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arXiv 1802.00883physics.soc-phcs.GT
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成本和效益之间的相互作用引发了非平凡的疫苗接种

Interplay between cost and benefits triggers nontrivial vaccination uptake

Benjamin Steinegger, Alessio Cardillo, Paolo De Los Rios, Jesús Gómez-Gardeñes, Alex Arenas

摘要:

遏制传染病传播是科学界的一项重大挑战。只要有可能,接种疫苗是预防传播的最佳方法,因为它最终会使个人免疫。然而,疫苗并不完美,不能保证完全免疫。不完善的免疫接种推动了反疫苗运动的出现,完全改变了对流行病发病率的预测。在这里,我们提出了一个数学上可解的平均场疫苗接种模型来模拟自发采用疫苗对抗流感样疾病,以及预期的流行病发病率。结果与广泛的蒙特卡罗模拟的流行病和疫苗接种的共同进化过程。有趣的是,结果揭示了疫苗接种覆盖率的非单调行为,随着疫苗的不完善而增加,然后减少。从所提出的数学模型的稳定性原理分析和理解这种明显的违反直觉的行为。

英文摘要:

The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total immunization is not guaranteed. Imperfect immunization has driven the emergence of anti-vaccine movements that totally alter the predictions about the epidemic incidence. Here, we propose a mathematically solvable mean-field vaccination model to mimic the spontaneous adoption of vaccines against influenza-like diseases, and the expected epidemic incidence. The results are in agreement with extensive Monte Carlo simulations of the epidemics and vaccination co-evolutionary processes. Interestingly, the results reveal a non-monotonic behavior on the vaccination coverage, that increases with the imperfection of the vaccine and after decreases. This apparent counterintuitive behavior is analyzed and understood from stability principles of the proposed mathematical model.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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