遗传密码进化作为分子进化的初始驱动力
Genetic code evolution as an initial driving force for molecular evolution
摘要：
原始时期的分子进化与现代物种的基因组和蛋白质组的性质之间存在着内在的联系。基因组数据可以帮助我们从分子水平上理解生命进化的驱动力。过去，由于缺乏证据，分子进化中的许多问题不得不陷入猜测和争论的模糊地带。在这里，我们表明，基因组碱基组成和氨基酸频率的变化，从遗传密码进化的微妙结构。而生命进化的动力也起源于遗传密码进化。对氨基酸频率和基因组碱基组成变化的理论分析结果与实验观察结果吻合得很好，不仅在变化趋势上，而且在某些精细结构上也是如此。因此，现代物种的基因组数据可以帮助重建原始时期的遗传密码年代学和氨基酸年代学。我们的研究结果可能有助于揭示分子进化的内在机制和遗传密码的进化。
英文摘要：
There is an intrinsic relationship between the molecular evolution in primordial period and the properties of genomes and proteomes of contemporary species. The genomic data may help us understand the driving force of evolution of life at molecular level. In absence of evidence, numerous problems in molecular evolution had to fall into a twilight zone of speculation and controversy in the past. Here we show that delicate structures of variations of genomic base compositions and amino acid frequencies resulted from the genetic code evolution. And the driving force of evolution of life also originated in the genetic code evolution. The theoretical results on the variations of amino acid frequencies and genomic base compositions agree with the experimental observations very well, not only in the variation trends but also in some fine structures. Inversely, the genomic data of contemporary species can help reconstruct the genetic code chronology and amino acid chronology in primordial period. Our results may shed light on the intrinsic mechanism of molecular evolution and the genetic code evolution.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
