrast, there exists a wealth of artifact-free, high quality CT images with vertebra annotations. This motivates us to build a CBCT vertebra segmentation model using unpaired CT images with annotations. To overco…
Images captured in the low-light condition suffer from low visibility and various imaging artifacts, e.g., real noise. Existing supervised enlightening algorithms require a large set of pixel-aligned training image pairs, which are hard to prepare in practice. Though weakly-supervised or unsupervised methods can alleviate such challenges without using paired training images, some real-world artifacts inevitably get falsely amplified because of the lack of corresponded supervision. In this paper, instead of using perfectly aligned images for training, we creatively employ the misaligned real-wo…
HACA3: A Unified Approach for Multi-site MR Image Harmonization
Johns Hopkins University（约翰斯·霍普金斯大学）；National Institute on Aging, National Institutes of Health（美国国立卫生研究院国家老龄化研究所）；Johns Hopkins School of Medicine（约翰斯·霍普金斯大学医学院）
PANDORA: Pixel-wise Attention Dissolution and Latent Guidance for Zero-Shot Object Removal
University of Science, Ho Chi Minh City, Vietnam（越南胡志明市理科大学）；Vietnam National University, Ho Chi Minh City, Vietnam（越南胡志明市国家大学）；University of Dayton, Ohio, United States（美国俄亥俄州代顿大学）
Korea Advanced Institute of Science and Technology (KAIST)（韩国科学技术院）
Metal artifact reduction (MAR) is one of the most important research topics in computed tomography (CT). With the advance of deep learning technology for image reconstruction,various deep learning methods have been also suggested for metal artifact removal, among which supervised learning methods are most popular. However, matched non-metal and metal image pairs are difficult to obtain in real CT acquisition. Recently, a promising unsupervised learning for MAR was proposed using feature disentanglement, but the resulting network architecture is complication and difficult to handle large size c…
With the excellent disentanglement properties of state-of-the-art generative models, image editing has been the dominant approach to control the attributes of synthesised face images. However, these edited results often suffer from artifacts or incorrect feature rendering, especially when there is a large discrepancy between the image to be edited and the desired feature set. Therefore, we propose a new approach to mapping the latent vectors of the generative model to the scaling factors through solving a set of multivariate linear equations. The coefficients of the equations are the eigenvect…
Z 2 Sky Technologies Inc.（Z 2 天空科技公司）；Beijing University of Posts and Telecommunications（北京邮电大学）；Johns Hopkins University（约翰斯·霍普金斯大学）；Suzhou Institute for Advance Research, University of Science and Technology of China（中国科学技术大学苏州研究院）；Key Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS（中国科学院计算技术研究所中国科学院智能信息处理重点实验室）
Recently, both supervised and unsupervised deep learning methods have been widely applied on the CT metal artifact reduction (MAR) task. Supervised methods such as Dual Domain Network (Du-DoNet) work well on simulation data; however, their performance on clinical data is limited due to domain gap. Unsupervised methods are more generalized, but do not eliminate artifacts completely through the sole processing on the image domain. To combine the advantages of both MAR methods, we propose an unpaired dual-domain network (U-DuDoNet) trained using unpaired data. Unlike the artifact disentanglement …
The Chinese University of Hong Kong（香港中文大学）；The Chinese University of Hong Kong, Shenzhen（香港中文大学（深圳））
Despite the recent advance of Generative Adversarial Networks (GANs) in high-fidelity image synthesis, there lacks enough understanding of how GANs are able to map a latent code sampled from a random distribution to a photo-realistic image. Previous work assumes the latent space learned by GANs follows a distributed representation but observes the vector arithmetic phenomenon. In this work, we propose a novel framework, called InterFaceGAN, for semantic face editing by interpreting the latent semantics learned by GANs. In this framework, we conduct a detailed study on how different semantics a…
One of the biggest challenges for deep learning algorithms in medical image analysis is the indiscriminate mixing of image properties, e.g. artifacts and anatomy. These entangled image properties lead to a semantically redundant feature encoding for the relevant task and thus lead to poor generalization of deep learning algorithms. In this paper we propose a novel representation disentanglement method to extract semantically meaningful and generalizable features for different tasks within a multi-task learning framework. Deep neural networks are utilized to ensure that the encoded features are…
Although 2D generative models have made great progress in face image generation and animation, they often suffer from undesirable artifacts such as 3D inconsistency when rendering images from different camera viewpoints. This prevents them from synthesizing video animations indistinguishable from real ones. Recently, 3D-aware GANs extend 2D GANs for explicit disentanglement of camera pose by leveraging 3D scene representations. These methods can well preserve the 3D consistency of the generated images across different views, yet they cannot achieve fine-grained control over other attributes, a…
Adverse weather image translation belongs to the unsupervised image-to-image (I2I) translation task which aims to transfer adverse condition domain (eg, rainy night) to standard domain (eg, day). It is a challenging task because images from adverse domains have some artifacts and insufficient information. Recently, many studies employing Generative Adversarial Networks (GANs) have achieved notable success in I2I translation but there are still limitations in applying them to adverse weather enhancement. Symmetric architecture based on bidirectional cycle-consistency loss is adopted as a standa…
Helmholtz AI（亥姆霍兹AI）；Helmholtz Center Munich（慕尼黑亥姆霍兹中心）；Klinikum Rechts der Isar（右岸医院）；Technical University of Munich (TUM)（慕尼黑工业大学）
In recent years, data-driven machine learning (ML) methods have revolutionized the computer vision community by providing novel efficient solutions to many unsolved (medical) image analysis problems. However, due to the increasing privacy concerns and data fragmentation on many different sites, existing medical data are not fully utilized, thus limiting the potential of ML. Federated learning (FL) enables multiple parties to collaboratively train a ML model without exchanging local data. However, data heterogeneity (non-IID) among the distributed clients is yet a challenge. To this end, we pro…
