脂质颗粒在体内的异常扩散和弱遍历性破缺
In vivo anomalous diffusion and weak ergodicity breaking of lipid granules
摘要：
结合广泛的单粒子跟踪显微镜数据的内源性脂质颗粒在活的裂变酵母细胞的分析结果，我们发现的证据异常扩散和弱遍历性打破。也就是说，我们证明，在短时间内的颗粒进行subdiffusion根据法律的连续时间随机游走理论。相关联的违反遍历性导致的特征营业额之间的时间平均均方位移的两个标度制度。在较长的时间，颗粒运动是一致的分数布朗运动。
英文摘要：
Combining extensive single particle tracking microscopy data of endogenous lipid granules in living fission yeast cells with analytical results we show evidence for anomalous diffusion and weak ergodicity breaking. Namely we demonstrate that at short times the granules perform subdiffusion according to the laws of continuous time random walk theory. The associated violation of ergodicity leads to a characteristic turnover between two scaling regimes of the time averaged mean squared displacement. At longer times the granule motion is consistent with fractional Brownian motion.
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