离子辐照与生物分子辐射损伤II。间接影响
Ion irradiation and biomolecular radiation damage II. Indirect effect
摘要：
据报道，电离辐射对活细胞基因组的损伤约有三分之一是直接的，三分之二是间接的。前者已在我们的上一篇论文中介绍，涉及直接的能量沉积和电离反应的生物分子;后者的结果从辐射诱导的活性物种（主要是自由基）在介质（主要是水）周围的生物分子。本文综述了离子注入在水中引起自由基形成的研究进展。然后对DNA、蛋白质及其组分的水溶液自由基反应化学进行了综述，并对二次粒子（离子和电子）引起的生物分子损伤作了简要介绍。还讨论了一些下游生物效应。
英文摘要：
It has been reported that damage of genome in a living cell by ionizing radiation is about one-third direct and two-thirds indirect. The former which has been introduced in our last paper, concerns direct energy deposition and ionizing reactions in the biomolecules; the latter results from radiation induced reactive species (mainly radicals) in the medium (mainly water) surrounding the biomolecules. In this review, a short description of ion implantation induced radical formation in water is presented. Then we summarize the aqueous radical reaction chemistry of DNA, protein and their components, followed by a brief introduction of biomolecular damage induced by secondary particles (ions and electron). Some downstream biological effects are also discussed.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
