预湿毛细管中液塞的动力学:从加速和破裂到减速和气道阻塞
Dynamics of liquid plugs in prewetted capillary tubes: from acceleration and rupture to deceleration and airway obstruction
摘要:
对预湿圆柱形毛细管内恒压头下单个液塞的动力学进行了实验和理论研究。它示出,取决于预湿膜的厚度和压头的大小,塞子可以经历连续的加速,导致其尺寸的急剧减小,并最终破裂,或者相反,与它们的生长和气道阻塞的加剧相关的逐渐减速。这些行为用简单的非线性模型定量再现[Baudoin等人,Proc. Nat. Ac. Sci. USA,2013,110,859],此处适用于圆柱形通道。此外,这两个政权之间的过渡的分析标准的推导和成功地与大量的实验数据进行比较。这项工作对肺阻塞性疾病的潜在影响进行了讨论。
英文摘要:
The dynamics of individual liquid plugs pushed at constant pressure head inside prewetted cylindrical capillary tubes is investigated experimentally and theoretically. It is shown that, depending on the thickness of the prewetting film and the magnitude of the pressure head, the plugs can either experience a continuous acceleration leading to a dramatic decrease of their size and eventually their rupture or conversely, a progressive deceleration associated with their growth and an exacerbation of the airway obstruction. These behaviors are quantitatively reproduced with a simple nonlinear model [Baudoin et al., Proc. Nat. Ac. Sci. USA, 2013, 110, 859] adapted here for cylindrical channels. Furthermore, an analytical criterion for the transition between these two regimes is derived and successfully compared with extensive experimental data. The potential implications of this work for pulmonary obstructive diseases are discussed.
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