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arXiv 1607.01971cs.CV
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用于大型公共卫生数据库纵向分析的眼底图像叠加

Superimposition of eye fundus images for longitudinal analysis from large public health databases

International Prevention Research Institute(国际预防研究所);Swansea University(斯旺西大学);Diabetic Eye Screening Wales(威尔士糖尿病眼部筛查机构);University of Strathclyde(思克莱德大学)

Guillaume Noyel, Rebecca Thomas, Gavin Bhakta, Andrew Crowder, David Owens, Peter Boyle

摘要:

在本文中,提出了一种方法,用于叠加(即注册)的眼底图像的糖尿病筛查多年的糖尿病视网膜病变的人。该方法是全自动的,并且对相机变化和图像在空间和时间上的颜色变化具有鲁棒性。该过程的所有阶段都被设计用于队列公共卫生数据库的纵向分析,其中视网膜检查大约每年进行一次。该方法依赖于一个模型,纠正两个径向失真和仿射变换的图像对,这是鲁棒的显着点拟合。每个阶段都涉及线性估计,然后是非线性优化。图像变形的模型也是可逆的快速计算。该方法已在(1)模拟蒙太奇和(2)公共健康数据库中进行了验证,其中69名患者具有高质量图像(271对主要使用不同类型的相机采集,268对主要使用相同类型的相机采集),成功率为92%和98%,5名患者(20对)具有低质量图像,成功率为100%。与两种最先进的方法相比,我们的方法得到了更好的结果。

英文摘要:

In this paper, a method is presented for superimposition (i.e. registration) of eye fundus images from persons with diabetes screened over many years for diabetic retinopathy. The method is fully automatic and robust to camera changes and colour variations across the images both in space and time. All the stages of the process are designed for longitudinal analysis of cohort public health databases where retinal examinations are made at approximately yearly intervals. The method relies on a model correcting two radial distortions and an affine transformation between pairs of images which is robustly fitted on salient points. Each stage involves linear estimators followed by non-linear optimisation. The model of image warping is also invertible for fast computation. The method has been validated (1) on a simulated montage and (2) on public health databases with 69 patients with high quality images (271 pairs acquired mostly with different types of camera and 268 pairs acquired mostly with the same type of camera) with success rates of 92% and 98%, and five patients (20 pairs) with low quality images with a success rate of 100%. Compared to two state-of-the-art methods, ours gives better results.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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