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arXiv 0908.3135math.STstat.TH
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具有缺失数据的半参数加速失效时间模型的渐近理论

Asymptotic theory for the semiparametric accelerated failure time model with missing data

Bin Nan, John D. Kalbfleisch, Menggang Yu

摘要:

本文考虑一类具有缺失数据的转换(或加速失效时间)模型的双加权秩估计方法,例如在病例队列研究中。所考虑的权重可能无法按照鞅随机过程公式的要求进行预测。我们把一般问题作为一个半参数估计方程问题,并利用经验过程理论证明了加权估计的渐近性质,无论是真权估计还是估计权估计.仿真结果表明,结果依赖加权方法适用于有限样本的病例队列研究,并提高了效率相比,基于可预测的权重的方法。此外,可以看出,当使用估计权重时,该方法甚至更有效,这在缺失数据文献中是常见的情况。Gehan删失数据Wilcoxon权重被发现是令人惊讶的效率在广泛的一类问题。

英文摘要:

We consider a class of doubly weighted rank-based estimating methods for the transformation (or accelerated failure time) model with missing data as arise, for example, in case-cohort studies. The weights considered may not be predictable as required in a martingale stochastic process formulation. We treat the general problem as a semiparametric estimating equation problem and provide proofs of asymptotic properties for the weighted estimators, with either true weights or estimated weights, by using empirical process theory where martingale theory may fail. Simulations show that the outcome-dependent weighted method works well for finite samples in case-cohort studies and improves efficiency compared to methods based on predictable weights. Further, it is seen that the method is even more efficient when estimated weights are used, as is commonly the case in the missing data literature. The Gehan censored data Wilcoxon weights are found to be surprisingly efficient in a wide class of problems.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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