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arXiv 0709.0443q-bio.PEq-bio.CB
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类似的自组织尺度不变特性表征了早期癌症侵袭和远距离物种扩散

Similar self-organizing scale-invariant properties characterize early cancer invasion and long range species spread

D. E. Marco, S. A. Cannas, M. A. Montemurro, B. Hu, S. Cheng

摘要:

通过扩散占据新的栖息地是自然界的一个中心过程。特别是,远距离扩散与物种和流行病的传播有关,尽管它以前与癌症侵袭无关,这是一个涉及扩散到新组织的过程。我们发现,癌细胞的早期扩散是类似的物种个人传播,这两个过程是由一个共同的时空签名,其特征在于由一个特定的分形几何形状的边界生成的补丁,和幂律缩放,中断补丁大小分布。我们表明,这两个属性是一个直接的结果,远距离扩散,它们反映了同源生态过程的人口自组织。我们的研究结果对于涉及远距离扩散的过程(如生物入侵、流行病和癌症转移)具有重要意义。

英文摘要:

Occupancy of new habitats through dispersion is a central process in nature. In particular, long range dispersal is involved in the spread of species and epidemics, although it has not been previously related with cancer invasion, a process that involves spread to new tissues. We show that the early spread of cancer cells is similar to the species individuals spread and that both processes are represented by a common spatio-temporal signature, characterized by a particular fractal geometry of the boundaries of patches generated, and a power law-scaled, disrupted patch size distribution. We show that both properties are a direct result of long-distance dispersal, and that they reflect homologous ecological processes of population self-organization. Our results are significant for processes involving long-range dispersal like biological invasions, epidemics and cancer metastasis.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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