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arXiv 0912.4760q-bio.NCphysics.bio-phq-bio.QM
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从模式到运动的行为C。elegans

From modes to movement in the behavior of C. elegans

Greg J Stephens, Bethany Johnson-Kerner, William Bialek, William S Ryu

发表信息：
PLoS ONE 5(11): e13914 (2010)
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摘要：

生物通过改变它们的形状在世界上移动，在这里，我们探索了从形状空间到线虫C运动的映射。当它在平面琼脂表面上爬行时，我们通过方向角速度，方向角和均方位移的相关函数的轨迹的统计特征，我们发现，方向记忆的损失有显着的贡献，从两个突然的，大幅度的转折事件和这些事件之间的连续动态。此外，我们证明了长时间的持久性的方向记忆在突然转弯之间的间隔。最近的工作表明，C。elegans的运动被限制在一个低维的形状空间，我们构建了一个地图，从这个形状空间的动态的蠕虫沿琼脂的轨迹。我们使用这种连接来说明，在连续的动态变化揭示运动策略中发生的两类多巴胺受体缺陷突变体之间的微妙差异。

英文摘要：

Organisms move through the world by changing their shape, and here we explore the mapping from shape space to movements in the nematode C. elegans as it crawls on a planar agar surface. We characterize the statistics of the trajectories through the correlation functions of the orientation angular velocity, orientation angle and the mean-squared displacement, and we find that the loss of orientational memory has significant contributions from both abrupt, large amplitude turning events and the continuous dynamics between these events. Further, we demonstrate long-time persistence of orientational memory in the intervals between abrupt turns. Building on recent work demonstrating that C. elegans movements are restricted to a low-dimensional shape space, we construct a map from the dynamics in this shape space to the trajectory of the worm along the agar. We use this connection to illustrate that changes in the continuous dynamics reveal subtle differences in movement strategy that occur among mutants defective in two classes of dopamine receptors.

机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。

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