非洲南部和东部的古代西欧亚血统
Ancient west Eurasian ancestry in southern and eastern Africa
摘要:
南部非洲的历史涉及土著狩猎采集者和进入该地区的一系列人口之间的互动。在这里,我们使用全基因组遗传数据表明,在科伊桑人的历史上至少有两个混合事件(南部非洲狩猎采集者和牧民谁说非班图语的点击辅音)。一个涉及与讲刚果语的非洲人口有关的人口,另一个介绍了与欧亚西部(欧洲或中东)人口最密切相关的祖先。我们将后一次混合事件的时间定在大约900- 1800年前,并表明它对讲Khoe-Kwadi语言的科伊桑人的人口影响最大。类似的欧亚西部血统的信号在整个东非都存在。特别是,我们还发现了肯尼亚、坦桑尼亚和埃塞俄比亚人口历史上两次混合事件的证据,其中较早的一次涉及与欧亚大陆西部有关的人口,我们可以追溯到大约2,700 - 3,300年前。我们重建的等位基因频率的假定西欧亚人口在非洲东部,并表明,这个人口是一个很好的代理西欧亚血统在非洲南部。对这些发现最简单的解释是,欧亚西部的祖先通过东非间接进入南部非洲。
英文摘要:
The history of southern Africa involved interactions between indigenous hunter-gatherers and a range of populations that moved into the region. Here we use genome-wide genetic data to show that there are at least two admixture events in the history of Khoisan populations (southern African hunter-gatherers and pastoralists who speak non-Bantu languages with click consonants). One involved populations related to Niger-Congo-speaking African populations, and the other introduced ancestry most closely related to west Eurasian (European or Middle Eastern) populations. We date this latter admixture event to approximately 900-1,800 years ago, and show that it had the largest demographic impact in Khoisan populations that speak Khoe-Kwadi languages. A similar signal of west Eurasian ancestry is present throughout eastern Africa. In particular, we also find evidence for two admixture events in the history of Kenyan, Tanzanian, and Ethiopian populations, the earlier of which involved populations related to west Eurasians and which we date to approximately 2,700 - 3,300 years ago. We reconstruct the allele frequencies of the putative west Eurasian population in eastern Africa, and show that this population is a good proxy for the west Eurasian ancestry in southern Africa. The most parsimonious explanation for these findings is that west Eurasian ancestry entered southern Africa indirectly through eastern Africa.
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