离子通道中的气泡门控电流
Bubble Gating Currents in Ionic Channels
摘要：
离子通道蛋白质中的气泡被认为是控制电流的闸门。与通道选通相关联的选通电流则将是气泡破裂和形成的电特征，其由气泡破裂或形成时介电系数的变化引起。气泡的介电系数为1。一个充满的气泡的介电系数（比如说）在30到80之间。预计转运蛋白、泵和通道将具有门控电流。
英文摘要：
Bubbles in ion channel proteins have been proposed to be the bistable gates that control current flow. Gating currents associated with channel gating would then be an electrical signature of bubble breaking and formation, arising from the change in dielectric coefficient as the bubble breaks or forms. A bubble would have a dielectric coefficient of 1. A filled bubble would have a dielectric coefficient (say) between 30 and 80. Transporters, pumps, and channels would be expected to have gating currents.
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