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arXiv 1802.03212stat.MLcs.LG
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纵向数据的深度聚类

Deep clustering of longitudinal data

Oxford University(牛津大学);Inserm(法国国家健康与医学研究院);Gustave Roussy Institute(古斯塔夫·鲁西研究所);University Paris-Saclay(巴黎-萨克雷大学);University Paris-Sud(巴黎第十一大学);UVSQ(凡尔赛大学)

Louis Falissard, Guy Fagherazzi, Newton Howard, Bruno Falissard

摘要:

深度神经网络是一系列计算模型,它们在图像、语音或文本分析等多个领域中极大地改善了现有技术。这些方法提供了一个框架来对大型数据集中的复杂的非线性交互进行建模,并且自然适合于使用递归神经网络来分析分层数据,例如纵向数据。另一方面,队列研究已成为流行病学研究领域的重要工具。在这样的研究中,随着时间的推移重复测量变量,以允许从业者将它们的时间演变作为轨迹来研究,并且因此作为纵向数据来研究。本文研究了深度学习框架提供的高级建模技术在队列研究提供的纵向数据分析中的应用。研究方法:提出了一种纵向数据集的可视化和聚类方法,并在真实和模拟数据集上与其他广泛使用的方法进行了比较。结果如下:所提出的方法被证明是一致的与先前存在的程序上的简单任务,并优于他们更复杂的任务,如纵向数据集划分成非球形集群。结论:深度人工神经网络可用于在低维流形中可视化纵向数据,这比传统的纵向图更容易解释。因此,从业者应该开始考虑在未来的研究中使用深度人工神经网络来分析他们的纵向数据。

英文摘要:

Deep neural networks are a family of computational models that have led to a dramatical improvement of the state of the art in several domains such as image, voice or text analysis. These methods provide a framework to model complex, non-linear interactions in large datasets, and are naturally suited to the analysis of hierarchical data such as, for instance, longitudinal data with the use of recurrent neural networks. In the other hand, cohort studies have become a tool of importance in the research field of epidemiology. In such studies, variables are measured repeatedly over time, to allow the practitioner to study their temporal evolution as trajectories, and, as such, as longitudinal data. This paper investigates the application of the advanced modelling techniques provided by the deep learning framework in the analysis of the longitudinal data provided by cohort studies. Methods: A method for visualizing and clustering longitudinal dataset is proposed, and compared to other widely used approaches to the problem on both real and simulated datasets. Results: The proposed method is shown to be coherent with the preexisting procedures on simple tasks, and to outperform them on more complex tasks such as the partitioning of longitudinal datasets into non-spherical clusters. Conclusion: Deep artificial neural networks can be used to visualize longitudinal data in a low dimensional manifold that is much simpler to interpret than traditional longitudinal plots are. Consequently, practitioners should start considering the use of deep artificial neural networks for the analysis of their longitudinal data in studies to come.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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