血液和其他多组分悬浮液受限流动中的边集机理
Mechanism of margination in confined flows of blood and other multicomponent suspensions
摘要:
流动的血液显示出一种称为边缘化的现象,其中白细胞和血小板优先在血管壁附近发现,而红细胞从这些区域耗尽。在这里边际研究使用直接流体动力学模拟的二元悬浮液的硬(S)和软(F)胶囊,以及一个随机模型,该模型结合了悬浮液中的关键粒子传输机制-壁诱导的流体动力学迁移和剪切诱导的对碰撞。随机模型允许直接评估这两种机制的相对重要性,从而表明边缘化(至少在稀释情况下)很大程度上是由于均相(例如s-s)和非均相(s-f)碰撞的微分动力学造成的
英文摘要:
Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct hydrodynamic simulations of a binary suspension of stiff (s) and floppy (f) capsules, as well as a stochastic model that incorporates the key particle transport mechanisms in suspensions -- wall-induced hydrodynamic migration and shear-induced pair collisions. The stochastic model allows the relative importance of these two mechanisms to be directly evaluated and thereby indicates that margination, at least in the dilute case, is largely due to the differential dynamics of homogeneous (e.g. s-s) and heterogeneous (s-f) collisions
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