During training phase, more connections (e.g. channel concatenation in last layer of DenseNet) means more occupied GPU memory and lower GPU utilization, requiring more training time. The increase of training time is also not conducive to launch application of SR algorithms. This's why we abandoned DenseNet as basic network. Futhermore, we abandoned this paper due to its limitation only applied on medical images.
Please view our lastest work applied on general images at arXiv:1911.03464.
The University of Tokyo（东京大学）；LPIXEL Inc.（LPIXEL公司）；National Institute of Informatics（国立信息学研究所）；University of Cambridge（剑桥大学）；Keio University（庆应义塾大学）
Despite the success of Convolutional Neural Network-based Computer-Aided Diagnosis research, its clinical applications remain challenging. Accordingly, developing medical Artificial Intelligence (AI) fitting into a clinical environment requires identifying/bridging the gap between AI and Healthcare sides. Since the biggest problem in Medical Imaging lies in data paucity, confirming the clinical relevance for diagnosis of research-proven image augmentation techniques is essential. Therefore, we hold a clinically valuable AI-envisioning workshop among Japanese Medical Imaging experts, physicians…
Beijing Institute of Technology（北京理工大学）；Xuanwu Hospital, Capital Medical University（首都医科大学宣武医院）；National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College（中国医学科学院北京协和医学院肿瘤医院（国家癌症中心/国家肿瘤临床医学研究中心））
Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a novel deep learning-based method for fusing Magnetic Resonance Imaging (MRI)/Computed Tomography (CT) images and clinical information for diagnostic tasks. Two paths of neural layers are performed to extract image features and clinical features, respectively, and at the same time clinical features are employed as the attention to guide the extraction of imag…
Samsung Medical Center（三星医疗中心）；Sungkyunkwan University School of Medicine（成均馆大学医学院）；Sungkyunkwan University（成均馆大学）
The cone-beam computed tomography (CBCT) provides 3D volumetric imaging of a target with low radiation dose and cost compared with conventional computed tomography, and it is widely used in the detection of paranasal sinus disease. However, it lacks the sensitivity to detect soft tissue lesions owing to reconstruction constraints. Consequently, only physicians with expertise in CBCT reading can distinguish between inherent artifacts or noise and diseases, restricting the use of this imaging modality. The development of artificial intelligence (AI)-based computer-aided diagnosis methods for CBC…
A Synthetic Data-Driven Radiology Foundation Model for Pan-tumor Clinical Diagnosis
Shanghai Jiao Tong University（上海交通大学）；Shanghai AI Lab（上海人工智能实验室）；The First Hospital of China Medical University（中国医科大学附属第一医院）；Harvard Medical School（哈佛医学院）
National Institute of Technology Karnataka Surathkal（卡纳塔克邦国家技术学院苏拉特卡尔分校）
In clinical diagnosis, diagnostic images that are obtained from the scanning devices serve as preliminary evidence for further investigation in the process of delivering quality healthcare. However, often the medical image may contain fault artifacts, introduced due to noise, blur and faulty equipment. The reason for this may be the low-quality or older scanning devices, the test environment or technicians lack of training etc; however, the net result is that the process of fast and reliable diagnosis is hampered. Resolving these issues automatically can have a significant positive impact in a…
Nagoya Institute of Technology（名古屋工业大学）；RIKEN Center for Advanced Intelligence Project（理化学研究所先进智能项目中心）；Kurume University School of Medicine（久留米大学医学院）；Nagoya University（名古屋大学）
In medical image diagnosis, identifying the attention region, i.e., the region of interest for which the diagnosis is made, is an important task. Various methods have been developed to automatically identify target regions from given medical images. However, in actual medical practice, the diagnosis is made based not only on the images but also on a variety of clinical records. This means that pathologists examine medical images with some prior knowledge of the patients and that the attention regions may change depending on the clinical records. In this study, we propose a method called the Pe…
GMENet: Generative Mixture of Experts Network for Multi-Center Glioma Diagnosis with Incomplete Imaging Sequences
School of Biomedical Engineering and Technology Innovation, Fudan University（复旦大学生物医学工程与技术创新学院）；Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University（复旦大学脑启发智能科学技术研究院）；Intelligent Diagnosis and Treatment Laboratory for Brain Diseases, Joint Laboratory of Neurosurgery Department of Huashan Hospital and School of Information Science and Technology, Fudan University（脑病智能诊断与治疗实验室，华山医院神经外科部门联合实验室，复旦大学信息科学学院）
A Comprehensive Review of Techniques, Algorithms, Advancements, Challenges, and Clinical Applications of Multi-modal Medical Image Fusion for Improved Diagnosis
Interdisciplinary Research Center for Finance and Digital Economy, King Fahd University of Petroleum and Minerals（金融与数字经济交叉研究中心，国王法赫德石油和矿物大学）；Department of Software Engineering, Faculty of Information Technology, Al-Ahliyya Amman University（软件工程系，信息科技学院，阿尔阿赫利亚大学）；Department of Information Systems and Operations Management, King Fahd University of Petroleum and Minerals（信息系统与运营管理系，国王法赫德石油和矿物大学）；ADAPT Research Centre, School of Computer Science, University of Galway（ADAPT研究中心，计算机科学学院，Galway大学）；Department of Mechanical and Nuclear Engineering, Khalifa University（机械与核工程系，哈利法大学）
Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical licensing exam. However, LLMs currently have difficulty processing images, making it challenging to interpret information from medical images, which are rich in information that supports clinical decisions. On the other hand, computer-aided diagnosis (CAD) networks for medical images have seen significant success in the medical field by using advanced deep-le…
One of the critical tools for early detection and subsequent evaluation of the incidence of lung diseases is chest radiography. This study presents a real-world implementation of a convolutional neural network (CNN) based Carebot Covid app to detect COVID-19 from chest X-ray (CXR) images. Our proposed model takes the form of a simple and intuitive application. Used CNN can be deployed as a STOW-RS prediction endpoint for direct implementation into DICOM viewers. The results of this study show that the deep learning model based on DenseNet and ResNet architecture can detect SARS-CoV-2 from CXR …
In Zambia, there is a serious shortage of medical staff where each practitioner attends to about 17000 patients in a given district while still, other patients travel over 10 km to access the basic medical services. In this research, we implement a deep learning model that can perform the clinical diagnosis process. The study will prove whether image analysis is capable of performing clinical diagnosis. It will also enable us to understand if we can use image analysis to lessen the workload on medical practitioners by delegating some tasks to an AI. The success of this study has the potential …
Fraunhofer Institute for Integrated Circuits IIS（弗劳恩霍夫集成电路研究所）；Ludwig Maximilian University of Munich（慕尼黑大学）
Unlabeled data is often abundant in the clinic, making machine learning methods based on semi-supervised learning a good match for this setting. Despite this, they are currently receiving relatively little attention in medical image analysis literature. Instead, most practitioners and researchers focus on supervised or transfer learning approaches. The recently proposed MixMatch and FixMatch algorithms have demonstrated promising results in extracting useful representations while requiring very few labels. Motivated by these recent successes, we apply MixMatch and FixMatch in an ophthalmologic…
Dartmouth College（达特茅斯学院）；Dartmouth-Hitchcock Medical Center（达特茅斯-希区柯克医疗中心）；Geisel School of Medicine（盖塞尔医学院）；Metrohealth System（都会医疗系统）；Case Western Reserve University（凯斯西储大学）
Recently, there has been great interest in developing Artificial Intelligence (AI) enabled computer-aided diagnostics solutions for the diagnosis of skin cancer. With the increasing incidence of skin cancers, low awareness among a growing population, and a lack of adequate clinical expertise and services, there is an immediate need for AI systems to assist clinicians in this domain. A large number of skin lesion datasets are available publicly, and researchers have developed AI-based image classification solutions, particularly deep learning algorithms, to distinguish malignant skin lesions fr…
Ontology-based knowledge representation for bone disease diagnosis: a foundation for safe and sustainable medical artificial intelligence systems
University of Science, VNUHCM（胡志明市国家大学科学大学）；Viet Nam National University, Ho Chi Minh City（越南国家大学胡志明市分校）；Ho Chi Minh City Hospital for Traumatology and Orthopedics（胡志明市创伤与骨科医院）
Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided diagnosis (CAD) systems have been proposed to assist this process. However, most of them do not provide the reasoning of their classification process, which may jeopardize their credibility in practical use. To overcome this, we propose a novel deep learning framework called multi-attribute attention network (MAA-Net) that is designed to mimic the clinical diagn…
Deep learning methods for ophthalmic diagnosis have shown considerable success in tasks like segmentation and classification. However, their widespread application is limited due to the models being opaque and vulnerable to making a wrong decision in complicated cases. Explainability methods show the features that a system used to make prediction while uncertainty awareness is the ability of a system to highlight when it is not sure about the decision. This is one of the first studies using uncertainty and explanations for informed clinical decision making. We perform uncertainty analysis of a…
Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel multimodal deep learning framework to aid medical professionals in AD diagnosis. We present a Multimodal Alzheimer's Disease Diagnosis framework (MADDi) to accurately detect the presence of AD and mild cognitive impairment (MCI) from imaging, genetic, and clinical data. MADDi is novel in that we use cross-modal attention, which captures interactions between moda…
Hong Kong Baptist University（香港浸会大学）；Harbin Institute of Technology（哈尔滨工业大学）；The University of Hong Kong - Shenzhen Hospital（香港大学深圳医院）；Shenzhen Yiyuan Intelligent Technology Co., Ltd.（深圳怡园智能科技有限公司）
Skin disease is one of the most common types of human diseases, which may happen to everyone regardless of age, gender or race. Due to the high visual diversity, human diagnosis highly relies on personal experience; and there is a serious shortage of experienced dermatologists in many countries. To alleviate this problem, computer-aided diagnosis with state-of-the-art (SOTA) machine learning techniques would be a promising solution. In this paper, we aim at understanding the performance of convolutional neural network (CNN) based approaches. We first build two versions of skin disease datasets…
Peking University Third Hospital（北京大学第三医院）；Engineering Research Center of Bone and Joint Precision Medicine, Ministry of Education（教育部骨关节精准医学工程研究中心）；University of Toronto（多伦多大学）
As the first diagnostic imaging modality of avascular necrosis of the femoral head (AVNFH), accurately staging AVNFH from a plain radiograph is critical yet challenging for orthopedists. Thus, we propose a deep learning-based AVNFH diagnosis system (AVN-net). The proposed AVN-net reads plain radiographs of the pelvis, conducts diagnosis, and visualizes results automatically. Deep convolutional neural networks are trained to provide an end-to-end diagnosis solution, covering tasks of femoral head detection, exam-view identification, side classification, AVNFH diagnosis, and key clinical notes g…
Designing a Deep Learning-Driven Resource-Efficient Diagnostic System for Metastatic Breast Cancer: Reducing Long Delays of Clinical Diagnosis and Improving Patient Survival in Developing Countries
University of Maryland, Baltimore County（马里兰大学巴尔的摩县分校）；Meta Platforms Inc.（元平台公司）
Vrije Universiteit（阿姆斯特丹自由大学）；Amsterdam UMC（阿姆斯特丹大学医学中心）；Amsterdam Neuroscience（阿姆斯特丹神经科学研究所）；Erasmus MC（伊拉斯姆斯医学中心）；University College London（伦敦大学学院）；TU Delft（代尔夫特理工大学）
Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their working, their input data - such as cognitive tests, imaging and genetic data - and the types of output they provide. We will focus on specific use cases for diagnosis, i.e. estimating the current 'condition' of the patient, such as early detection and diagnosis of dementia, differential diagnosis of brain tumours, and decision making in stroke. Regarding predic…
CBIDR: A novel method for information retrieval combining image and data by means of TOPSIS applied to medical diagnosis
Labcin - Nature-inspired computing Lab. - Federal University of Espírito Santo - Vitória, ES, Brazil（自然启发计算实验室 - 芬斯大学 - 维蒂利亚）；Graduate Program in Computer Science, PPGI, UFES - Federal University of Espírito Santo - Vitória, ES, Brazil（计算机科学研究生项目，PPGI，UFES - 芬斯大学 - 维蒂利亚）
Endomicroscopy is indispensable for minimally invasive diagnostics in clinical practice. For optical keyhole monitoring of surgical interventions, high-resolution fiber endoscopic imaging is considered to be very promising, especially in combination with label-free imaging techniques to realize in vivo diagnosis. However, the inherent honeycomb-artifacts of coherent fiber bundles (CFB) reduce the resolution and limit the clinical applications. We propose an end-to-end lensless fiber imaging scheme toward intraoperative real-time cancer diagnosis. The framework includes resolution enhancement a…
