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arXiv 0910.3082q-bio.PE
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系统发生网络不需要复杂:使用更少的网格来表示聚类

Phylogenetic Networks Do not Need to Be Complex: Using Fewer Reticulations to Represent Conflicting Clusters

Leo van Iersel, Steven Kelk, Regula Rupp, Daniel Huson

摘要:

系统发育树被广泛用于显示物种群体如何进化的估计。每一棵系统发育树都可以被看作是一个簇的集合,这些簇是从一个共同祖先进化而来的物种的亚群。当针对多个数据集(例如针对不同的基因)获得系统发育树时,它们的聚类通常是矛盾的。因此,这种数据集的所有聚类的集合不能被组合成单个系统发育树。系统发生网络是系统发育树的推广,可用于显示更复杂的进化历史,包括杂交、重组和水平基因转移等网状事件。在这里,我们提出了新的CASS算法,可以将任何一组聚类组合成一个系统发育网络。我们表明,CASS构造的网络通常比其他可用的方法构造的网络简单。此外,我们表明,CASS是保证产生一个网络,最多有两个双连通组件,每当这样的网络存在。我们已经实现了CASS,并将其集成到免费提供的Dendroscope软件中。

英文摘要:

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees are obtained for several data sets (e.g. for different genes), then their clusters are often contradicting. Consequently, the set of all clusters of such a data set cannot be combined into a single phylogenetic tree. Phylogenetic networks are a generalization of phylogenetic trees that can be used to display more complex evolutionary histories, including reticulate events such as hybridizations, recombinations and horizontal gene transfers. Here we present the new CASS algorithm that can combine any set of clusters into a phylogenetic network. We show that the networks constructed by CASS are usually simpler than networks constructed by other available methods. Moreover, we show that CASS is guaranteed to produce a network with at most two reticulations per biconnected component, whenever such a network exists. We have implemented CASS and integrated it in the freely available Dendroscope software.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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