聚乳酸-羟基乙酸共聚物厚泡沫组织支架中声传播的初步研究
A preliminary study of acoustic propagation in thick foam tissue scaffolds composed of poly(lactic-co-glycolic acid)
摘要：
声波探测泡沫的结构、机械和流体性质的独特能力可能为组织工程中使用的多孔支架的生物降解提供新的方法。受此启发，我们进行了一个典型的生物聚合物的声学特性和泡沫支架内的声学传播的可行性的初步调查。聚焦于聚（乳酸-羟基乙酸），我们使用脉冲回波方法来确定的纵向声速，其温度依赖性揭示了聚合物的玻璃化转变。最后，我们展示了第一个地形和断层声图像的聚合物泡沫组织支架。
英文摘要：
The exclusive ability of acoustic waves to probe the structural, mechanical and fluidic properties of foams may offer novel approaches to characterise the porous scaffolds employed in tissue engineering. Motivated by this we conduct a preliminary investigation into the acoustic properties of a typical biopolymer and the feasibility of acoustic propagation within a foam scaffold thereof. Focussing on poly(lactic-co-glycolic acid), we use a pulse-echo method to determine the longitudinal speed of sound, whose temperature-dependence reveals the glass transition of the polymer. Finally, we demonstrate the first topographic and tomographic acoustic images of polymer foam tissue scaffolds.
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