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arXiv 1807.07510cs.CV
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基于改进U-Net的MR脑组织图像暗示标注策略

A Strategy of MR Brain Tissue Images' Suggestive Annotation Based on Modified U-Net

Tsinghua University(清华大学);Beijing Sanbo Brain Hospital(北京三博脑科医院);The First Affiliated Hospital of Harbin Medical University(哈尔滨医科大学附属第一医院)

Yang Deng, Yao Sun, Yongpei Zhu, Mingwang Zhu, Wei Han, Kehong Yuan

摘要:

MR脑组织的准确分割是脑异常诊断、手术计划和治疗的关键步骤。然而,这是一项由医学专家执行的耗时的任务。因此,需要自动和可靠的分割方法。如何从有限的标记数据集中选择合适的训练数据集,而不是从整个数据集中选择合适的训练数据集,对于节省训练时间也具有重要意义。另外,由于标注的医学数据非常稀少且价格昂贵,难以广泛获取,因此选择合适的未标注数据集代替所有的数据集进行标注,以达到至少相同的性能也是非常有意义的。为了解决上述问题,我们设计了一种基于U形深度卷积网络的自动分割方法,并在著名的IBSR 18数据集上获得了良好的结果,对于脑脊液(CSF),灰质(GM)和白质(WM)的平均DSC度量分别为0.8610,0.9131,0.9003。我们使用Bootstrapping算法来选择最有效的训练数据,并且仅使用50%的训练数据就获得了更先进的分割性能。此外,我们提出了一种基于改进的U网的MR脑组织图像的无标记医学数据的提示性标注策略。该方法运算速度快,可用于临床。

英文摘要:

Accurate segmentation of MR brain tissue is a crucial step for diagnosis,surgical planning, and treatment of brain abnormalities. However,it is a time-consuming task to be performed by medical experts. So, automatic and reliable segmentation methods are required. How to choose appropriate training dataset from limited labeled dataset rather than the whole also has great significance in saving training time. In addition, medical data labeled is too rare and expensive to obtain extensively, so choosing appropriate unlabeled dataset instead of all the datasets to annotate, which can attain at least same performance, is also very meaningful. To solve the problem above, we design an automatic segmentation method based on U-shaped deep convolutional network and obtain excellent result with average DSC metric of 0.8610, 0.9131, 0.9003 for Cerebrospinal Fluid (CSF), Gray Matter (GM) and White Matter (WM) respectively on the well-known IBSR18 dataset. We use bootstrapping algorithm for selecting the most effective training data and get more state-of-the-art segmentation performance by using only 50% of training data. Moreover, we propose a strategy of MR brain tissue images' suggestive annotation for unlabeled medical data based on the modified U-net. The proposed method performs fast and can be used in clinical.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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