稀有密码子的聚类及其对翻译的影响
On the clustering of rare codons and its effect on translation
摘要：
已知稀有密码子簇的存在会对蛋白质生产的效率和准确性产生负面影响。在本文中，我们展示了一种统计方法，确定这样的集群的编码序列的基因。使用大肠大肠杆菌作为我们的模式生物，我们表明，具有密集簇的基因往往具有较低的蛋白质产量。
英文摘要：
The presence of clusters of rare codons is known to negatively impact the efficiency and accuracy of protein production. In this paper, we demonstrate a statistical method of identifying such clusters in the coding sequence of a gene. Using E. coli as our model organism, we show that genes having denser clusters tend to have lower protein yields.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
