医学 AI

Engineering Spatial and Molecular Features from Cellular Niches to Inform Predictions of Inflammatory Bowel Disease

从细胞微环境工程化空间和分子特征以指导炎症性肠病的预测

Myles Joshua Toledo Tan, Maria Kapetanaki, Panayiotis V. Benos

机构 * Department of Electrical and Computer Engineering, Herbert Wertheim College of Engineering, University of Florida（电气与计算机工程系，赫伯特·韦斯剧院工程学院，佛罗里达大学） ； Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida（流行病学系，公共卫生与健康专业学院及医学院，佛罗里达大学） ； Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida（药理学与转化研究系，药学院，佛罗里达大学） 纠错

专题命中 诊断辅助 ：pathology(abstract)；分类 cs.LG、q-bio

AI总结 本研究通过空间转录组学构建可解释的机器学习模型，利用细胞微环境特征区分IBD亚型，提升炎症性肠病的诊断准确性与生物机制理解。

Comments 20 pages, 8 figures, 7 tables. Presented at the 37th Benelux Conference on Artificial Intelligence / 34th Belgian Dutch Conference on Machine Learning, Namur, Belgium, November 19 - 21, 2025

Papanicolaou Stain Unmixing for RGB Image Using Weighted Nucleus Sparsity and Total Variation Regularization

使用加权核稀疏性和全变分正则化的RGB图像Papanicolaou染色分离

Nanxin Gong, Saori Takeyama, Masahiro Yamaguchi, Takumi Urata, Fumikazu Kimura, Keiko Ishii

专题命中 诊断辅助 ：diagnosis(abstract)；分类 q-bio、eess.IV

AI总结 本文提出了一种无需训练的RGB图像Papanicolaou染色分离方法，利用加权核稀疏性和全变分正则化，实现了高精度的染色量化和细胞分类。

Comments Accepted and published in Medical & Biological Engineering & Computing (2025). https://doi.org/10.1007/s11517-025-03490-z

Journal ref Med Biol Eng Comput (2025)

Anatomical basis of sex differences in the electrocardiogram identified by three-dimensional torso-heart imaging reconstruction pipeline

心电图中性别的差异的解剖基础通过三维躯体-心脏成像重建流程确定

Hannah J. Smith, Blanca Rodriguez, Yuling Sang, Marcel Beetz, Robin P. Choudhury, Vicente Grau, Abhirup Banerjee

专题命中 诊断辅助 ：diagnosis(abstract)；分类 q-bio、eess.IV

AI总结 本研究通过三维躯体-心脏成像重建流程，揭示了性别差异在心电图特征和解剖结构中的关系，强调了量化性别差异对心电图解读和临床应用的重要性。

Comments Revision following reviewer comments

MAT-MPNN: A Mobility-Aware Transformer-MPNN Model for Dynamic Spatiotemporal Prediction of HIV Diagnoses in California, Florida, and New England

Zhaoxuan Wang, Weichen Kang, Yutian Han, Lingyuan Zhao, Bo Li

机构 * Department of Statistics, Washington University in St.Louis（统计系，华盛顿大学圣路易斯分校） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 21 pages, 20 figures,1 table. Preprint

De-Individualizing fMRI Signals via Mahalanobis Whitening and Bures Geometry

Aaron Jacobson, Tingting Dan, Martin Styner, Guorong Wu, Shahar Kovalsky, Caroline Moosmueller

机构 * Department of Mathematics, University of North Carolina at Chapel Hill（数学系，北卡罗来纳大学教堂山分校） ； Department of Psychiatry, University of North Carolina at Chapel Hill（精神病学系，北卡罗来纳大学教堂山分校） ； Department of Biomedical Engineering, University of Basel（生物医学工程系，巴塞尔大学） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 34 pages, 7 figures

Gut decisions based on the liver: A radiomics approach to boost colorectal cancer screening

Anna Hinterberger, Jonas Bohn, Dasha Trofimova, Nicolas Knabe, Julia Dettling, Tobias Norajitra, Fabian Isensee, Johannes Betge, Stefan O. Schönberg, Dominik Nörenberg, Sergio Grosu, Sonja Loges, Ralf Floca, Jakob Nikolas Kather, Klaus Maier-Hein, Freba Grawe

专题命中 诊断辅助 ：CT(abstract)；分类 q-bio、eess.IV

Comments Equal contribution between first, second, fifteenth, and sixteenth authors

Engram Memory Encoding and Retrieval: A Neurocomputational Perspective

Daniel Szelogowski

机构 * Department of Computer Science University of Wisconsin-Whitewater（计算机科学系 威斯康星大学-惠特ewater分校） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 18 pages, 7 figures, 3 tables

Foundation Models in Dermatopathology: Skin Tissue Classification

Riya Gupta, Yiwei Zong, Dennis H. Murphree

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.CV、q-bio

Multi-Scale Graph Theoretical Analysis of Resting-State fMRI for Classification of Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Controls

Ali Khazaee, Abdolreza Mohammadi, Ruairi O'Reilly

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Journal ref SIViP 19, 1192 (2025)

DCA: Graph-Guided Deep Embedding Clustering for Brain Atlases

Mo Wang, Kaining Peng, Jingsheng Tang, Hongkai Wen, Quanying Liu

机构 * SUSTech（南方科技大学） ； University of Warwick（沃里克大学） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.CV、q-bio

Comments Accepted as a poster at NeurIPS 2025 with scores 5554

Mentality: A Mamba-based Approach towards Foundation Models for EEG

Saarang Panchavati, Corey Arnold, William Speier

机构 * Department of Radiology University of California（放射科系 加州大学） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Journal ref In Proceedings of the ICLR 2024 Workshop on Learning from Time Series for Health (2024). Retrieved from https://openreview.net/forum?id=O6T38rRiFp

Cost-Effective Active Labeling for Data-Efficient Cervical Cell Classification

Yuanlin Liu, Zhihan Zhou, Mingqiang Wei, Youyi Song

机构 * School of Science（科学学院） ； China Pharmaceutical University（中国药科大学） ； College of Computer Science and Technology（计算机科学与技术学院） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.CV、q-bio

Comments accepted by CW2025

An Uncertainty-Aware Dynamic Decision Framework for Progressive Multi-Omics Integration in Classification Tasks

Nan Mu, Hongbo Yang, Chen Zhao

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Automatic Depression Assessment using Machine Learning: A Comprehensive Survey

Siyang Song, Yupeng Huo, Shiqing Tang, Jiaee Cheong, Rui Gao, Michel Valstar, Hatice Gunes

机构 * HBUG Lab, Department of Computer Science, University of Exeter（埃克塞特大学计算机科学系） ； Department of Computer Science and Technology, University of Cambridge（剑桥大学计算机科学与技术系） ； University of California, Los Angeles（加州大学洛杉矶分校） ； Computer Vision Lab, School of Computer Science, University of Nottingham（诺丁汉大学计算机科学学院） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

A Robust Support Vector Machine Approach for Raman COVID-19 Data Classification

Marco Piazza, Andrea Spinelli, Francesca Maggioni, Marzia Bedoni, Enza Messina

机构 * Department of Informatics, Systems and Communication, University of Milano-Bicocca（信息学、系统与通信系，米兰-比科卡大学） ； Department of Management, Information and Production Engineering, University of Bergamo（管理、信息与生产工程系，博尔盖塞大学） 纠错

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Cross-Modal Epileptic Signal Harmonization: Frequency Domain Mapping Quantization for Pre-training a Unified Neurophysiological Transformer

Runkai Zhang, Hua Yu, John Q. Gan, Haixian Wang

专题命中 诊断辅助 ：diagnosis(abstract)；分类 q-bio、eess.SP

Advancing Digital Precision Medicine for Chronic Fatigue Syndrome through Longitudinal Large-Scale Multi-Modal Biological Omics Modeling with Machine Learning and Artificial Intelligence

Ruoyun Xiong

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

When will the mist clear? On the Interpretability of Machine Learning for Medical Applications: a survey

Antonio-Jesús Banegas-Luna, Jorge Peña-García, Adrian Iftene, Fiorella Guadagni, Patrizia Ferroni, Noemi Scarpato, Fabio Massimo Zanzotto, Andrés Bueno-Crespo, Horacio Pérez-Sánchez

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 64 pages, 3 figures, 7 tables, +100 references

Journal ref Int. J. Mol. Sci. 2021, 22(9), 4394

Can a Quantum Support Vector Machine algorithm be utilized to identify Key Biomarkers from Multi-Omics data of COVID19 patients?

Junggu Choi, Chansu Yu, Kyle L. Jung, Suan-Sin Foo, Weiqiang Chen, Suzy AA Comhair, Serpil C. Erzurum, Lara Jehi, Jae U. Jung

专题命中 诊断辅助 ：biomedical(abstract)；分类 cs.LG、q-bio

Comments 70 pages, 6 figures

Early Detection of Cognitive Impairment in Elderly using a Passive FPVS-EEG BCI and Machine Learning -- Extended Version

Tomasz M. Rutkowski, Stanisław Narębski, Mihoko Otake-Matsuura, Tomasz Komendziński

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 4 pages, 4 figures, exteded version of an abstract accepted for a poster presentation at the 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC2025), Copenhagen, Denmark, July 14-17, 2025

Artificial Intelligence and Diabetes Mellitus: An Inside Look Through the Retina

Yasin Sadeghi Bazargani, Majid Mirzaei, Navid Sobhi, Mirsaeed Abdollahi, Ali Jafarizadeh, Siamak Pedrammehr, Roohallah Alizadehsani, Ru San Tan, Sheikh Mohammed Shariful Islam, U. Rajendra Acharya

专题命中 诊断辅助 ：diagnosis(abstract)；分类 q-bio、eess.IV

Comments 44 Pages, 6 figures, 1 table, 166 references

BrainNet-MoE: Brain-Inspired Mixture-of-Experts Learning for Neurological Disease Identification

Jing Zhang, Xiaowei Yu, Tong Chen, Chao Cao, Mingheng Chen, Yan Zhuang, Yanjun Lyu, Lu Zhang, Li Su, Tianming Liu, Dajiang Zhu

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

A Foundational Brain Dynamics Model via Stochastic Optimal Control

Joonhyeong Park, Byoungwoo Park, Chang-Bae Bang, Jungwon Choi, Hyungjin Chung, Byung-Hoon Kim, Juho Lee

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments The first two authors contributed equally

BrainOOD: Out-of-distribution Generalizable Brain Network Analysis

Jiaxing Xu, Yongqiang Chen, Xia Dong, Mengcheng Lan, Tiancheng Huang, Qingtian Bian, James Cheng, Yiping Ke

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Handwriting Anomalies and Learning Disabilities through Recurrent Neural Networks and Geometric Pattern Analysis

Vasileios Alevizos, Sabrina Edralin, Akebu Simasiku, Dimitra Malliarou, Antonis Messinis, George Papakostas, Clark Xu, Zongliang Yue

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Pan-infection Foundation Framework Enables Multiple Pathogen Prediction

Lingrui Zhang, Haonan Wu, Nana Jin, Chenqing Zheng, Jize Xie, Qitai Cai, Jun Wang, Qin Cao, Xubin Zheng, Jiankun Wang, Lixin Cheng

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 15 pages, 8 figures

Not All Errors Are Equal: Investigation of Speech Recognition Errors in Alzheimer's Disease Detection

Jiawen Kang, Junan Li, Jinchao Li, Xixin Wu, Helen Meng

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments Accepted by IEEE ISCSLP 2024

eDOC: Explainable Decoding Out-of-domain Cell Types with Evidential Learning

Chaochen Wu, Meiyun Zuo, Lei Xie

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments under review

Disentangling Interpretable Factors with Supervised Independent Subspace Principal Component Analysis

Jiayu Su, David A. Knowles, Raul Rabadan

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio

Comments 10 pages and 6 figures in the main text; To be published in the Proceedings of the 38th Conference on Neural Information Processing Systems (NeurIPS 2024)

HyperBrain: Anomaly Detection for Temporal Hypergraph Brain Networks

Sadaf Sadeghian, Xiaoxiao Li, Margo Seltzer

专题命中 诊断辅助 ：diagnosis(abstract)；分类 cs.LG、q-bio