Shrinkage estimators have profound impacts in statistics and in scientific and engineering applications. In this article, we consider shrinkage estimation in the presence of linear predictors. We formulate two heteroscedastic hierarchical regression models and study optimal shrinkage estimators in each model. A class of shrinkage estimators, both parametric and semiparametric, based on unbiased risk estimate (URE) is proposed and is shown to be (asymptotically) optimal under mean squared error loss in each model. Simulation study is conducted to compare the performance of the proposed methods with existing shrinkage estimators. We also apply the method to real data and obtain encouraging and interesting results.
Small area estimation has become an important tool in official statistics, used to construct estimates of population quantities for domains with small sample sizes. Typical area-level models function as a type of heteroscedastic regression, where the variance for each domain is assumed to be known and plugged in following a design-based estimate. Recent work has considered hierarchical models for the variance, where the design-based estimates are used as an additional data point to model the latent true variance in each domain. These hierarchical models may incorporate covariate information, b…
The mixture of Dirichlet process (MDP) defines a flexible prior distribution on the space of probability measures. This study shows that ordinary least-squares (OLS) estimator, as a functional of the MDP posterior distribution, has posterior mean given by weighted least-squares (WLS), and has posterior covariance matrix given by the (weighted) heteroscedastic-consistent sandwich estimator. This is according to a pairs bootstrap distribution approximation of the posterior, using a Pólya urn scheme. Also, when the MDP prior baseline distribution is specified as a product of independent probabili…
Constrained approaches to maximum likelihood estimation in the context of finite mixtures of normals have been presented in the literature. A fully data-dependent constrained method for maximum likelihood estimation of clusterwise linear regression is proposed, which extends previous work in equivariant data-driven estimation of finite mixtures of Gaussians for classification. The method imposes plausible bounds on the component variances, based on a target value estimated from the data, which we take to be the homoscedastic variance. Nevertheless, the present work does not only focus on class…
Shrinkage algorithms are of great importance in almost every area of statistics due to the increasing impact of big data. Especially time series analysis benefits from efficient and rapid estimation techniques such as the lasso. However, currently lasso type estimators for autoregressive time series models still focus on models with homoscedastic residuals. Therefore, an iteratively reweighted adaptive lasso algorithm for the estimation of time series models under conditional heteroscedasticity is presented in a high-dimensional setting. The asymptotic behaviour of the resulting estimator is a…
University of Pennsylvania（宾夕法尼亚大学）；Temple University（天普大学）；University of Michigan（密歇根大学）
Large-scale modern data often involves estimation and testing for high-dimensional unknown parameters. It is desirable to identify the sparse signals, ``the needles in the haystack'', with accuracy and false discovery control. However, the unprecedented complexity and heterogeneity in modern data structure require new machine learning tools to effectively exploit commonalities and to robustly adjust for both sparsity and heterogeneity. In addition, estimates for high-dimensional parameters often lack uncertainty quantification. In this paper, we propose a novel Spike-and-Nonparametric mixture …
In many areas of science and engineering, computer simulations are widely used as proxies for physical experiments, which can be infeasible or unethical. Such simulations can often be computationally expensive, and an emulator can be trained to efficiently predict the desired response surface. A widely-used emulator is the Gaussian process (GP), which provides a flexible framework for efficient prediction and uncertainty quantification. Standard GPs, however, do not capture structured sparsity on the underlying response surface, which is present in many applications, particularly in the physic…
We introduce a hierarchical nonparametric model for probability measures based on a multi-resolution transformation of probability distributions. The model allows a varying amount of shrinkage to be applied to data features of different scales and/or at different locations in the sample space, and the varying shrinkage level is locally adaptive to the empirical behavior of the data. Moreover, the model's hierarchical design---through a latent Markov tree structure---allows borrowing of information across locations and scales in setting the adaptive shrinkage level. Inference under the model pr…
This paper focuses on Bayesian shrinkage for covariance matrix estimation. We examine posterior properties and frequentist risks of Bayesian estimators based on new hierarchical inverse-Wishart priors. More precisely, we give the existence conditions of the posterior distributions. Advantages in terms of numerical simulations of posteriors are shown. A simulation study illustrates the performance of the estimation procedures under three loss functions for relevant sample sizes and various covariance structures.
Department of Physics, UC Berkeley（加州大学伯克利分校物理系）；Department of Statistics, UC Berkeley（加州大学伯克利分校统计系）；EECS Department, UC Berkeley（加州大学伯克利分校电机工程与计算机科学系）
Tree-based models such as decision trees and random forests (RF) are a cornerstone of modern machine-learning practice. To mitigate overfitting, trees are typically regularized by a variety of techniques that modify their structure (e.g. pruning). We introduce Hierarchical Shrinkage (HS), a post-hoc algorithm that does not modify the tree structure, and instead regularizes the tree by shrinking the prediction over each node towards the sample means of its ancestors. The amount of shrinkage is controlled by a single regularization parameter and the number of data points in each ancestor. Since …
The graphon (W-graph), including the stochastic block model as a special case, has been widely used in modeling and analyzing network data. This random graph model is well-characterized by its graphon function, and estimation of the graphon function has gained a lot of recent research interests. Most existing works focus on community detection in the latent space of the model, while adopting simple maximum likelihood or Bayesian estimates for the graphon or connectivity parameters given the identified communities. In this work, we propose a hierarchical Binomial model and develop a novel empir…
Meta-analytic methods may be used to combine evidence from different sources of information. Quite commonly, the normal-normal hierarchical model (NNHM) including a random-effect to account for between-study heterogeneity is utilized for such analyses. The same modeling framework may also be used to not only derive a combined estimate, but also to borrow strength for a particular study from another by deriving a shrinkage estimate. For instance, a small-scale randomized controlled trial could be supported by a non-randomized study, e.g. a clinical registry. This would be particularly attractiv…
The negative multinomial distribution is a multivariate generalization of the negative binomial distribution. In this paper, we consider the problem of estimating an unknown matrix of probabilities on the basis of observations of negative multinomial variables under the standardized squared error loss. First, a general sufficient condition for a shrinkage estimator to dominate the UMVU estimator is derived and an empirical Bayes estimator satisfying the condition is constructed. Next, a hierarchical shrinkage prior is introduced, an associated Bayes estimator is shown to dominate the UMVU esti…
In this paper, we treat estimation and prediction problems where negative multinomial variables are observed and in particular consider unbalanced settings. First, the problem of estimating multiple negative multinomial parameter vectors under the standardized squared error loss is treated and a new empirical Bayes estimator which dominates the UMVU estimator under suitable conditions is derived. Second, we consider estimation of the joint predictive density of several multinomial tables under the Kullback-Leibler divergence and obtain a sufficient condition under which the Bayesian predictive…
We have developed a sophisticated statistical model for predicting the hitting performance of Major League baseball players. The Bayesian paradigm provides a principled method for balancing past performance with crucial covariates, such as player age and position. We share information across time and across players by using mixture distributions to control shrinkage for improved accuracy. We compare the performance of our model to current sabermetric methods on a held-out season (2006), and discuss both successes and limitations.
A novel extrapolation method is proposed for longitudinal forecasting. A hierarchical Gaussian process model is used to combine nonlinear population change and individual memory of the past to make prediction. The prediction error is minimized through the hierarchical design. The method is further extended to joint modeling of continuous measurements and survival events. The baseline hazard, covariate and joint effects are conveniently modeled in this hierarchical structure. The estimation and inference are implemented in fully Bayesian framework using the objective and shrinkage priors. In si…
Tissue-agnostic trials enroll patients based on their genetic biomarkers, not tumor type, in an attempt to determine if a new drug can successfully treat disease conditions based on biomarkers. The Bayesian hierarchical model (BHM) provides an attractive approach to design phase II tissue-agnostic trials by allowing information borrowing across multiple disease types. In this article, we elucidate two intrinsic and inevitable issues that may limit the use of BHM to tissue-agnostic trials: sensitivity to the prior specification of the shrinkage parameter and the competing "interest" among disea…
For small area estimation of area-level data, the Fay-Herriot model is extensively used as a model based method. In the Fay-Herriot model, it is conventionally assumed that the sampling variances are known whereas estimators of sampling variances are used in practice. Thus, the settings of knowing sampling variances are unrealistic and several methods are proposed to overcome this problem. In this paper, we assume the situation where the direct estimators of the sampling variances are available as well as the sample means. Using these information, we propose a Bayesian yet objective method pro…
Demanding sparsity in estimated models has become a routine practice in statistics. In many situations, we wish to require that the sparsity patterns attained honor certain problem-specific constraints. Hierarchical sparse modeling (HSM) refers to situations in which these constraints specify that one set of parameters be set to zero whenever another is set to zero. In recent years, numerous papers have developed convex regularizers for this form of sparsity structure, which arises in many areas of statistics including interaction modeling, time series analysis, and covariance estimation. In t…
DTVEM-RE: A Hierarchical Random-Effects Extension of the Differential Time-Varying Effect Model for Person-Specific Multi-Lag Estimation in Intensive Longitudinal Data
Geisel School of Medicine, Dartmouth College（达特茅斯学院盖泽尔医学院）
The two-level normal hierarchical model (NHM) has played a critical role in the theory of small area estimation (SAE), one of the growing areas in statistics with numerous applications in different disciplines. In this paper, we address major well-known shortcomings associated with the empirical best linear unbiased prediction (EBLUP) of a small area mean and its mean squared error (MSE) estimation by considering an appropriate model variance estimator that satisfies multiple properties. The proposed model variance estimator simultaneously (i) improves on the estimation of the related shrinkag…
