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arXiv 1908.00768cond-mat.soft
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活性物质侵入

Active Matter Invasion

Felix Kempf, Romain Mueller, Erwin Frey, Julia M. Yeomans, Amin Doostmohammadi

摘要:

生物活性物质如细菌生物膜和真核细胞在有限的微空间中茁壮成长。在这里,我们通过数值模拟表明,限制可以作为一个机械的指导,以实现不同的集体入侵模式时,结合生长动力学和生物材料的内在活性。我们评估不断增长的界面的动态,并根据不断增长的物质的组成粒子的活动对这些集体入侵模式进行分类。虽然在小的和中等的活动,活性材料作为一个连贯的单元增长,我们发现,活性材料的斑点集体脱离以上的一个明确定义的活动阈值的队列。我们进一步研究了不同入侵模式之间交叉的机械机制,并量化了它们对整体入侵速度的影响。

英文摘要:

Biological active materials such as bacterial biofilms and eukaryotic cells thrive in confined micro-spaces. Here, we show through numerical simulations that confinement can serve as a mechanical guidance to achieve distinct modes of collective invasion when combined with growth dynamics and the intrinsic activity of biological materials. We assess the dynamics of the growing interface and classify these collective modes of invasion based on the activity of the constituent particles of the growing matter. While at small and moderate activities the active material grows as a coherent unit, we find that blobs of active material collectively detach from the cohort above a well-defined activity threshold. We further characterise the mechanical mechanisms underlying the crossovers between different modes of invasion and quantify their impact on the overall invasion speed.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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