辉光放电Aes在生物医学中金属离子和水研究中的应用
Application of Glow Discharge Aes for Investigation of Metal Ions and Water in Biology and Medicine
摘要:
AES甚高频电感耦合等离子体管可用于广泛的研究。它可以快速微量分析各种溶液,包括生物对象和外周血血清。此外,它还可用于固体中水分解吸的研究和含能金属-高分子络合物的测定。通过水辉光放电动力学曲线对Na-DNA增湿纤维的氢解吸进行原子光谱分析(GD EAS氢分析),研究了水化能和水化数,揭示了水化水分子的结构和构象变化的活化能增加0.65千卡/摩尔水。所开发的分析含有高浓度有机材料的溶液中的元素的方法允许对实际健康的人进行系统研究,并揭示了几种疾病的风险因素。血清微量元素含量表明,血清中未结合铜蓝蛋白铜的含量在肢肉芽肿病组比健康人高3倍。
英文摘要:
AES VHF inductively coupled plasmatron may be applied to wide range of studies. It enables rapid microanalysis of various solutions including biological objects and peripheral blood serum. In addition, it may be used for investigation of water desorption from solid bodies and for determination of energetic metal-macromolecule complexes. Study of hydration energy and hydration number by kinetic curves of water glow discharge atomic spectral analysis of hydrogen (GD EAS analysis of hydrogen) desorption from Na-DNA humidified fibers allowed to reveal that structural and conformational changes in activation energy of hydrated water molecules increases by 0.65kcal/Mole of water. The developed method of analysis of elements in solutions containing high concentrations of organic materials allows systematic study of practically healthy persons and reveals risk factors for several diseases. Microelemental content of blood serum fractions showed that amount of not bounded with ceruloplasmin copper was three times more at limphogranulomatose disease than that in healthy persons.
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