The research work presented in this paper is to achieve the tissue classification and automatically diagnosis the abnormal tumor region present in Computed Tomography (CT) images using the wavelet based statistical texture analysis method. Comparative studies of texture analysis method are performed for the proposed wavelet based texture analysis method and Spatial Gray Level Dependence Method (SGLDM). Our proposed system consists of four phases i) Discrete Wavelet Decomposition (ii) Feature extraction (iii) Feature selection (iv) Analysis of extracted texture features by classifier. A wavelet based statistical texture feature set is derived from normal and tumor regions. Genetic Algorithm (GA) is used to select the optimal texture features from the set of extracted texture features. We construct the Support Vector Machine (SVM) based classifier and evaluate the performance of classifier by comparing the classification results of the SVM based classifier with the Back Propagation Neural network classifier(BPN). The results of Support Vector Machine (SVM), BPN classifiers for the texture analysis methods are evaluated using Receiver Operating Characteristic (ROC) analysis. Experimental results show that the classification accuracy of SVM is 96% for 10 fold cross validation method. The system has been tested with a number of real Computed Tomography brain images and has achieved satisfactory results.
Learning Global and Local Features of Normal Brain Anatomy for Unsupervised Abnormality Detection
National Cancer Center Research Institute（国家癌症中心研究所）；RIKEN Center for Advanced Intelligence Project（理化学研究所先进智能项目中心）；Graduate School of Information Science and Technology, The University of Tokyo（东京大学信息科学与技术研究生院）；Research Center for Advanced Science and Technology, The University of Tokyo（东京大学先进科学技术研究中心）；National Cancer Center Hospital（国家癌症中心医院）
Adaptive Local Binary Pattern: A Novel Feature Descriptor for Enhanced Analysis of Kidney Abnormalities in CT Scan Images using ensemble based Machine Learning Approach
Indian Statistical Institute（印度统计研究所）；DAV Institute of Engineering and Technology（DAV工程技术学院）
Inspired by the success of Convolutional Neural Networks (CNN), we develop a novel Computer Aided Detection (CADe) system using CNN for Glioblastoma Multiforme (GBM) detection and segmentation from multi channel MRI data. A two-stage approach first identifies the presence of GBM. This is followed by a GBM localization in each "abnormal" MR slice. As part of the CADe system, two CNN architectures viz. Classification CNN (C-CNN) and Detection CNN (D-CNN) are employed. The CADe system considers MRI data consisting of four sequences ($T_1$, $T_{1c},$ $T_2$, and $T_{2FLAIR}$) as input, and automati…
One of the most important tasks in medical image processing is the brain's whole tumor segmentation. It assists in quicker clinical assessment and early detection of brain tumors, which is crucial for lifesaving treatment procedures of patients. Because, brain tumors often can be malignant or benign, if they are detected at an early stage. A brain tumor is a collection or a mass of abnormal cells in the brain. The human skull encloses the brain very rigidly and any growth inside this restricted place can cause severe health issues. The detection of brain tumors requires careful and intricate a…
The Johns Hopkins University（约翰斯·霍普金斯大学）；The Johns Hopkins University School of Medicine（约翰斯·霍普金斯大学医学院）
Automatic abnormality detection in abdominal CT scans can help doctors improve the accuracy and efficiency in diagnosis. In this paper we aim at detecting pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic cancer. Taking the fact that the existence of tumor can affect both the shape and the texture of pancreas, we design a system to extract the shape and texture feature at the same time for detecting PDAC. In this paper we propose a two-stage method for this 3D classification task. First, we segment the pancreas into a binary mask. Second, a FusionNet is proposed to take both …
Brain Tumor Classification from MRI Scans via Transfer Learning and Enhanced Feature Representation
Department of CSE, Netrokona University（计算机科学与工程系，Netrokona大学）；Department of CSE, The University of Rajshahi（计算机科学与工程系，拉贾沙希大学）；Department of Information Technology, Allen E. Paulson College of Engineering and Computing, Georgia Southern University（信息技术系，乔治亚南方大学）；Centre for Image and Vision Computing (CIVC), COE for Artificial Intelligence, Faculty of Artificial Intelligence and Engineering (FAIE), Multimedia University（图像与视觉计算中心（CIVC），人工智能学院，人工智能与工程学院，多媒体大学）
Institute of Computing Technology, Chinese Academy of Sciences（中国科学院计算技术研究所）；University of Chinese Academy of Sciences（中国科学院大学）；University of California, Los Angeles（加利福尼亚大学洛杉矶分校）；University of Southern California（南加利福尼亚大学）；Lenovo Research（联想研究院）；Lenovo Ltd.（联想有限公司）
Purpose: Automated liver tumor segmentation from Computed Tomography (CT) images is a necessary prerequisite in the interventions of hepatic abnormalities and surgery planning. However, accurate liver tumor segmentation remains challenging due to the large variability of tumor sizes and inhomogeneous texture. Recent advances based on Fully Convolutional Network (FCN) for medical image segmentation drew on the success of learning discriminative pyramid features. In this paper, we propose a Decoupled Pyramid Correlation Network (DPC-Net) that exploits attention mechanisms to fully leverage both …
École de Technologie Supérieure, Université du Québec（魁北克大学高等技术学院）
Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to assist the specialist in interpreting the breast digital image exam, providing features for detecting and diagnosing tumors and cancerous cells. Nonetheless, detecting tumors with a high sensitivity rate and reducing the false positives rate is still challenging. Texture descriptors have been quite popular in medical image analysis, particularly in histopath…
To deform or not: treatment-aware longitudinal registration for breast DCE-MRI during neoadjuvant chemotherapy via unsupervised keypoints detection
Radboud University Medical Centre（拉德堡德大学医学中心）；The Netherlands Cancer Institute（荷兰癌症研究所）；Macao Polytechnic University（澳门理工大学）；Maastricht University Medical Centre（马斯特里赫特大学医学中心）
JIS College of Engineering（JIS工程学院）；Kalyani Govt. Engineering College（卡利亚尼政府工程学院）；Jadavpur University（贾达普大学）
The present work proposes a computer-aided normal and abnormal heart sound identification based on Discrete Wavelet Transform (DWT), it being useful for tele-diagnosis of heart diseases. Due to the presence of Cumulative Frequency components in the spectrogram, DWT is applied on the spectro-gram up to n level to extract the features from the individual approximation components. One dimensional feature vector is obtained by evaluating the Row Mean of the approximation components of these spectrograms. For this present approach, the set of spectrograms has been considered as the database, rather…
University of Dhaka（达卡大学）；National Institute of Neuroscience and Hospital（国家神经科学研究所及医院）
Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find abnormalities in soft tissues. Traditionally they are analyzed by a radiologist to detect abnormalities in soft tissues, especially the brain. The process of interpreting a massive volume of patient's MRI is laborious. Hence, the use of Machine Learning methodologies can aid in detecting abnormalities in soft tissues with considerable accuracy. In this research, we hav…
Comparative Evaluation of Transfer Learning for Classification of Brain Tumor Using MRI
Florida Institute of Technology（佛罗里达理工学院）；Daffodil International University（达福德国际大学）；University of North Texas（北德克萨斯大学）；The University of Alabama at Birmingham（阿拉巴马大学伯明翰分校）
Brain tumors are masses or abnormal growths of cells within the brain or the central spinal canal with symptoms such as headaches, seizures, weakness or numbness in the arms or legs, changes in personality or behaviour, nausea, vomiting, vision or hearing problems and dizziness. Conventional diagnosis of brain tumour involves some tests and procedure which may include the consideration of medical history, physical examination, imaging tests (such as CT or MRI scans), and biopsy (removal and examination of a small piece of the tumor tissue). These procedures, while effective, are mentally stren…
University of Sydney（悉尼大学）；Royal Prince Alfred Hospital（阿尔弗雷德王子医院）
The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization from CT. Current methods for PET-CT image analysis either process the modalities separately or fuse information from each modality based on knowledge about the image analysis task. These methods generally do not consider the spatially varying visual characteristics that encode different information across the different modalities, which have different priori…
Cardiovascular system study using ECG signals have evolved tremendously in the domain of electronics and signal processing. However, there are certain floating challenges unresolved in the analysis and detection of abnormal performances of cardiovascular system. As the medical field is moving towards more automated and intelligent systems, wrong detection or wrong interpretations of ECG waveform of abnormal conditions can be quite fatal. Since the PQRST signals vary their positions randomly, the process of locating, identifying and classifying each feature can be cumbersome and it is prone to …
University of Georgia（佐治亚大学）；Zhongnan Hospital of Wuhan University（武汉大学中南医院）；Shanghai Jiao Tong University（上海交通大学）
In this paper we consider the problem of unsupervised anomaly segmentation in medical images, which has attracted increasing attention in recent years due to the expensive pixel-level annotations from experts and the existence of a large amount of unannotated normal and abnormal image scans. We introduce a segmentation network that utilizes adversarial learning to partition an image into two cuts, with one of them falling into a reference distribution provided by the user. This Adversarial-based Selective Cutting network (ASC-Net) bridges the two domains of cluster-based deep segmentation and …
Detection and segmentation of Brain tumor is very important because it provides anatomical information of normal and abnormal tissues which helps in treatment planning and patient follow-up. There are number of techniques for image segmentation. Proposed research work uses ANFIS (Artificial Neural Network Fuzzy Inference System) for image classification and then compares the results with FCM (Fuzzy C means) and K-NN (K-nearest neighbor). ANFIS includes benefits of both ANN and the fuzzy logic systems. A comprehensive feature set and fuzzy rules are selected to classify an abnormal image to the…
With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful energy when diagnosing brain abnormalities. Aiming at the imbalance of brain tumor data and the rare amount of labeled data, we propose an innovative brain tumor abnormality detection algorithm. The semi-supervised anomaly detection model is proposed in which only healthy (normal) brain images are trained. Model capture the common pattern of the normal images …
A generalizable large-scale foundation model for musculoskeletal radiographs
Seoul National University Hospital（首尔大学医院）；Seoul National University（首尔大学）；Seoul National University College of Medicine（首尔大学医学院）；Seoul National University Bundang Hospital（首尔大学盆唐医院）
Automated MRI Tumor Segmentation using hybrid U-Net with Transformer and Efficient Attention
Department of Medical Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS)（医学系，巴基斯坦工程与应用科学研究所）；Pakistan Institute of Engineering and Applied Sciences (PIEAS)（巴基斯坦工程与应用科学研究所）；Department of Physics & Applied Mathematics, Pakistan Institute of Engineering and Applied Sciences (PIEAS)（物理与应用数学系，巴基斯坦工程与应用科学研究所）；Center for Mathematical Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS)（数学科学中心，巴基斯坦工程与应用科学研究所）；Pattern Recognition Lab, Department of Computer & Information Sciences, Pakistan Institute of Engineering & Applied Sciences（模式识别实验室，计算机与信息科学系，巴基斯坦工程与应用科学研究所）；Pakistan Institute of Engineering & Applied Sciences（巴基斯坦工程与应用科学研究所）；Artificial Intelligence Center (PAIC), Pakistan Institute of Engineering & Applied Sciences（人工智能中心（PAIC），巴基斯坦工程与应用科学研究所）
Unsupervised Patch-GAN with Targeted Patch Ranking for Fine-Grained Novelty Detection in Medical Imaging
the Southern University of Science and Technology（南方科技大学）；University of Oxford（牛津大学）；Tsinghua University（清华大学）；University of Warwick（华威大学）；Northwest University（西北大学）；Peng Cheng Lab（鹏城实验室）
Targeted Neural Architectures in Multi-Objective Frameworks for Complete Glioma Characterization from Multimodal MRI
School of Computer Science and Engineering, Vellore Institute of Technology（韦洛尔理工学院计算机科学与工程学院）；College of Engineering, Guindy, Anna University（安娜大学金迪工程学院）；Institute of Neurosurgery, Madras Medical College（马德拉斯医学院神经外科研究所）
Breast cancer is in the most common malignant tumor in women. It accounted for 30% of new malignant tumor cases. Although the incidence of breast cancer remains high around the world, the mortality rate has been continuously reduced. This is mainly due to recent developments in molecular biology technology and improved level of comprehensive diagnosis and standard treatment. Early detection by mammography is an integral part of that. The most common breast abnormalities that may indicate breast cancer are masses and calcifications. Previous detection approaches usually obtain relatively high s…
The University of Buckingham（白金汉大学）；Salahaddin University（萨拉赫丁大学）
An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this work we build more than one PD representation of a single image based on a landmark selection method, known as local binary patterns, that encode different types of local textures from images. We employed different PD vectorizations using persistence landscapes, persistence images, persistence binning (Betti Curve) and statistics. We tested the effectiveness…
A Two-Stage Generative Model with CycleGAN and Joint Diffusion for MRI-based Brain Tumor Detection
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；University of Chinese Academy of Sciences（中国科学院大学）；Peking University Shenzhen Hospital（北京大学深圳医院）；National Center for Applied Mathematics Shenzhen（深圳国家应用数学中心）
Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and accurate enough to process a large amount of data and it often leads to bias. To resolve this problem, we attempted to create an automatic image classifier using Machine Learning to locate human proteins with higher speed and accuracy than human beings. We implemented a Convolution Neural Network with Residue and Squeeze-Excitation layers classifier to locate gi…
Capsule Endoscopy Multi-classification via Gated Attention and Wavelet Transformations
National Institute of Technology Puducherry（本地治里国家技术学院）；Sardar Vallabhbhai National Institute of Technology Surat（苏拉特萨达尔·瓦拉巴伊国家技术学院）；Norwegian University of Science and Technology（挪威科技大学）
Indian Institute of Technology, Delhi（印度理工学院德里分校）；Indian Institute of Technology, Guwahati（印度理工学院古瓦哈提分校）；Fortis memorial research institute（富通纪念研究院）
The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and disorders and plays a major role in clinical neuro-diagnosis. Supplementing this technique with automated classification and segmentation tools is gaining importance, to reduce errors and time needed to make a conclusive diagnosis. In this paper a simple three-step algorithm is proposed; (1) identification of patients that present with tumors, (2) automatic selecti…
National Institute of Technology Raipur（印度国立技术学院赖布尔分校）
Brain Tumors are abnormal mass of clustered cells penetrating regions of brain. Their timely identification and classification help doctors to provide appropriate treatment. However, Classifi-cation of Brain Tumors is quite intricate because of high-intra class similarity and low-inter class variability. Due to morphological similarity amongst various MRI-Slices of different classes the challenge deepens more. This all leads to hampering generalizability of classification models. To this end, this paper proposes HSADML, a novel framework which enables deep metric learning (DML) using SphereFac…
To improve patient survival and treatment outcomes, early diagnosis of brain tumors is an essential task. It is a difficult task to evaluate the magnetic resonance imaging (MRI) images manually. Thus, there is a need for digital methods for tumor diagnosis with better accuracy. However, it is still a very challenging task in assessing their shape, volume, boundaries, tumor detection, size, segmentation, and classification. In this proposed work, we propose a hybrid ensemble method using Random Forest (RF), K-Nearest Neighbour, and Decision Tree (DT) (KNN-RF-DT) based on Majority Voting Method.…
Generalizable and Explainable Deep Learning for Medical Image Computing: An Overview
School of Artificial Intelligence, Guilin University of Electronic Technology（桂林电子科技大学人工智能学院）；École de Technologie Supérieure (ETS)（高等技术学院）；College of Computer Science and Engineering, Taibah University（塔伊布大学计算机科学与工程学院）；College of Computer Science and Engineering, Jeddah University（吉达大学计算机科学与工程学院）
Clear cell renal cell carcinoma (ccRCC) is one of the most common forms of intratumoral heterogeneity in the study of renal cancer. ccRCC originates from the epithelial lining of proximal convoluted renal tubules. These cells undergo abnormal mutations in the presence of Ki67 protein and create a lump-like structure through cell proliferation. Manual counting of tumor cells in the tissue-affected sections is one of the strongest prognostic markers for renal cancer. However, this procedure is time-consuming and also prone to subjectivity. These assessments are based on the physical cell appeara…
Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle anatomical variability, Unsupervised Anomaly Detection (UAD) methods are proposed, detecting anomalies as outliers of a healthy model learned using a Variational Autoencoder (VAE). Previous work on UAD adopted a 2D approach, meaning that MRIs are processed as a collection of independent slices. Yet, it does not fully exploit the spatial information contained in …
SRM Institute of Science and Technology（SRM科学技术研究所）
Abnormal development of tissues in the body as a result of swelling and morbid enlargement is known as a tumor. They are mainly classified as Benign and Malignant. Tumour in the brain is fatal as it may be cancerous, so it can feed on healthy cells nearby and keep increasing in size. This may affect the soft tissues, nerve cells, and small blood vessels in the brain. Hence there is a need to detect and classify them during the early stages with utmost precision. There are different sizes and locations of brain tumors which makes it difficult to understand their nature. The process of detection…
BUET（孟加拉国工程技术大学）；United International University（联合国际大学）
Lung cancer is a leading cause of death in most countries of the world. Since prompt diagnosis of tumors can allow oncologists to discern their nature, type and the mode of treatment, tumor detection and segmentation from CT Scan images is a crucial field of study worldwide. This paper approaches lung tumor segmentation by applying two-dimensional discrete wavelet transform (DWT) on the LOTUS dataset for more meticulous texture analysis whilst integrating information from neighboring CT slices before feeding them to a Deeply Supervised MultiResUNet model. Variations in learning rates, decay an…
A supervised diagnosis system for digital mammogram is developed. The diagnosis processes are done by transforming the data of the images into a feature vector using wavelets multilevel decomposition. This vector is used as the feature tailored toward separating different mammogram classes. The suggested model consists of artificial neural networks designed for classifying mammograms according to tumor type and risk level. Results are enhanced from our previous study by extracting feature vectors using multilevel decompositions instead of one level of decomposition. Radiologist-labeled images …
HiFi-Syn: Hierarchical Granularity Discrimination for High-Fidelity Synthesis of MR Images with Structure Preservation
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院附属瑞金医院）；College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院健康科学技术学院）；Clinical Neuroscience Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院附属瑞金医院临床神经科学中心）；National Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy, Shanghai Jiao Tong University（上海交通大学先进磁共振诊断与治疗技术国家工程研究中心）；Ping An Technology (Shenzhen) Co., Ltd.（平安科技（深圳）有限公司）
Brain cancer can be very fatal, but chances of survival increase through early detection and treatment. Doctors use Magnetic Resonance Imaging (MRI) to detect and locate tumors in the brain, and very carefully analyze scans to segment brain tumors. Manual segmentation is time consuming and tiring for doctors, and it can be difficult for them to notice extremely small abnormalities. Automated segmentations performed by computers offer quicker diagnoses, the ability to notice small details, and more accurate segmentations. Advances in deep learning and computer hardware have allowed for high-per…
