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arXiv 0707.2890q-bio.PE
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利用三联体构建二级系统发育网络

Constructing level-2 phylogenetic networks from triplets

Leo van Iersel, Judith Keijsper, Steven Kelk, Leen Stougie

摘要:

Jansson和Sung证明,给定一组密集的输入三元组T(代表物种三元组局部进化关系的假设),可以在多项式时间内确定是否存在与T一致的一级网络,如果存在,则可以构建这样的网络。他们还表明,与树(即0级网络)的情况不同,当输入是非稠密的时,问题变得NP难。在这里,我们进一步扩展这项工作表明,当一组输入三元组是密集的,这个问题甚至是多项式时间可解的2级网络的建设。这表明,假设密度,它是易于处理的,以构建合理的进化历史,从输入三元组,即使这样的历史是严重的非树一样。这进一步加强了在构建系统发育网络中使用基于三联体的方法的情况。我们还表明,在非密集的情况下,2级问题仍然是NP难的。

英文摘要:

Jansson and Sung showed that, given a dense set of input triplets T (representing hypotheses about the local evolutionary relationships of triplets of species), it is possible to determine in polynomial time whether there exists a level-1 network consistent with T, and if so to construct such a network. They also showed that, unlike in the case of trees (i.e. level-0 networks), the problem becomes NP-hard when the input is non-dense. Here we further extend this work by showing that, when the set of input triplets is dense, the problem is even polynomial-time solvable for the construction of level-2 networks. This shows that, assuming density, it is tractable to construct plausible evolutionary histories from input triplets even when such histories are heavily non-tree like. This further strengthens the case for the use of triplet-based methods in the construction of phylogenetic networks. We also show that, in the non-dense case, the level-2 problem remains NP-hard.

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