arXivDaily arXiv每日学术速递 周一至周五更新
北美退伍军人节(Veterans Day),12 日无更新
arXiv 0909.3502cond-mat.softq-bio.BM
收藏

二维拉伸具有自发曲率的弱弯曲细丝

Stretching weakly bending filaments with spontaneous curvature in two dimensions

Panayotis Benetatos, Eugene M. Terentjev

摘要:

一些重要的生物分子(例如,细菌FtsZ和真核生物DNA)已知会抑制自发(固有)曲率。使用一个简单的扩展蠕虫状链模型,我们研究了一个弱弯曲的细丝在两个维度上施加在其两端的拉力的响应(一种常见的配置在经典的体外实验和相关的几个体内细胞的情况下)。这种链或细丝的自发曲率一般可以是弧长依赖的,我们研究了正弦变化的情况下,从任意的情况下,可以通过傅立叶变换重建。我们得到了力-伸展关系和横向涨落宽度的解析结果。我们发现,自发曲率波动可以影响力的延伸行为,即使在相对灵活的长丝的持续长度小于轮廓长度。

英文摘要:

Some important biomolecules (for instance, bacterial FtsZ and eukaryotic DNA) are known to posses spontaneous (intrinsic) curvature. Using a simple extension of the wormlike chain model, we study the response of a weakly bending filament in two dimensions to a pulling force applied at its ends (a configuration common in classical in-vitro experiments and relevant to several in-vivo cell cases). The spontaneous curvature of such a chain or filament can in general be arc-length dependent and we study a case of sinusoidal variation, from which an arbitrary case can be reconstructed via Fourier transformation. We obtain analytic results for the force-extension relationship and the width of transverse fluctuations. We show that spontaneous-curvature undulations can affect the force-extension behavior even in relatively flexible filaments with a persistence length smaller than the contour length.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑