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arXiv 0810.1544q-bio.NC
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一大类爆发神经元多稳态性的机制、动力学和生物学存在

Mechanism, dynamics, and biological existence of multistability in a large class of bursting neurons

J. P. Newman, R. J. Butera

摘要:

多稳定性,在一个动力系统中的多个吸引子的共存,探讨了在爆裂神经细胞。一个建模研究表明,一大类的突发系统,定义为一个共享的拓扑结构时,表示为动态系统,本质上是适合于支持多稳态。我们推导出导致这些系统多稳定性的分岔结构和参数趋势。证据的存在多节奏的行为,在水生软体动物的加利福尼亚州,这是与我们提出的机制相一致的神经元。虽然这些实验结果是初步的,但它们表明,单个神经元可能能够动态地存储信息更长的时间尺度比通常归因于非突触机制。

英文摘要:

Multistability, the coexistence of multiple attractors in a dynamical system, is explored in bursting nerve cells. A modeling study is performed to show that a large class of bursting systems, as defined by a shared topology when represented as dynamical systems, is inherently suited to support multistability. We derive the bifurcation structure and parametric trends leading to multistability in these systems. Evidence for the existence of multirhythmic behavior in neurons of the aquatic mollusc Aplysia californica that is consistent with our proposed mechanism is presented. Although these experimental results are preliminary, they indicate that single neurons may be capable of dynamically storing information for longer time scales than typically attributed to nonsynaptic mechanisms.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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