Effective Biological Representation Learning by Masking Gene Expression
通过掩码基因表达实现有效的生物表示学习
机构 * Recursion ; Valence Labs ; École Normale Supérieure PSL
AI总结 提出自监督模型TxFM,采用掩码自编码方法处理RNA-seq数据,通过消融研究确定关键架构,并在精心策划的DiverseRNA-1.4M数据集上训练,获得优于大规模基础模型的基因表示。
Comments 31 pages, 11 figures. Preprint; presented at ICLR 2026 2nd Workshop on Foundation Models for Science: Real-World Impact and Science-First Design