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arXiv 0811.0203q-bio.PEmath.AP
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从离散到连续演化模型:漂移扩散和复制子动力学的统一方法

From discrete to continuous evolution models: a unifying approach to drift-diffusion and replicator dynamics

Fabio A. C. C. Chalub, Max O. Souza

摘要:

我们研究了大人口极限的Moran过程,假设弱选择,并为不同的缩放。根据特定的缩放选择,我们得到一个连续的模型,可以突出遗传漂移(中性进化)或自然选择;对于一个精确的缩放,这两种效果都存在。对于考虑遗传漂移的缩放,连续模型由奇异扩散方程给出,连同已经存在于离散水平的两个守恒律。对于只考虑自然选择的标度,我们得到了一个双曲奇异方程,它嵌入了复制动力学,只满足一个守恒律。推导分为两个步骤:一个正式的,候选人的极限模型,并严格的概率密度的收敛性证明。还提出了关于固定概率的其他结果。

英文摘要:

We study the large population limit of the Moran process, assuming weak-selection, and for different scalings. Depending on the particular choice of scalings, we obtain a continuous model that may highlight the genetic-drift (neutral evolution) or natural selection; for one precise scaling, both effects are present. For the scalings that take the genetic-drift into account, the continuous model is given by a singular diffusion equation, together with two conservation laws that are already present at the discrete level. For scalings that take into account only natural selection, we obtain a hyperbolic singular equation that embeds the Replicator Dynamics and satisfies only one conservation law. The derivation is made in two steps: a formal one, where the candidate limit model is obtained, and a rigorous one, where convergence of the probability density is proved. Additional results on the fixation probabilities are also presented.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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