arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1002.0065q-bio.BMq-bio.GN
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自动化的DNA基序发现

Automated DNA Motif Discovery

W. B. Langdon, Olivia Sanchez Graillet, A. P. Harrison

摘要:

Ensembl的人类非编码和蛋白质编码基因用于自动查找DNA模式基序。遗传编程使用正则表达式(RE)的巴科斯-诺尔形式(BNF)语法来确保生成的字符串是合法的。进化的基序表明,在转录物早期存在胸腺嘧啶,随后是一个或多个腺嘌呤等,表明非蛋白质编码基因。保留字:假基因、短和微小RNA、非编码转录物、系统生物学、机器学习、生物信息学、模体、正则表达式、强类型遗传编程、上下文无关语法。

英文摘要:

Ensembl's human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal. The evolved motif suggests the presence of Thymine followed by one or more Adenines etc. early in transcripts indicate a non-protein coding gene. Keywords: pseudogene, short and microRNAs, non-coding transcripts, systems biology, machine learning, Bioinformatics, motif, regular expression, strongly typed genetic programming, context-free grammar.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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