Accurate segmentation of the prostate from magnetic resonance (MR) images provides useful information for prostate cancer diagnosis and treatment. However, automated prostate segmentation from 3D MR images still faces several challenges. For instance, a lack of clear edge between the prostate and other anatomical structures makes it challenging to accurately extract the boundaries. The complex background texture and large variation in size, shape and intensity distribution of the prostate itself make segmentation even further complicated. With deep learning, especially convolutional neural networks (CNNs), emerging as commonly used methods for medical image segmentation, the difficulty in obtaining large number of annotated medical images for training CNNs has become much more pronounced that ever before. Since large-scale dataset is one of the critical components for the success of deep learning, lack of sufficient training data makes it difficult to fully train complex CNNs. To tackle the above challenges, in this paper, we propose a boundary-weighted domain adaptive neural network (BOWDA-Net). To make the network more sensitive to the boundaries during segmentation, a boundary-weighted segmentation loss (BWL) is proposed. Furthermore, an advanced boundary-weighted transfer leaning approach is introduced to address the problem of small medical imaging datasets. We evaluate our proposed model on the publicly available MICCAI 2012 Prostate MR Image Segmentation (PROMISE12) challenge dataset. Our experimental results demonstrate that the proposed model is more sensitive to boundary information and outperformed other state-of-the-art methods.
East China University of Science and Technology（华东理工大学）
Prostate cancer is one of the common diseases in men, and it is the most common malignant tumor in developed countries. Studies have shown that the male prostate incidence rate is as high as 2.5% to 16%, Currently, the inci-dence of prostate cancer in Asia is lower than that in the West, but it is increas-ing rapidly. If prostate cancer can be found as early as possible and treated in time, it will have a high survival rate. Therefore, it is of great significance for the diagnosis and treatment of prostate cancer. In this paper, we propose a trans-fer learning method based on deep neural netwo…
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；University of Chinese Academy of Sciences（中国科学院大学）；Peng Cheng Laboratory（鹏城实验室）；University of Gezira（杰济拉大学）
Volumetric magnetic resonance (MR) image segmentation plays an important role in many clinical applications. Deep learning (DL) has recently achieved state-of-the-art or even human-level performance on various image segmentation tasks. Nevertheless, manually annotating volumetric MR images for DL model training is labor-exhaustive and time-consuming. In this work, we aim to train a semi-supervised and self-supervised collaborative learning framework for prostate 3D MR image segmentation while using extremely sparse annotations, for which the ground truth annotations are provided for just the c…
The Chinese University of Hong Kong（香港中文大学）；Shenzhen University（深圳大学）；The Hong Kong Polytechnic University（香港理工大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Boundary incompleteness raises great challenges to automatic prostate segmentation in ultrasound images. Shape prior can provide strong guidance in estimating the missing boundary, but traditional shape models often suffer from hand-crafted descriptors and local information loss in the fitting procedure. In this paper, we attempt to address those issues with a novel framework. The proposed framework can seamlessly integrate feature extraction and shape prior exploring, and estimate the complete boundary with a sequential manner. Our framework is composed of three key modules. Firstly, we seria…
Institute of Computer Science, FORTH（福拉什计算机科学研究所）；Hellenic Mediterranean University（希腊地中海大学）；University of Ioannina（约阿尼纳大学）
Prostate segmentation from magnetic resonance imaging (MRI) is a challenging task. In recent years, several network architectures have been proposed to automate this process and alleviate the burden of manual annotation. Although the performance of these models has achieved promising results, there is still room for improvement before these models can be used safely and effectively in clinical practice. One of the major challenges in prostate MR image segmentation is the presence of class imbalance in the image labels where the background pixels dominate over the prostate. In the present work …
Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to delineate and classify the cancerous patterns in the tissue via computer-vision algorithms in order to support the physicians' task. The methodological core of this work is a U-Net convolutional neural network for image segmentation modified with residual blocks able to segment cancerous tissue according to the full Gleason system. This model outperforms othe…
We hypothesize that probabilistic voxel-level classification of anatomy and malignancy in prostate MRI, although typically posed as near-identical segmentation tasks via U-Nets, require different loss functions for optimal performance due to inherent differences in their clinical objectives. We investigate distribution, region and boundary-based loss functions for both tasks across 200 patient exams from the publicly-available ProstateX dataset. For evaluation, we conduct a thorough comparative analysis of model predictions and calibration, measured with respect to multi-class volume segmentat…
Southern University of Science and Technology（南方科技大学）；The University of Hong Kong（香港大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；The University of Waikato（怀卡托大学）
In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper network usually has a better generalization ability because of more learnable parameters. Secondly, the exponential ReLU (ELU), as an alternative of ReLU, is not much different from ReLU when the network of interest gets deep. Thirdly, the Dice loss, as one of the pervasive loss functions for medical image segmentation, is not effective when the prediction is …
Deep Attentive Features for Prostate Segmentation in 3D Transrectal Ultrasound
Shenzhen University（深圳大学）；The Chinese University of Hong Kong（香港中文大学）；The Hong Kong Polytechnic University（香港理工大学）；Sun Yat-Sen University（中山大学）；the First Affiliated Hospital（第一附属医院）
Tecnologico de Monterrey（蒙特雷科技大学）；CIATEQ A.C.（CIATEQ先进技术中心）；Universitat Politècnica de Catalunya（加泰罗尼亚理工大学）；Hospital Sant Joan de Déu（圣胡安德迪奥斯医院）
Prostate cancer is the second-most frequently diagnosed cancer and the sixth leading cause of cancer death in males worldwide. The main problem that specialists face during the diagnosis of prostate cancer is the localization of Regions of Interest (ROI) containing a tumor tissue. Currently, the segmentation of this ROI in most cases is carried out manually by expert doctors, but the procedure is plagued with low detection rates (of about 27-44%) or overdiagnosis in some patients. Therefore, several research works have tackled the challenge of automatically segmenting and extracting features o…
MCICSAM: Monte Carlo-guided Interpolation Consistency Segment Anything Model for Semi-Supervised Prostate Zone Segmentation
College of Medicine and Biological Information Engineering, Northeastern University（东北大学医学与生物信息工程学院）；Shengjing Hospital of China Medical University（中国医科大学附属盛京医院）；University of Chicago（芝加哥大学）；University of Dundee（邓迪大学）；School of Health Management, China Medical University（中国医科大学健康管理学院）
Prostate cancer is one of the main diseases affecting men worldwide. The Gleason scoring system is the primary diagnostic tool for prostate cancer. This is obtained via the visual analysis of cancerous patterns in prostate biopsies performed by expert pathologists, and the aggregation of the main Gleason grades in a combined score. Computer-aided diagnosis systems allow to reduce the workload of pathologists and increase the objectivity. Recently, efforts have been made in the literature to develop algorithms aiming the direct estimation of the global Gleason score at biopsy/core level with gl…
Accurate segmentation of prostate and surrounding organs at risk is important for prostate cancer radiotherapy treatment planning. We present a fully automated workflow for male pelvic CT image segmentation using deep learning. The architecture consists of a 2D localization network followed by a 3D segmentation network for volumetric segmentation of prostate, bladder, rectum, and femoral heads. We used a multi-channel 2D U-Net followed by a 3D U-Net with encoding arm modified with aggregated residual networks, known as ResNeXt. The models were trained and tested on a pelvic CT image dataset co…
Khalifa University（哈利法大学）；Beihang University（北京航空航天大学）；University of Louisville（路易斯维尔大学）
Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues \RV{(patch-wise) in order to grade PCa from the whole slide images (WSI).} Also, the proposed approach encompasses two main contributions: 1) A synergy of hybrid dilation factors and hierarchical decomposition of latent space representation for effective Gleason tissues extraction, and 2) A three-tiered loss function which can penalize different semantic seg…
Empirical Analysis of a Segmentation Foundation Model in Prostate Imaging
Weill Cornell Medicine（威尔康奈尔医学院）；Martinos Center for Biomedical Imaging, Massachusetts General Hospital（麻省总医院马丁诺斯生物医学成像中心）；Harvard Medical School（哈佛医学院）；Massachusetts Institute of Technology（麻省理工学院）；Cornell University（康奈尔大学）；Cornell Tech（康奈尔理工学院）
Automated segmentation can assist radiotherapy treatment planning by saving manual contouring efforts and reducing intra-observer and inter-observer variations. The recent development of deep learning approaches has revoluted medical data processing, including semantic segmentation, by dramatically improving performance. However, training effective deep learning models usually require a large amount of high-quality labeled data, which are often costly to collect. We developed a novel semi-supervised adversarial deep learning approach for 3D pelvic CT image semantic segmentation. Unlike supervi…
Washington University（华盛顿大学）；Washington University School of Medicine（华盛顿大学医学院）
Purpose: The research is to develop a novel CNN-based adversarial deep learning method to improve and expedite the multi-organ semantic segmentation of CT images, and to generate accurate contours on pelvic CT images. Methods: Planning CT and structure datasets for 120 patients with intact prostate cancer were retrospectively selected and divided for 10-fold cross-validation. The proposed adversarial multi-residual multi-scale pooling Markov Random Field (MRF) enhanced network (ARPM-net) implements an adversarial training scheme. A segmentation network and a discriminator network were trained …
City University of Hong Kong（香港城市大学）；University College London（伦敦大学学院）
Dice similarity coefficient (DSC) and Hausdorff distance (HD) are widely used for evaluating medical image segmentation. They have also been criticised, when reported alone, for their unclear or even misleading clinical interpretation. DSCs may also differ substantially from HDs, due to boundary smoothness or multiple regions of interest (ROIs) within a subject. More importantly, either metric can also have a nonlinear, non-monotonic relationship with outcomes based on Type 1 and 2 errors, designed for specific clinical decisions that use the resulting segmentation. Whilst cases causing disagr…
Fully convolutional networks (FCNs), including UNet and VNet, are widely-used network architectures for semantic segmentation in recent studies. However, conventional FCN is typically trained by the cross-entropy or Dice loss, which only calculates the error between predictions and ground-truth labels for pixels individually. This often results in non-smooth neighborhoods in the predicted segmentation. To address this problem, we propose a two-stage framework, with the first stage to quickly localize the prostate region and the second stage to precisely segment the prostate by a multi-task UNe…
Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires accurate prostate segmentation in TRUS images. To achieve this, this study uses a novel residual connection based fully convolutional network. The advantage of this segmentation technique is that it requires no pre-processing of TRUS images to perform the segmentation. Thus, it offers a faster and straightforward prostate segmentation from TRUS images. Results s…
Northwestern Polytechnical University（西北工业大学）；University of Sydney（悉尼大学）；University of Pittsburgh（匹兹堡大学）；Royal Prince Alfred Hospital（皇家阿尔弗雷德亲王医院）
Advanced deep learning methods have been developed to conduct prostate MR volume segmentation in either a 2D or 3D fully convolutional manner. However, 2D methods tend to have limited segmentation performance, since large amounts of spatial information of prostate volumes are discarded during the slice-by-slice segmentation process; and 3D methods also have room for improvement, since they use isotropic kernels to perform 3D convolutions whereas most prostate MR volumes have anisotropic spatial resolution. Besides, the fully convolutional structural methods achieve good performance for localiz…
University Hospital of Marburg (UKGM)（马尔堡大学医院 (UKGM)）
Prostate cancer is the most abundant cancer in men, with over 200,000 expected new cases and around 28,000 deaths in 2012 in the US alone. In this study, the segmentation results for the prostate central gland (PCG) in MR scans are presented. The aim of this research study is to apply a graph-based algorithm to automated segmentation (i.e. delineation) of organ limits for the prostate central gland. The ultimate goal is to apply automated segmentation approach to facilitate efficient MR-guided biopsy and radiation treatment planning. The automated segmentation algorithm used is graph-driven ba…
The size and geometry of the prostate are known to be pivotal quantities used by clinicians to assess the condition of the gland during prostate cancer screening. As an alternative to palpation, an increasing number of methods for estimation of the above-mentioned quantities are based on using imagery data of prostate. The necessity to process large volumes of such data creates a need for automatic segmentation tools which would allow the estimation to be carried out with maximum accuracy and efficiency. In particular, the use of transrectal ultrasound (TRUS) imaging in prostate cancer screeni…
Wuhan University（武汉大学）；National Cancer Institute（国家癌症研究所）；National Institutes of Health（美国国立卫生研究院）；Philips Research（飞利浦研究院）
Prostate segmentation from Magnetic Resonance (MR) images plays an important role in image guided interven- tion. However, the lack of clear boundary specifically at the apex and base, and huge variation of shape and texture between the images from different patients make the task very challenging. To overcome these problems, in this paper, we propose a deeply supervised convolutional neural network (CNN) utilizing the convolutional information to accurately segment the prostate from MR images. The proposed model can effectively detect the prostate region with additional deeply supervised laye…
The Chinese University of Hong Kong（香港中文大学）；University of Cambridge（剑桥大学）；Inception Institute of Artificial Intelligence（启迪人工智能研究院）；The Hong Kong University of Science and Technology（香港科技大学）；Jinan University（暨南大学）；Southern University of Science and Technology（南方科技大学）；Chinese Academy of Sciences（中国科学院）
Automatic breast lesion segmentation in ultrasound helps to diagnose breast cancer, which is one of the dreadful diseases that affect women globally. Segmenting breast regions accurately from ultrasound image is a challenging task due to the inherent speckle artifacts, blurry breast lesion boundaries, and inhomogeneous intensity distributions inside the breast lesion regions. Recently, convolutional neural networks (CNNs) have demonstrated remarkable results in medical image segmentation tasks. However, the convolutional operations in a CNN often focus on local regions, which suffer from limit…
The high incidence rate of prostate disease poses a requirement in early detection for diagnosis. As one of the main imaging methods used for prostate cancer detection, Magnetic Resonance Imaging (MRI) has wide range of appearance and imbalance problems, making automated prostate segmentation fundamental but challenging. Here we propose a novel Densely Dilated Spatial Pooling Convolutional Network (DDSP ConNet) in encoder-decoder structure. It employs dense structure to combine dilated convolution and global pooling, thus supplies coarse segmentation results from encoder and decoder subnet and…
Continual atlas-based segmentation of prostate MRI
Technical University of Darmstadt（达姆施塔特工业大学）；Stanford University（斯坦福大学）；University of Cologne（科隆大学）；University of Frankfurt（法兰克福大学）；University Medical Center Mainz（美因茨大学医学中心）
Prostate cancer (PCa) is the most common cancer in men in the United States. Multiparametic magnetic resonance imaging (mp-MRI) has been explored by many researchers to targeted prostate biopsies and radiation therapy. However, assessment on mp-MRI can be subjective, development of computer-aided diagnosis systems to automatically delineate the prostate gland and the intraprostratic lesions (ILs) becomes important to facilitate with radiologists in clinical practice. In this paper, we first study the implementation of the Mask-RCNN model to segment the prostate and ILs. We trained and evaluate…
Radboud University Medical Centre Nijmegen（拉德堡德大学奈梅亨医学中心）
Convolutional networks have become state-of-the-art techniques for automatic medical image analysis, with the U-net architecture being the most popular at this moment. In this article we report the application of a 3D version of U-net to the automatic segmentation of prostate peripheral and transition zones in 3D MRI images. Our results are slightly better than recent studies that used 2D U-net and handcrafted feature approaches. In addition, we test ideas for improving the 3D U-net setup, by 1) letting the network segment surrounding tissues, making use of the fixed anatomy, and 2) adjusting …
The Chinese University of Hong Kong（香港中文大学）；Chinese Academy of Sciences（中国科学院）
Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e., learning a model from multi-domain source data such that it can directly generalize to an unseen target domain. We present a novel shape-aware meta-learning scheme to improve the model generalization in prostate MRI segmentation. Our learning scheme roots in the gradient-based meta-learning, by explicitly simulating domain shift with virtual meta-train and m…
University of California, Los Angeles (UCLA)（加利福尼亚大学洛杉矶分校）；The First Affiliated Hospital of China Medical University（中国医科大学附属第一医院）；VoxelCloud, Inc.（体素云公司）
Prostate cancer is the second leading cause of cancer death among men in the United States. The diagnosis of prostate MRI often relies on the accurate prostate zonal segmentation. However, state-of-the-art automatic segmentation methods often fail to produce well-contained volumetric segmentation of the prostate zones since certain slices of prostate MRI, such as base and apex slices, are harder to segment than other slices. This difficulty can be overcome by accounting for the cross-slice relationship of adjacent slices, but current methods do not fully learn and exploit such relationships. I…
3D EAGAN: 3D edge-aware attention generative adversarial network for prostate segmentation in transrectal ultrasound images
Nanchang Hangkong University（南昌航空大学）；Nanjing University of Information Science and Technology（南京信息工程大学）；The First Affiliated Hospital of Nanchang University（南昌大学第一附属医院）
Histopathological Spectrum-Guided Prostate Stratification via Segmentation-Assisted Diagnostic Transformer
College of Artificial Intelligence, Nankai University（南开大学人工智能学院）；Tianjin First Central Hospital（天津市第一中心医院）；School of Electronics and Information Engineering, Tiangong University（天津工业大学电子与信息工程学院）；School of Artificial Intelligence, Hebei University of Technology（河北工业大学人工智能学院）；North China Digital Health Technology Co., Ltd.（华北数字健康科技有限公司）；School of Computing and Information Systems, Singapore Management University（新加坡管理大学计算与信息系统学院）
Manchester Metropolitan University（曼彻斯特城市大学）；NHS（英国国民保健署）；The Leeds Teaching Hospital（利兹教学医院）；The Clatterbridge Cancer Center（克莱特布里奇癌症中心）；Leicester University（莱斯特大学）
Prostate radiotherapy is a well established curative oncology modality, which in future will use Magnetic Resonance Imaging (MRI)-based radiotherapy for daily adaptive radiotherapy target definition. However the time needed to delineate the prostate from MRI data accurately is a time consuming process. Deep learning has been identified as a potential new technology for the delivery of precision radiotherapy in prostate cancer, where accurate prostate segmentation helps in cancer detection and therapy. However, the trained models can be limited in their application to clinical setting due to di…
Radboud University Medical Center（拉德堡德大学医学中心）；Fraunhofer MEVIS（弗劳恩霍夫医学图像计算研究所）
Prostate cancer (PCa) is graded by pathologists by examining the architectural pattern of cancerous epithelial tissue on hematoxylin and eosin (H&E) stained slides. Given the importance of gland morphology, automatically differentiating between glandular epithelial tissue and other tissues is an important prerequisite for the development of automated methods for detecting PCa. We propose a new method, using deep learning, for automatically segmenting epithelial tissue in digitized prostatectomy slides. We employed immunohistochemistry (IHC) to render the ground truth less subjective and more p…
German Cancer Research Center (DKFZ)（德国癌症研究中心）；University of Heidelberg Medical Center（海德堡大学医学中心）
Semantic segmentation constitutes an integral part of medical image analyses for which breakthroughs in the field of deep learning were of high relevance. The large number of trainable parameters of deep neural networks however renders them inherently data hungry, a characteristic that heavily challenges the medical imaging community. Though interestingly, with the de facto standard training of fully convolutional networks (FCNs) for semantic segmentation being agnostic towards the `structure' of the predicted label maps, valuable complementary information about the global quality of the segme…
Segmentation Strategies in Deep Learning for Prostate Cancer Diagnosis: A Comparative Study of Mamba, SAM, and YOLO
School of Electrical Engineering, Iran University of Science and Technology（伊朗科学技术大学电气工程学院）；School of Computer Engineering, Iran University of Science and Technology（伊朗科学技术大学计算机工程学院）；School of Electrical Engineering, Shahrood Branch, Islamic Azad University（伊斯兰阿扎德大学沙赫鲁德分校电气工程学院）；Medical Sciences and Technologies Department, Science and Research Branch, Islamic Azad University（伊斯兰阿扎德大学科学研究分支医学与技术系）；Biomedical Engineering Department, School of Electrical Engineering, Iran University of Science and Technology（伊朗科学技术大学电气工程学院生物医学工程系）
Precise determination of target is an essential procedure in prostate interventions, such as the prostate biopsy, lesion detection and targeted therapy. However, the prostate delineation may be tough in some cases due to tissue ambiguity or lack of partial anatomical boundary. To address this problem, we proposed a weakly supervised registration-based framework for the precise prostate segmentation, by combining convolutional neural network (CNN) with statistical shape model (SSM). To obtain the prostate region, an inception-based neural network (SSM-Net) was firstly exploited to predict the m…
In this work we propose to segment the prostate on a challenging dataset of trans-rectal ultrasound (TRUS) images using convolutional neural networks (CNNs) and statistical shape models (SSMs). TRUS is commonly used for a number of image-guided interventions on the prostate. Fast and accurate segmentation on the organ in these images is crucial to planning and fusion with other modalities such as magnetic resonance images (MRIs) . However, TRUS has limited soft tissue contrast and signal to noise ratio which makes the task of segmenting the prostate challenging and subject to inter-observer an…
Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the glandular structural analysis in histology images. Hence, accurate gland detection and segmentation is crucial for a successful prediction. The methodological basis of this work is a prostate gland segmentation based on U-Net convolutional neural network architectures modified with residual and multi-resolution blocks, trained using data augmentation techniques. The residual configuratio…
Springbok, Inc.（斯普林博克公司）；University of Kentucky（肯塔基大学）；University of Virginia（弗吉尼亚大学）
This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on 3D dilated U-Nets with the first stage to localize the prostate and the second stage to obtain an accurate segmentation from cropped images. For data augmentation, we proposed the variable-input method which crops the region of interest with additional random variations. Similar to other deep learning models, the proposed model also faced the challenge of s…
Multi-parametric MR images have been shown to be effective in the non-invasive diagnosis of prostate cancer. Automated segmentation of the prostate eliminates the need for manual annotation by a radiologist which is time consuming. This improves efficiency in the extraction of imaging features for the characterization of prostate tissues. In this work, we propose a fully automated cascaded deep learning architecture with residual blocks, Cascaded MRes-UNET, for segmentation of the prostate gland and the peripheral zone in one pass through the network. The network yields high Dice scores ($0.91…
Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this problem is detected and treated early, there can be a high chance of survival for the patient. One task that helps diagnose prostate cancer is prostate segmentation from magnetic resonance imaging. Manual segmentation performed by clinical experts has its drawbacks such as: the high time and concentration required from observers; and inter- and intra-observer va…
Align then Refine: Text-Guided 3D Prostate Lesion Segmentation
Department of Radiology, Northwestern University, Chicago, USA（放射科，西北大学，芝加哥，美国）；Department of Urology, Northwestern University, Chicago, USA（泌尿科，西北大学，芝加哥，美国）；Center for Cancer Research, National Cancer Institute, Bethesda, USA（癌症研究中心，国家癌症研究所，贝塞斯达，美国）
Université de Bourgogne Franche-Comté（勃艮第-弗朗什孔泰大学）；CGFL（CGFL（第戎乔治·弗朗索瓦·勒克莱尔中心））；University Hospital of Dijon（第戎大学医院）
Deep learning has shown unprecedented success in a variety of applications, such as computer vision and medical image analysis. However, there is still potential to improve segmentation in multimodal images by embedding prior knowledge via learning-based shape modeling and registration to learn the modality invariant anatomical structure of organs. For example, in radiotherapy automatic prostate segmentation is essential in prostate cancer diagnosis, therapy, and post-therapy assessment from T2-weighted MR or CT images. In this paper, we present a fully automatic deep generative model-driven m…
We propose an automated method for detecting aggressive prostate cancer(CaP) (Gleason score >=7) based on a comprehensive analysis of the lesion and the surrounding normal prostate tissue which has been simultaneously captured in T2-weighted MR images, diffusion-weighted images (DWI) and apparent diffusion coefficient maps (ADC). The proposed methodology was tested on a dataset of 79 patients (40 aggressive, 39 non-aggressive). We evaluated the performance of a wide range of popular quantitative imaging features on the characterization of aggressive versus non-aggressive CaP. We found that a g…
AI-based Automatic Segmentation of Prostate on Multi-modality Images: A Review
Soochow University（苏州大学）；Peking University First Hospital（北京大学第一医院）；Duke Kunshan University（昆山杜克大学）；Swinburne University of Technology（斯威本科技大学）；The Hong Kong Polytechnic University（香港理工大学）；UT Southwestern Medical Center（德克萨斯大学西南医学中心）
An Uncertainty-guided Tiered Self-training Framework for Active Source-free Domain Adaptation in Prostate Segmentation
School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China（电子科技大学机械与电气工程学院）；School of Mathematical Sciences, Harbin Engineering University（哈尔滨工程大学数学科学学院）；Shanghai AI Lab（上海人工智能实验室）；Department of Computer Science and Engineering, The Chinese University of Hong Kong（香港中文大学计算机科学与工程学系）
