蛋白质家族同源性的标度性质
Scaling properties of protein family phylogenies
摘要：
进化生物学中的一个经典问题是进化过程如何在基因和物种水平上耦合。出于这个动机，我们比较的拓扑性质（主要是深度缩放，作为一个表征的平衡）的一个大的一组蛋白质类的一组物种的类。比较分析表明，这两套的生物多样性共享显着相似的缩放行为，表明分支规则和进化过程的普遍性，推动生物多样性从基因到物种水平。为了解释这种普遍性，我们提出了一个简单的模型，使我们能够估计的比例的进化性/鲁棒性所需的近似的缩放行为中观察到的遗传，突出的相关性的鲁棒性的生物系统（物种或蛋白质）的缩放特性的系统发育树。因此，决定生物系统不能多样化的规则在基因和物种水平上都是同样相关的。
英文摘要：
One of the classical questions in evolutionary biology is how evolutionary processes are coupled at the gene and species level. With this motivation, we compare the topological properties (mainly the depth scaling, as a characterization of balance) of a large set of protein phylogenies with a set of species phylogenies. The comparative analysis shows that both sets of phylogenies share remarkably similar scaling behavior, suggesting the universality of branching rules and of the evolutionary processes that drive biological diversification from gene to species level. In order to explain such generality, we propose a simple model which allows us to estimate the proportion of evolvability/robustness needed to approximate the scaling behavior observed in the phylogenies, highlighting the relevance of the robustness of a biological system (species or protein) in the scaling properties of the phylogenetic trees. Thus, the rules that govern the incapability of a biological system to diversify are equally relevant both at the gene and at the species level.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
