基于生物化学逻辑系统的生物传感策略
Towards Biosensing Strategies Based on Biochemical Logic Systems
摘要：
生物化学计算的最新进展，利用实现计算门（例如AND、OR等）的主要酶促反应的级联的信息处理，以及在将这些门联网和将所得系统耦合到用于输出读出的智能/响应电极方面的进展，已经开启了新的生物传感机会。在这里，我们调查现有的研究成果，以及思想和研究途径，为未来发展的一个新的范例，数字化操作的生物传感器逻辑处理多个生化信号，通过布尔逻辑网络组成的生物分子反应，产生最终的输出信号是/否响应。与常见的单个或并联感测装置相比，这样的系统可以导致高保真度的生物感测。
英文摘要：
Recent advances in biochemical computing, i.e., information processing with cascades of primarily enzymatic reactions realizing computing gates, such as AND, OR, etc., as well as progress in networking these gates and coupling of the resulting systems to smart/responsive electrodes for output readout, have opened new biosensing opportunities. Here we survey existing enabling research results, as well as ideas and research avenues for future development of a new paradigm of digitally operating biosensors logically processing multiple biochemical signals through Boolean logic networks composed of biomolecular reactions, yielding the final output signals as YES/NO responses. Such systems can lead to high-fidelity biosensing compared to common single or parallel sensing devices.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
